Drug Disease Association (DDA)


The DDA model analyzes the associations between drugs and diseases, assessing the potential of existing drugs in treating specific diseases.

By mining the relationships between drugs and diseases, researchers can discover underutilized drugs, advancing the process of drug repositioning.


The search result for the Model Prediction Types "Drug Disease Association (DDA)"
A total of 399 results found based on your keywords
Recommendation ID Data Information Model Information Application Information Reference
Rank Total_Score Model_ID Dataset_Name Element_type Data_features Model_name Algorithm_name Prediction_type Code_source Study_types Disease_name Target_name Drug_name Interaction_type Recommended_Number PMID Journal Publication_Year
1 90.6 1539 Ldataset Drug, Disease Drug: SMILES, Disease: MeSH DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/TheWall9/DRHGCN Case studies Alzheimer's disease (AD) NA NA NA Top 10 drugs 34378011 Brief Bioinform 2021
1 90.6 1539 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/TheWall9/DRHGCN Case studies Alzheimer's disease (AD) NA NA NA Top 10 drugs 34378011 Brief Bioinform 2021
1 90.6 1539 Ldataset Drug, Disease Drug: SMILES, Disease: MeSH DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/TheWall9/DRHGCN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 34378011 Brief Bioinform 2021
1 90.6 1539 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/TheWall9/DRHGCN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 34378011 Brief Bioinform 2021
1 90.6 1539 LRSSL Drug, Disease Drug: SMILES, Disease: MeSH DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/TheWall9/DRHGCN Case studies Alzheimer's disease (AD) NA NA NA Top 10 drugs 34378011 Brief Bioinform 2021
1 90.6 1539 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/TheWall9/DRHGCN Case studies Alzheimer's disease (AD) NA NA NA Top 10 drugs 34378011 Brief Bioinform 2021
1 90.6 1539 LRSSL Drug, Disease Drug: SMILES, Disease: MeSH DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/TheWall9/DRHGCN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 34378011 Brief Bioinform 2021
1 90.6 1539 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/TheWall9/DRHGCN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 34378011 Brief Bioinform 2021
2 87.8 2207 Dataset 3 Drug, Disease Drug: SMILES, Disease: Mesh semantic DRDSA (Drug Repositioning Deep Sparse Autoencoder) Deep sparse autoencoder,Deep feedforward neural network Drug Disease Association (DDA) https://github.com/luckymengmeng/HDVD Case studies COVID-19 NA NA NA Top 10 drugs 38103130 Interdiscip Sci 2024
2 87.8 2207 Dataset 4 Drug, Disease Drug: SMILES, Disease: Mesh semantic DRDSA (Drug Repositioning Deep Sparse Autoencoder) Deep sparse autoencoder,Deep feedforward neural network Drug Disease Association (DDA) https://github.com/luckymengmeng/HDVD Case studies COVID-19 NA NA NA Top 10 drugs 38103130 Interdiscip Sci 2024
2 87.8 2207 Dataset 1 Drug, Disease Drug: SMILES, Disease: Mesh semantic DRDSA (Drug Repositioning Deep Sparse Autoencoder) Deep sparse autoencoder,Deep feedforward neural network Drug Disease Association (DDA) https://github.com/luckymengmeng/HDVD Case studies COVID-19 NA NA NA Top 10 drugs 38103130 Interdiscip Sci 2024
2 87.8 2207 Dataset 2 Drug, Disease Drug: SMILES, Disease: Mesh semantic DRDSA (Drug Repositioning Deep Sparse Autoencoder) Deep sparse autoencoder,Deep feedforward neural network Drug Disease Association (DDA) https://github.com/luckymengmeng/HDVD Case studies COVID-19 NA NA NA Top 10 drugs 38103130 Interdiscip Sci 2024
3 86.5 1868 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH GLGMPNN Message Passing Neural Network (MPNN), Gated Fusion Mechanism Drug Disease Association (DDA) https://github.com/bdtree/GLGMPNN Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 36305457 Brief Bioinform 2022
3 86.5 1868 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH GLGMPNN Message Passing Neural Network (MPNN), Gated Fusion Mechanism Drug Disease Association (DDA) https://github.com/bdtree/GLGMPNN Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 36305457 Brief Bioinform 2022
4 86.05 2168 Bdataset Drug, Disease, Target Drug: SMILES, Disease: MesH, Target: Sequence HMLKGAT Graph Attention Network (The principle of three degrees influence),Multi-Kernel Learning Method (Gaussian kernel function,Cosine similarity function),Neural network Drug Disease Association (DDA) https://github.com/LDD-0914/HMLKGAT.git Case studies NA NA NA Drug disease interaction Top 5 diseases 38051617 IEEE/ACM Trans Comput Biol Bioinform 2024
4 86.05 2168 Hetero-A Drug, Disease, Target NA HMLKGAT Graph Attention Network (The principle of three degrees influence),Multi-Kernel Learning Method (Gaussian kernel function,Cosine similarity function),Neural network Drug Disease Association (DDA) https://github.com/LDD-0914/HMLKGAT.git Case studies NA NA NA Drug disease interaction Top 5 diseases 38051617 IEEE/ACM Trans Comput Biol Bioinform 2024
5 85.4 815 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Levodopa NA Top 5 diseases 31869322 PLoS Comput Biol 2019
5 85.4 815 Cdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Flecainide NA Top 5 diseases 31869322 PLoS Comput Biol 2019
5 85.4 815 PREDICT (Fdataset) Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Flecainide NA Top 5 diseases 31869322 PLoS Comput Biol 2019
5 85.4 815 Cdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Levodopa NA Top 5 diseases 31869322 PLoS Comput Biol 2019
5 85.4 815 PREDICT (Fdataset) Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Levodopa NA Top 5 diseases 31869322 PLoS Comput Biol 2019
5 85.4 815 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Doxorubicin NA Top 5 diseases 31869322 PLoS Comput Biol 2019
5 85.4 815 Cdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Doxorubicin NA Top 5 diseases 31869322 PLoS Comput Biol 2019
5 85.4 815 PREDICT (Fdataset) Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Doxorubicin NA Top 5 diseases 31869322 PLoS Comput Biol 2019
5 85.4 815 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Flecainide NA Top 5 diseases 31869322 PLoS Comput Biol 2019
6 85 1566 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Dexamethasone NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Amantadine NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Gabapentin NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Doxorubicin NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Flecainide NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Frovatriptan NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Dexamethasone NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Amantadine NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Gabapentin NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Doxorubicin NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Flecainide NA Top 20 diseases 34610633 Mol Omics 2021
6 85 1566 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH BGMSDDA K nearest known neighbors (WKNKN) Drug Disease Association (DDA) https://github.com/kk-2010000/BGMSDDA Case studies NA NA Frovatriptan NA Top 20 diseases 34610633 Mol Omics 2021
7 84.3 1807 NA Drug, Disease Drug: SMILES, Disease: Mesh semantic GCMM (Graph convolution network based on a multimodal attention mechanism) Convolutional Neural Network (CNN) Drug Disease Association (DDA) https://github.com/FanZhang0820/GCMM Case studies Alzheimer's Disease (AD) NA NA NA Top 5 drugs 36100897 BMC Bioinformatics 2022
8 84.04 289 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Amantadine NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Cabergoline NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Levodopa NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Doxorubicin NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Cabergoline NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Levodopa NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Flecainide NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Amantadine NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Cabergoline NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Levodopa NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Flecainide NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Doxorubicin NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Amantadine NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Flecainide NA Top 5 diseases 27153662 Bioinformatics 2016
8 84.04 289 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms MBiRW Random Walk Drug Disease Association (DDA) http://github.com//bioinfomaticsCSU/MBiRW Case studies NA NA Doxorubicin NA Top 5 diseases 27153662 Bioinformatics 2016
9 83.8 893 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH HNet-DNN Deep Neural Network (DNN) Drug Disease Association (DDA) https://github.com/hliu2016/HNet-DNN Case studies Breast neoplasms NA NA NA Top 15 drugs 32118415 J Chem Inf Model 2020
9 83.8 893 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH HNet-DNN Deep Neural Network (DNN) Drug Disease Association (DDA) https://github.com/hliu2016/HNet-DNN Case studies NA NA Enalapril NA Top 15 diseases 32118415 J Chem Inf Model 2020
9 83.8 893 PREDICT (Fdataset) Drug, Disease Drug: SMILES, Disease: MeSH HNet-DNN Deep Neural Network (DNN) Drug Disease Association (DDA) https://github.com/hliu2016/HNet-DNN Case studies Breast neoplasms NA NA NA Top 15 drugs 32118415 J Chem Inf Model 2020
9 83.8 893 PREDICT (Fdataset) Drug, Disease Drug: SMILES, Disease: MeSH HNet-DNN Deep Neural Network (DNN) Drug Disease Association (DDA) https://github.com/hliu2016/HNet-DNN Case studies NA NA Enalapril NA Top 15 diseases 32118415 J Chem Inf Model 2020
10 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Metoprolol NA Top 10 diseases 34850815 Brief Bioinform 2022
10 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Propranolol NA Top 10 diseases 34850815 Brief Bioinform 2022
10 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Aripiprazole NA Top 10 diseases 34850815 Brief Bioinform 2022
10 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Chloroquine NA Top 10 diseases 34850815 Brief Bioinform 2022
10 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Flurbiprofen NA Top 10 diseases 34850815 Brief Bioinform 2022
11 82.7 1848 Bdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies Breast neoplasms NA NA NA Top 10 drugs 36182762 Comput Biol Med 2022
11 82.7 1848 NA Drug, Disease, Target, Gene, Pathway Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies Breast neoplasms NA NA NA Top 10 drugs 36182762 Comput Biol Med 2022
11 82.7 1848 NA Drug, Disease, Target, Gene, Pathway Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies Brain neoplasms NA NA NA Top 10 drugs 36182762 Comput Biol Med 2022
11 82.7 1848 Bdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies Brain neoplasms NA NA NA Top 10 drugs 36182762 Comput Biol Med 2022
11 82.7 1848 Bdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies NA NA Dexamethasone NA Top 10 diseases 36182762 Comput Biol Med 2022
11 82.7 1848 NA Drug, Disease, Target, Gene, Pathway Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies NA NA Dexamethasone NA Top 10 diseases 36182762 Comput Biol Med 2022
11 82.7 1848 Bdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies NA NA Ifosfamide NA Top 10 diseases 36182762 Comput Biol Med 2022
11 82.7 1848 NA Drug, Disease, Target, Gene, Pathway Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies NA NA Ifosfamide NA Top 10 diseases 36182762 Comput Biol Med 2022
12 82.1 1842 LRSSL Drug, Disease Drug: SMILES, Disease: MeSH PSGCN (Partner-specific drug repositioning approach based on graph convolutional network） Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/xinliangSun/PSGCN Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 10 drugs 35921345 IEEE J Biomed Health Inform 2022
12 82.1 1842 Gdataset Drug, Disease Drug: SMILES, Disease: MeSH PSGCN (Partner-specific drug repositioning approach based on graph convolutional network） Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/xinliangSun/PSGCN Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 10 drugs 35921345 IEEE J Biomed Health Inform 2022
12 82.1 1842 LRSSL Drug, Disease Drug: SMILES, Disease: MeSH PSGCN (Partner-specific drug repositioning approach based on graph convolutional network） Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/xinliangSun/PSGCN Case studies Breast Cancer NA NA NA Top 10 drugs 35921345 IEEE J Biomed Health Inform 2022
12 82.1 1842 Gdataset Drug, Disease Drug: SMILES, Disease: MeSH PSGCN (Partner-specific drug repositioning approach based on graph convolutional network） Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/xinliangSun/PSGCN Case studies Breast Cancer NA NA NA Top 10 drugs 35921345 IEEE J Biomed Health Inform 2022
12 82.1 1842 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH PSGCN (Partner-specific drug repositioning approach based on graph convolutional network） Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/xinliangSun/PSGCN Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 10 drugs 35921345 IEEE J Biomed Health Inform 2022
12 82.1 1842 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH PSGCN (Partner-specific drug repositioning approach based on graph convolutional network） Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/xinliangSun/PSGCN Case studies Breast Cancer NA NA NA Top 10 drugs 35921345 IEEE J Biomed Health Inform 2022
13 81.9 2175 Gdataset (Fdataset) Drug, Disease Drug: 2D chemical fingerprints, Diseases: The semantic similarity of disease phenotypes AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Adaptive Graph Convolutional Network (AGCN) Drug Disease Association (DDA) https://github.com/xinliangSun/AdaDR Case studies Alzheimer's Disease (AD) NA NA NA Top 5 drugs 38070161 Bioinformatics 2024
13 81.9 1643 Cdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Indomethacin NA Top 10 diseases 34864881 Bioinformatics 2022
13 81.9 1643 Fdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Diltiazem NA Top 10 diseases 34864881 Bioinformatics 2022
13 81.9 2175 LRSSL Drug, Disease Drug: 2D chemical fingerprints, Diseases: The semantic similarity of disease phenotypes AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Adaptive Graph Convolutional Network (AGCN) Drug Disease Association (DDA) https://github.com/xinliangSun/AdaDR Case studies Alzheimer's Disease (AD) NA NA NA Top 5 drugs 38070161 Bioinformatics 2024
13 81.9 2175 LRSSL Drug, Disease Drug: 2D chemical fingerprints, Diseases: The semantic similarity of disease phenotypes AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Adaptive Graph Convolutional Network (AGCN) Drug Disease Association (DDA) https://github.com/xinliangSun/AdaDR Case studies Breast carcinoma NA NA NA Top 5 drugs 38070161 Bioinformatics 2024
13 81.9 2175 Gdataset (Fdataset) Drug, Disease Drug: 2D chemical fingerprints, Diseases: The semantic similarity of disease phenotypes AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Adaptive Graph Convolutional Network (AGCN) Drug Disease Association (DDA) https://github.com/xinliangSun/AdaDR Case studies Breast carcinoma NA NA NA Top 5 drugs 38070161 Bioinformatics 2024
13 81.9 1643 DNdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Fenoldopam NA Top 10 diseases 34864881 Bioinformatics 2022
13 81.9 1643 Fdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Indomethacin NA Top 10 diseases 34864881 Bioinformatics 2022
13 81.9 2175 Ldataset Drug, Disease Drug: 2D chemical fingerprints, Diseases: The semantic similarity of disease phenotypes AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Adaptive Graph Convolutional Network (AGCN) Drug Disease Association (DDA) https://github.com/xinliangSun/AdaDR Case studies Alzheimer's Disease (AD) NA NA NA Top 5 drugs 38070161 Bioinformatics 2024
13 81.9 2175 Cdataset Drug, Disease Drug: 2D chemical fingerprints, Diseases: The semantic similarity of disease phenotypes AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Adaptive Graph Convolutional Network (AGCN) Drug Disease Association (DDA) https://github.com/xinliangSun/AdaDR Case studies Alzheimer's Disease (AD) NA NA NA Top 5 drugs 38070161 Bioinformatics 2024
13 81.9 1643 DNdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Diltiazem NA Top 10 diseases 34864881 Bioinformatics 2022
13 81.9 1643 Cdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Fenoldopam NA Top 10 diseases 34864881 Bioinformatics 2022
13 81.9 1643 Fdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Fenoldopam NA Top 10 diseases 34864881 Bioinformatics 2022
13 81.9 2175 Ldataset Drug, Disease Drug: 2D chemical fingerprints, Diseases: The semantic similarity of disease phenotypes AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Adaptive Graph Convolutional Network (AGCN) Drug Disease Association (DDA) https://github.com/xinliangSun/AdaDR Case studies Breast carcinoma NA NA NA Top 5 drugs 38070161 Bioinformatics 2024
13 81.9 2175 Cdataset Drug, Disease Drug: 2D chemical fingerprints, Diseases: The semantic similarity of disease phenotypes AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Adaptive Graph Convolutional Network (AGCN) Drug Disease Association (DDA) https://github.com/xinliangSun/AdaDR Case studies Breast carcinoma NA NA NA Top 5 drugs 38070161 Bioinformatics 2024
13 81.9 1643 DNdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Indomethacin NA Top 10 diseases 34864881 Bioinformatics 2022
13 81.9 1643 Cdataset Drug, Disease Drug: Hashed fingerprints, Disease: MeSH springD²A Encoder,Neural networks Drug Disease Association (DDA) https://github.com/wangyuanhao/springD2A Case studies NA NA Diltiazem NA Top 10 diseases 34864881 Bioinformatics 2022
14 81.88 1407 Fdataset Drug, Disease Drug: SMILES, ATC, side-effect; Disease: the medical subject headings vocabulary, DO. MSBMF Matrix Factorization Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MSBMF Case studies NA NA Vincristine NA Top 10 diseases 33147616 Brief Bioinform 2021
14 81.88 1407 Fdataset Drug, Disease Drug: SMILES, ATC, side-effect; Disease: the medical subject headings vocabulary, DO. MSBMF Matrix Factorization Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MSBMF Case studies NA NA Methotrexate NA Top 10 diseases 33147616 Brief Bioinform 2021
14 81.88 1407 Fdataset Drug, Disease Drug: SMILES, ATC, side-effect; Disease: the medical subject headings vocabulary, DO. MSBMF Matrix Factorization Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MSBMF Case studies NA NA Risperidone NA Top 10 diseases 33147616 Brief Bioinform 2021
14 81.88 1407 Fdataset Drug, Disease Drug: SMILES, ATC, side-effect; Disease: the medical subject headings vocabulary, DO. MSBMF Matrix Factorization Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MSBMF Case studies NA NA Doxorubicin NA Top 10 diseases 33147616 Brief Bioinform 2021
14 81.88 1407 Fdataset Drug, Disease Drug: SMILES, ATC, side-effect; Disease: the medical subject headings vocabulary, DO. MSBMF Matrix Factorization Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MSBMF Case studies NA NA Gemcitabine NA Top 10 diseases 33147616 Brief Bioinform 2021
15 81.8 795 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms SKCNN Sigmoid Kernel and Convolutional Neural Network (SKCNN),Support Vector Machine (SVM) Drug Disease Association (DDA) https://github.com/HanJingJiang/SKCNN Case studies Asthma NA NA NA Top 20 drugs 31747915 J Transl Med 2019
15 81.8 795 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms SKCNN Sigmoid Kernel and Convolutional Neural Network (SKCNN),Support Vector Machine (SVM) Drug Disease Association (DDA) https://github.com/HanJingJiang/SKCNN Case studies Obesity NA NA NA Top 20 drugs 31747915 J Transl Med 2019
15 81.8 795 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms SKCNN Sigmoid Kernel and Convolutional Neural Network (SKCNN),Support Vector Machine (SVM) Drug Disease Association (DDA) https://github.com/HanJingJiang/SKCNN Case studies Asthma NA NA NA Top 20 drugs 31747915 J Transl Med 2019
15 81.8 795 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms SKCNN Sigmoid Kernel and Convolutional Neural Network (SKCNN),Support Vector Machine (SVM) Drug Disease Association (DDA) https://github.com/HanJingJiang/SKCNN Case studies Obesity NA NA NA Top 20 drugs 31747915 J Transl Med 2019
16 81.4 1860 T2 Drug, Disease, Target Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies NA NA Felodipine NA Top 5 diseases 36359016 Biomolecules 2022
16 81.4 1718 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH MLMC Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MLMC Case studies NA NA Leucovorin NA Top 5 diseases 35289352 Brief Bioinform 2022
16 81.4 1860 T1 Drug, Disease, Target Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 36359016 Biomolecules 2022
16 81.4 1860 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies Breast carcinoma NA NA NA Top 10 drugs 36359016 Biomolecules 2022
16 81.4 1860 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 36359016 Biomolecules 2022
16 81.4 1860 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies Breast carcinoma NA NA NA Top 10 drugs 36359016 Biomolecules 2022
16 81.4 1718 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH MLMC Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MLMC Case studies NA NA Doxorubicin NA Top 5 diseases 35289352 Brief Bioinform 2022
16 81.4 1860 T1 Drug, Disease, Target Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies NA NA Felodipine NA Top 5 diseases 36359016 Biomolecules 2022
16 81.4 1860 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies NA NA Felodipine NA Top 5 diseases 36359016 Biomolecules 2022
16 81.4 1860 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 36359016 Biomolecules 2022
16 81.4 1860 T2 Drug, Disease, Target Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies Breast carcinoma NA NA NA Top 10 drugs 36359016 Biomolecules 2022
16 81.4 1718 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH MLMC Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MLMC Case studies NA NA Gemcitabine NA Top 5 diseases 35289352 Brief Bioinform 2022
16 81.4 1718 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH MLMC Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/MLMC Case studies NA NA Methotrexate NA Top 5 diseases 35289352 Brief Bioinform 2022
16 81.4 1860 T1 Drug, Disease, Target Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies Breast carcinoma NA NA NA Top 10 drugs 36359016 Biomolecules 2022
16 81.4 1860 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies NA NA Felodipine NA Top 5 diseases 36359016 Biomolecules 2022
16 81.4 1860 T2 Drug, Disease, Target Drug: SMILES, Disease: MeSH EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/hwh7301/EMPHCN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 36359016 Biomolecules 2022
17 80.6 895 Cdataset Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Warfarin NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 Cdataset Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Chloroquine NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 PREDICT (Fdataset) Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Imatinib NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Imatinib NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Ziprasidone NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 Cdataset Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Fluconazole NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 Cdataset Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Citalopram NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 PREDICT (Fdataset) Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Ziprasidone NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 PREDICT (Fdataset) Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Chloroquine NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Warfarin NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Chloroquine NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 Cdataset Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Imatinib NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 PREDICT (Fdataset) Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Warfarin NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 PREDICT (Fdataset) Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Fluconazole NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 PREDICT (Fdataset) Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Citalopram NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Fluconazole NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Citalopram NA Top 5 diseases 31999326 Bioinformatics 2020
17 80.6 895 Cdataset Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) Bayesian inductive matrix Drug Disease Association (DDA) https://github.com/linwang1982/DRIMC Case studies NA NA Ziprasidone NA Top 5 diseases 31999326 Bioinformatics 2020
18 80.4 1670 LRSSL Drug, Disease Drug: SMILES, Disease: MeSH DRWBNCF Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/luckymengmeng/DRWBNCF Case studies Breast cancer NA NA NA Top 10 drugs 35039838 Brief Bioinform 2022
18 80.4 1670 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH DRWBNCF Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/luckymengmeng/DRWBNCF Case studies Breast cancer NA NA NA Top 10 drugs 35039838 Brief Bioinform 2022
18 80.4 1670 LRSSL Drug, Disease Drug: SMILES, Disease: MeSH DRWBNCF Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/luckymengmeng/DRWBNCF Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 10 drugs 35039838 Brief Bioinform 2022
18 80.4 1670 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH DRWBNCF Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/luckymengmeng/DRWBNCF Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 10 drugs 35039838 Brief Bioinform 2022
18 80.4 1670 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH DRWBNCF Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/luckymengmeng/DRWBNCF Case studies Breast cancer NA NA NA Top 10 drugs 35039838 Brief Bioinform 2022
18 80.4 1670 Cdataset Drug, Disease Drug: SMILES, Disease: MeSH DRWBNCF Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) Drug Disease Association (DDA) https://github.com/luckymengmeng/DRWBNCF Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 10 drugs 35039838 Brief Bioinform 2022
19 79.8 486 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Prednisolone NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Prednisolone NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Prednisolone NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Paclitaxel NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Paclitaxel NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Paclitaxel NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Zoledronic acid NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Zoledronic acid NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Zoledronic acid NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 DNdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 5 diseases 29365057 Bioinformatics 2018
19 79.8 486 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms DRRS (Drug Repositioning Recommendation System) Singular Value Thresholding (SVT) Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 5 diseases 29365057 Bioinformatics 2018
20 79.71428571 687 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Random Forest (RF) Drug Disease Association (DDA) NA Case studies NA NA Irinotecan NA Top 1 drug 31138103 BMC Bioinformatics 2019
20 79.71428571 687 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Random Forest (RF) Drug Disease Association (DDA) NA Case studies NA NA Cortisol NA Top 2 drugs 31138103 BMC Bioinformatics 2019
20 79.71428571 687 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Random Forest (RF) Drug Disease Association (DDA) NA Case studies NA NA Salicylic acid NA Top 1 drug 31138103 BMC Bioinformatics 2019
20 79.71428571 687 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Random Forest (RF) Drug Disease Association (DDA) NA Case studies NA NA Ephedrine NA Top 2 drugs 31138103 BMC Bioinformatics 2019
20 79.71428571 687 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Random Forest (RF) Drug Disease Association (DDA) NA Case studies NA NA Podophyllotoxin NA Top 1 drug 31138103 BMC Bioinformatics 2019
20 79.71428571 687 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Random Forest (RF) Drug Disease Association (DDA) NA Case studies NA NA Testosterone NA Top 3 drugs 31138103 BMC Bioinformatics 2019
20 79.71428571 687 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Random Forest (RF) Drug Disease Association (DDA) NA Case studies NA NA (-)-Prostaglandin E1 NA Top 1 drug 31138103 BMC Bioinformatics 2019
21 79.3 2179 Bdataset Drug, Disease, Target Drug: SMILES, Target: Sequence, Disease: MesH SiSGC (Simplifying Graph Convolution) CatBoost Drug Disease Association (DDA) https://github.com/MrPhil/SiSGC Case studies Breast neoplasms NA NA NA Top 20 drugs 38103039 J Chem Inf Model 2024
21 79.3 2179 Cdataset Drug, Disease, Target Drug: SMILES, Target: Sequence, Disease: MesH SiSGC (Simplifying Graph Convolution) CatBoost Drug Disease Association (DDA) https://github.com/MrPhil/SiSGC Case studies Breast neoplasms NA NA NA Top 20 drugs 38103039 J Chem Inf Model 2024
21 79.3 2179 Fdataset Drug, Disease, Target Drug: SMILES, Target: Sequence, Disease: MesH SiSGC (Simplifying Graph Convolution) CatBoost Drug Disease Association (DDA) https://github.com/MrPhil/SiSGC Case studies Breast neoplasms NA NA NA Top 20 drugs 38103039 J Chem Inf Model 2024
22 78.3 1615 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH HINGRL Random Forest (RF) Drug Disease Association (DDA) https://github.com/stevejobws/HINGRL Case studies NA Clozapine NA NA Top 10 diseases 34891172 Brief Bioinform 2022
22 78.3 1615 Fdataset Drug, Disease Drug: SMILES, Disease: MeSH HINGRL Random Forest (RF) Drug Disease Association (DDA) https://github.com/stevejobws/HINGRL Case studies Breast neoplasms NA NA NA Top 10 drugs 34891172 Brief Bioinform 2022
22 78.3 1615 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH HINGRL Random Forest (RF) Drug Disease Association (DDA) https://github.com/stevejobws/HINGRL Case studies NA Clozapine NA NA Top 10 diseases 34891172 Brief Bioinform 2022
22 78.3 1615 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH HINGRL Random Forest (RF) Drug Disease Association (DDA) https://github.com/stevejobws/HINGRL Case studies Breast neoplasms NA NA NA Top 10 drugs 34891172 Brief Bioinform 2022
23 78.1 2203 Cdataset Drug, Disease Chemical, Pharmacological, Therapeutic, Phenotypic, Genetic, Environment properties WMAGT Graph Convolutional Network,Graph Transformer,Neural Collaborative Filtering,Multilayer Perceptron Drug Disease Association (DDA) https://github.com/ShiHHe/WMAGT Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 38378479 BMC Bioinformatics 2024
23 78.1 2203 LRSSL Drug, Disease Chemical, Pharmacological, Therapeutic, Phenotypic, Genetic, Environment properties WMAGT Graph Convolutional Network,Graph Transformer,Neural Collaborative Filtering,Multilayer Perceptron Drug Disease Association (DDA) https://github.com/ShiHHe/WMAGT Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 38378479 BMC Bioinformatics 2024
23 78.1 2203 Fdataset Drug, Disease Chemical, Pharmacological, Therapeutic, Phenotypic, Genetic, Environment properties WMAGT Graph Convolutional Network,Graph Transformer,Neural Collaborative Filtering,Multilayer Perceptron Drug Disease Association (DDA) https://github.com/ShiHHe/WMAGT Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 38378479 BMC Bioinformatics 2024
24 78 1644 Fdataset Drug, Disease Drug: Chemical structure, Disease: MeSH NMF-DR (Non-negative Matrix Factorization Drug Repurposing) Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/sshaghayeghs/NMF-DR Case studies Breast cancer NA NA NA Top 5 drugs 34875000 Bioinformatics 2022
24 78 1644 TL-HBGI Drug, Disease Drug: Chemical structure, Disease: MeSH NMF-DR (Non-negative Matrix Factorization Drug Repurposing) Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/sshaghayeghs/NMF-DR Case studies Breast cancer NA NA NA Top 5 drugs 34875000 Bioinformatics 2022
24 78 1644 DrugNet Drug, Disease Drug: Chemical structure, Disease: MeSH NMF-DR (Non-negative Matrix Factorization Drug Repurposing) Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/sshaghayeghs/NMF-DR Case studies Breast cancer NA NA NA Top 5 drugs 34875000 Bioinformatics 2022
24 78 1644 Cdataset Drug, Disease Drug: Chemical structure, Disease: MeSH NMF-DR (Non-negative Matrix Factorization Drug Repurposing) Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/sshaghayeghs/NMF-DR Case studies Breast cancer NA NA NA Top 5 drugs 34875000 Bioinformatics 2022
25 77.875 509 TL-HGBI Drug, Target Drug: substructures, Disease: MeSH NTSIM (Network Topological Similarity-based Inference Method) Label Propagation Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 10 diseases 29879508 Methods 2018
25 77.875 509 LRSSL Drug, Disease Drug: substructures, Disease: MeSH NTSIM (Network Topological Similarity-based Inference Method) Label Propagation Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 10 diseases 29879508 Methods 2018
25 77.875 509 NA Drug, Disease Drug: substructures, Disease: MeSH NTSIM (Network Topological Similarity-based Inference Method) Label Propagation Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 10 diseases 29879508 Methods 2018
25 77.875 509 Fdataset Drug, Disease Drug: substructures, Disease: MeSH NTSIM (Network Topological Similarity-based Inference Method) Label Propagation Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 10 diseases 29879508 Methods 2018
26 77.76 766 LRSSL Drug, Disease, Side-effect Drug: chemical substructure, domains of target target, GO terms of drug target, Disease associated with the interested Drug, Drug side-effect; Disease: MeSH, Disease ontology DisDrugPred Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/pingxuan-hlju/DisDrugPred Case studies NA NA Etoposide NA Top 10 diseases 30865257 Bioinformatics 2019
26 77.76 766 LRSSL Drug, Disease, Side-effect Drug: chemical substructure, domains of target target, GO terms of drug target, Disease associated with the interested Drug, Drug side-effect; Disease: MeSH, Disease ontology DisDrugPred Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/pingxuan-hlju/DisDrugPred Case studies NA NA Cefotaxime NA Top 10 diseases 30865257 Bioinformatics 2019
26 77.76 766 LRSSL Drug, Disease, Side-effect Drug: chemical substructure, domains of target target, GO terms of drug target, Disease associated with the interested Drug, Drug side-effect; Disease: MeSH, Disease ontology DisDrugPred Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/pingxuan-hlju/DisDrugPred Case studies NA NA Ciprofloxacin NA Top 10 diseases 30865257 Bioinformatics 2019
26 77.76 766 LRSSL Drug, Disease, Side-effect Drug: chemical substructure, domains of target target, GO terms of drug target, Disease associated with the interested Drug, Drug side-effect; Disease: MeSH, Disease ontology DisDrugPred Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/pingxuan-hlju/DisDrugPred Case studies NA NA Clonidine NA Top 10 diseases 30865257 Bioinformatics 2019
26 77.76 766 LRSSL Drug, Disease, Side-effect Drug: chemical substructure, domains of target target, GO terms of drug target, Disease associated with the interested Drug, Drug side-effect; Disease: MeSH, Disease ontology DisDrugPred Non-negative Matrix Factorization (NMF) Drug Disease Association (DDA) https://github.com/pingxuan-hlju/DisDrugPred Case studies NA NA Ampicillin NA Top 10 diseases 30865257 Bioinformatics 2019
27 77.7 2133 LRSSL Drug, Disease NA DRAGNN Multi Layer Perception (MLP) Drug Disease Association (DDA) https://github.com/1yiw/DRAGNN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 38019732 Brief Bioinform 2023
27 77.7 2133 Fdataset Drug, Disease NA DRAGNN Multi Layer Perception (MLP) Drug Disease Association (DDA) https://github.com/1yiw/DRAGNN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 38019732 Brief Bioinform 2023
27 77.7 2133 Fdataset Drug, Disease NA DRAGNN Multi Layer Perception (MLP) Drug Disease Association (DDA) https://github.com/1yiw/DRAGNN Case studies Breast cancer NA NA NA Top 10 drugs 38019732 Brief Bioinform 2023
27 77.7 2133 LRSSL Drug, Disease NA DRAGNN Multi Layer Perception (MLP) Drug Disease Association (DDA) https://github.com/1yiw/DRAGNN Case studies Breast cancer NA NA NA Top 10 drugs 38019732 Brief Bioinform 2023
27 77.7 2133 Cdataset Drug, Disease NA DRAGNN Multi Layer Perception (MLP) Drug Disease Association (DDA) https://github.com/1yiw/DRAGNN Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 38019732 Brief Bioinform 2023
27 77.7 2133 Cdataset Drug, Disease NA DRAGNN Multi Layer Perception (MLP) Drug Disease Association (DDA) https://github.com/1yiw/DRAGNN Case studies Breast cancer NA NA NA Top 10 drugs 38019732 Brief Bioinform 2023
28 77.35 1367 Cdataset Drug, Disease Drug: SMILES, Disease: Phenotype DDIPred Deep gated recurrent units model Drug Disease Association (DDA) https://github.com/haichengyi/DDIPre Case studies NA NA Zoledronic acid NA Top 10 diseases 34074242 BMC Bioinformatics 2021
28 77.35 1367 Cdataset Drug, Disease Drug: SMILES, Disease: Phenotype DDIPred Deep gated recurrent units model Drug Disease Association (DDA) https://github.com/haichengyi/DDIPre Case studies NA NA Dexamethasone NA Top 15 diseases 34074242 BMC Bioinformatics 2021
28 77.35 1367 Fdataset Drug, Disease Drug: SMILES, Disease: Phenotype DDIPred Deep gated recurrent units model Drug Disease Association (DDA) https://github.com/haichengyi/DDIPre Case studies NA NA Zoledronic acid NA Top 10 diseases 34074242 BMC Bioinformatics 2021
28 77.35 1367 Fdataset Drug, Disease Drug: SMILES, Disease: Phenotype DDIPred Deep gated recurrent units model Drug Disease Association (DDA) https://github.com/haichengyi/DDIPre Case studies NA NA Dexamethasone NA Top 15 diseases 34074242 BMC Bioinformatics 2021
29 77.3 957 NA Drug, Disease, Target NA BiFusion (Bipartite graph convolution network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/zcwang0702/BiFusion Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 32657387 Bioinformatics 2020
29 77.3 957 NA Drug, Disease, Target NA BiFusion (Bipartite graph convolution network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/zcwang0702/BiFusion Case studies Breast carcinoma NA NA NA Top 5 drugs 32657387 Bioinformatics 2020
30 77.25 739 Fdataset Drug, Disease Drug: Fingerprint, Diseases: MeSH terms GIPAE (Gaussian interaction profile kernel and autoencoder) Deep Autoencoder,Support Vector Machine (SVM) Drug Disease Association (DDA) https://github.com/HanJingJiang/GIPAE Case studies Alzheimer's Disease (AD) NA NA NA Top 20 drug 31534955 Biomed Res Int 2019
30 77.25 739 Cdataset Drug, Disease Drug: Fingerprint, Diseases: MeSH terms GIPAE (Gaussian interaction profile kernel and autoencoder) Deep Autoencoder,Support Vector Machine (SVM) Drug Disease Association (DDA) https://github.com/HanJingJiang/GIPAE Case studies Obesity NA NA NA Top 20 drug 31534955 Biomed Res Int 2019
30 77.25 739 Cdataset Drug, Disease Drug: Fingerprint, Diseases: MeSH terms GIPAE (Gaussian interaction profile kernel and autoencoder) Deep Autoencoder,Support Vector Machine (SVM) Drug Disease Association (DDA) https://github.com/HanJingJiang/GIPAE Case studies Alzheimer's Disease (AD) NA NA NA Top 20 drug 31534955 Biomed Res Int 2019
30 77.25 739 Fdataset Drug, Disease Drug: Fingerprint, Diseases: MeSH terms GIPAE (Gaussian interaction profile kernel and autoencoder) Deep Autoencoder,Support Vector Machine (SVM) Drug Disease Association (DDA) https://github.com/HanJingJiang/GIPAE Case studies Obesity NA NA NA Top 20 drug 31534955 Biomed Res Int 2019
31 77.2 949 NA Drug, Disease, Target Drug: SMILES, Target: target sequence data in FASTA format Disease: MeSH TS-SVD Random Forest (RF) Drug Disease Association (DDA) NA Case studies Non-Small Cell Lung Cancer (NSCLC) NA NA NA Top 10 drugs 32340956 IEEE Trans Nanobioscience 2020
32 76.8 720 DNdataset Drug, Disease NA BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Doxorubicin NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 720 Cdataset Drug, Disease NA BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Doxorubicin NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 720 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Doxorubicin NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 1532 Cdataset Drug, Disease Drug: Chemical structure, Disease: MeSH LMFDA Inductive matrix Drug Disease Association (DDA) https://github.com/hupengwei/LMFDA_Dataset Case studies Type 2 Diabetes Mellitus (T2DM) NA NA NA Top 10 drugs 34736437 BMC Med Inform Decis Mak 2021
32 76.8 720 DNdataset Drug, Disease NA BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Amantadine NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 720 Cdataset Drug, Disease NA BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Amantadine NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 720 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Amantadine NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 1532 Cdataset Drug, Disease Drug: Chemical structure, Disease: MeSH LMFDA Inductive matrix Drug Disease Association (DDA) https://github.com/hupengwei/LMFDA_Dataset Case studies Ischemic stroke NA NA NA Top 10 drugs 34736437 BMC Med Inform Decis Mak 2021
32 76.8 1532 Fdataset Drug, Disease Drug: Chemical structure, Disease: MeSH LMFDA Inductive matrix Drug Disease Association (DDA) https://github.com/hupengwei/LMFDA_Dataset Case studies Type 2 Diabetes Mellitus (T2DM) NA NA NA Top 10 drugs 34736437 BMC Med Inform Decis Mak 2021
32 76.8 720 DNdataset Drug, Disease NA BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Flecainide NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 720 Cdataset Drug, Disease NA BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Flecainide NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 720 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Flecainide NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 720 Cdataset Drug, Disease NA BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Levodopa NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 1532 Fdataset Drug, Disease Drug: Chemical structure, Disease: MeSH LMFDA Inductive matrix Drug Disease Association (DDA) https://github.com/hupengwei/LMFDA_Dataset Case studies Ischemic stroke NA NA NA Top 10 drugs 34736437 BMC Med Inform Decis Mak 2021
32 76.8 720 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Levodopa NA Top 5 diseases 31510658 Bioinformatics 2019
32 76.8 720 DNdataset Drug, Disease NA BNNR (Bounded Nuclear Norm Regularization) Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/BNNR Case studies NA NA Levodopa NA Top 5 diseases 31510658 Bioinformatics 2019
33 76.54 1197 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Dexamethasone NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 Fdataset Drug, Disease Drug: SMILES; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Levofloxacin NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 SND Drug, Disease NA SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Loteprednol NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Triamcinolone NA Top 6 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Levofloxacin NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 Fdataset Drug, Disease Drug: SMILES; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Loteprednol NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 SND Drug, Disease NA SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Sparfloxacin NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 SND Drug, Disease NA SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Dexamethasone NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Loteprednol NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 Fdataset Drug, Disease Drug: SMILES; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Sparfloxacin NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 SND Drug, Disease NA SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Triamcinolone NA Top 6 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 Fdataset Drug, Disease Drug: SMILES; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Dexamethasone NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 SND Drug, Disease NA SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Levofloxacin NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 LRSSL Drug, Disease Drug: drug chemical structure, Pfam domain annotation of drug targets, gene ontology term of targets; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Sparfloxacin NA Top 7 diseases 33482713 BMC Bioinformatics 2021
33 76.54 1197 Fdataset Drug, Disease Drug: SMILES; Disease: Phenotye SNF-NN (Similarity network fusion and neural networks) Similarity Network Fusion (SNF),Neural Network Drug Disease Association (DDA) http://pages.cpsc.ucalgary.ca/ tnjarada/snf-nn.php Case studies NA NA Triamcinolone NA Top 6 diseases 33482713 BMC Bioinformatics 2021
34 76.425 2070 RepoDB Drug, Disease Drug: RDKit fingerprints, Disease: MeSH TNA-DR (Tail-Node Augmentation for Drug Repositioning) Graph Neural Network (GNN) Drug Disease Association (DDA) NA Case studies Lung neoplasms NA NA NA Top 10 drugs 37418410 IEEE/ACM Trans Comput Biol Bioinform 2023
34 76.425 2070 Fdataset Drug, Disease Drug: RDKit fingerprints, Disease: MeSH TNA-DR (Tail-Node Augmentation for Drug Repositioning) Graph Neural Network (GNN) Drug Disease Association (DDA) NA Case studies Lung neoplasms NA NA NA Top 10 drugs 37418410 IEEE/ACM Trans Comput Biol Bioinform 2023
34 76.425 2070 Cdataset Drug, Disease Drug: RDKit fingerprints, Disease: MeSH TNA-DR (Tail-Node Augmentation for Drug Repositioning) Graph Neural Network (GNN) Drug Disease Association (DDA) NA Case studies Lung neoplasms NA NA NA Top 10 drugs 37418410 IEEE/ACM Trans Comput Biol Bioinform 2023
34 76.425 2070 LRSSL Drug, Disease Drug: RDKit fingerprints, Disease: MeSH TNA-DR (Tail-Node Augmentation for Drug Repositioning) Graph Neural Network (GNN) Drug Disease Association (DDA) NA Case studies Lung neoplasms NA NA NA Top 10 drugs 37418410 IEEE/ACM Trans Comput Biol Bioinform 2023
35 76.1 1487 NA Drug, Gene NA GraphRepur Graph Neural Network (GNN) Drug Disease Association (DDA) https://github.com/cckamy/GraphRepur Case studies Breast cancer NA NA NA Top 30 drugs 33739367 Bioinformatics 2021
36 76 320 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms TP-NRWRH Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/td1799/TP-NRWRH Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 28155639 BMC Bioinformatics 2016
36 76 320 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms TP-NRWRH Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/td1799/TP-NRWRH Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 28155639 BMC Bioinformatics 2016
37 75 2066 DNdataset Drug, Disease Drug: SMILES, Disease: the medical description information SSLDR Matrix Factorization Drug Disease Association (DDA) NA Case studies NA NA Doxorubicin, Gemcitabine, Vincristine NA Top 5 diseases 37028367 IEEE/ACM Trans Comput Biol Bioinform 2023
37 75 2066 Fdataset Drug, Disease Drug: SMILES, Disease: the medical description information SSLDR Matrix Factorization Drug Disease Association (DDA) NA Case studies NA NA Doxorubicin, Gemcitabine, Vincristine NA Top 5 diseases 37028367 IEEE/ACM Trans Comput Biol Bioinform 2023
37 75 2066 Cdataset Drug, Disease Drug: SMILES, Disease: the medical description information SSLDR Matrix Factorization Drug Disease Association (DDA) NA Case studies NA NA Doxorubicin, Gemcitabine, Vincristine NA Top 5 diseases 37028367 IEEE/ACM Trans Comput Biol Bioinform 2023
38 74.9 1623 NA Drug Drug: chemical structures, Target: protein sequence DOTA (Drug repositioning approach using Optimal Transport for Alzheimer's disease) Deep Autoencoder (Multi-modal,Wasserstein variational) Drug Disease Association (DDA) https://github.com/fawer/DOTA Special studies Alzheimer's Disease (AD) NA NA NA Top 20 drugs 35204697 Biomolecules 2022
39 73.9 2102 DDKG-V1 Drug, Disease, Target, Gene NA DrugRep-HeSiaGraph Siamese Neural Network (SNN) Drug Disease Association (DDA) https://github.com/CBRC-lab/DrugRep-HeSiaGraph Case studies COVID-19 Dipeptidyl Peptidase 4 (DPP-4) NA NA Top 10 drugs 37789314 BMC Bioinformatics 2023
40 73.7 1366 NA Drug, Target Molecular descriptors NA Random Forest (RF) Drug Disease Association (DDA) https://github.com/sblab/DTN Special studies Hyperlipidemia NA NA NA Top 9 drugs 34030115 Comput Biol Chem 2021
40 73.7 1032 Fdataset Drug, Disease Drug: SMILES, Disease: Phenotye NEDD Random Forest (RF),Random Walk (RW) Drug Disease Association (DDA) NA Case studies NA NA NA Drug disease interaction Top 15 predictions 32938396 BMC Bioinformatics 2020
41 73.5 717 LRSSL Drug, Disease Drug: chemical substructure, chemical fingerprints, Disease: MeSH CBPred Convolutional Neural Network (CNN),Bidirectional Long Short-Term Memory (Bi-LSTM) Drug Disease Association (DDA) NA Case studies NA NA Ofloxacin NA Top 10 diseases 31336774 Cells 2019
41 73.5 717 LRSSL Drug, Disease Drug: chemical substructure, chemical fingerprints, Disease: MeSH CBPred Convolutional Neural Network (CNN),Bidirectional Long Short-Term Memory (Bi-LSTM) Drug Disease Association (DDA) NA Case studies NA NA Ampicillin NA Top 10 diseases 31336774 Cells 2019
41 73.5 717 LRSSL Drug, Disease Drug: chemical substructure, chemical fingerprints, Disease: MeSH CBPred Convolutional Neural Network (CNN),Bidirectional Long Short-Term Memory (Bi-LSTM) Drug Disease Association (DDA) NA Case studies NA NA Levofloxacin NA Top 10 diseases 31336774 Cells 2019
41 73.5 717 LRSSL Drug, Disease Drug: chemical substructure, chemical fingerprints, Disease: MeSH CBPred Convolutional Neural Network (CNN),Bidirectional Long Short-Term Memory (Bi-LSTM) Drug Disease Association (DDA) NA Case studies NA NA Ciprofloxacin NA Top 10 diseases 31336774 Cells 2019
41 73.5 717 LRSSL Drug, Disease Drug: chemical substructure, chemical fingerprints, Disease: MeSH CBPred Convolutional Neural Network (CNN),Bidirectional Long Short-Term Memory (Bi-LSTM) Drug Disease Association (DDA) NA Case studies NA NA Ceftriaxone NA Top 10 diseases 31336774 Cells 2019
42 72.35 812 NA Drug, Disease, Target , Side-effect NA deepDR Multimodal deep autoencoder (MDA),Collective variational autoencoder (cVAE),Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/ChengF-Lab/deepDR Case studies Parkinson’s Disease (PD) NA NA NA Top 20 drugs 31116390 Bioinformatics 2019
42 72.35 812 External validation set NA NA deepDR Multimodal deep autoencoder (MDA),Collective variational autoencoder (cVAE),Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/ChengF-Lab/deepDR Case studies Alzheimer's Disease (AD) NA NA NA Top 20 drugs 31116390 Bioinformatics 2019
42 72.35 812 External validation set NA NA deepDR Multimodal deep autoencoder (MDA),Collective variational autoencoder (cVAE),Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/ChengF-Lab/deepDR Case studies Parkinson’s Disease (PD) NA NA NA Top 20 drugs 31116390 Bioinformatics 2019
42 72.35 812 NA Drug, Disease, Target , Side-effect NA deepDR Multimodal deep autoencoder (MDA),Collective variational autoencoder (cVAE),Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/ChengF-Lab/deepDR Case studies Alzheimer's Disease (AD) NA NA NA Top 20 drugs 31116390 Bioinformatics 2019
43 72.3 125 NA Drug, Disease Drug: structure chemical, target, side-effect; Diseases: disease phenotypes, disease ontology, disease genes DDR Block Coordinate Descent (BCD) Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 25954437 AMIA Annu Symp Proc 2014
43 72.3 125 NA Drug, Disease Drug: structure chemical, target, side-effect; Diseases: disease phenotypes, disease ontology, disease genes DDR Block Coordinate Descent (BCD) Drug Disease Association (DDA) NA Case studies Systemic Lupus Erythematosus (SLE) NA NA NA Top 10 drugs 25954437 AMIA Annu Symp Proc 2014
44 72.15 2125 RepoDB Drug, Disease NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Rheumatoid arthritis NA NA NA Top 2 drugs 37925215 Artif Intell Med 2023
44 72.15 2125 NA Drug, Target, Pathway, Phenotype NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Congestive heart failure NA NA NA Top 2 drugs 37925215 Artif Intell Med 2023
44 72.15 2125 RepoDB Drug, Disease NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Left ventricular hypertrophy NA NA NA Top 1 drug 37925215 Artif Intell Med 2023
44 72.15 2125 NA Drug, Target, Pathway, Phenotype NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Rheumatoid arthritis NA NA NA Top 2 drugs 37925215 Artif Intell Med 2023
44 72.15 2125 NA Drug, Target, Pathway, Phenotype NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Left ventricular hypertrophy NA NA NA Top 1 drug 37925215 Artif Intell Med 2023
44 72.15 2125 RepoDB Drug, Disease NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Congestive heart failure NA NA NA Top 2 drugs 37925215 Artif Intell Med 2023
45 72.1 2022 KEGG Drug, Disease, Gene, Pathway Drug: ATC, Disease: MeSH DREAMwalk Multi-layer random walk Drug Disease Association (DDA) https://github.com/eugenebang/DREAMwalk Case studies Breast cancer NA NA NA Top 10 drugs 37322032 Nat Commun 2023
45 72.1 2022 Multi-scale interactome (MSI) network Drug, Disease, Gene Drug: ATC, Disease: MeSH DREAMwalk Multi-layer random walk Drug Disease Association (DDA) https://github.com/eugenebang/DREAMwalk Case studies Breast cancer NA NA NA Top 10 drugs 37322032 Nat Commun 2023
45 72.1 2022 KEGG Drug, Disease, Gene, Pathway Drug: ATC, Disease: MeSH DREAMwalk Multi-layer random walk Drug Disease Association (DDA) https://github.com/eugenebang/DREAMwalk Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 37322032 Nat Commun 2023
45 72.1 2022 Multi-scale interactome (MSI) network Drug, Disease, Gene Drug: ATC, Disease: MeSH DREAMwalk Multi-layer random walk Drug Disease Association (DDA) https://github.com/eugenebang/DREAMwalk Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 37322032 Nat Commun 2023
45 72.1 1244 NA Drug, Disease Drug: chemical structural, CMLDR Collaborative metric learning algorithm Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 20 diseases 31283509 IEEE/ACM Trans Comput Biol Bioinform 2021
45 72.1 2022 HetioNet Drug, Disease, Gene, Pathway Drug: ATC, Disease: MeSH DREAMwalk Multi-layer random walk Drug Disease Association (DDA) https://github.com/eugenebang/DREAMwalk Case studies Breast cancer NA NA NA Top 10 drugs 37322032 Nat Commun 2023
45 72.1 1244 NA Drug, Disease Drug: chemical structural, CMLDR Collaborative metric learning algorithm Drug Disease Association (DDA) NA Case studies NA NA Cyclophosphamide NA Top 20 diseases 31283509 IEEE/ACM Trans Comput Biol Bioinform 2021
45 72.1 2022 HetioNet Drug, Disease, Gene, Pathway Drug: ATC, Disease: MeSH DREAMwalk Multi-layer random walk Drug Disease Association (DDA) https://github.com/eugenebang/DREAMwalk Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 37322032 Nat Commun 2023
46 71.75 424 NA Drug, Disease, Gene Drug: SMILES, Disease: MeSH SSGC (Semi-Supervised Graph Cut) Semi-supervised graph cut Drug Disease Association (DDA) NA Case studies Huntington Disease (HD) NA NA NA Top 20 drugs 29297383 BMC Med Genomics 2017
46 71.75 424 NA Drug, Disease, Gene Drug: SMILES, Disease: MeSH SSGC (Semi-Supervised Graph Cut) Semi-supervised graph cut Drug Disease Association (DDA) NA Case studies Non-Small Cell Lung Cancer (NSCLC) NA NA NA Top 20 drugs 29297383 BMC Med Genomics 2017
46 71.75 424 NA Drug, Disease, Gene Drug: SMILES, Disease: MeSH SSGC (Semi-Supervised Graph Cut) Semi-supervised graph cut Drug Disease Association (DDA) NA Case studies Alcohol dependence NA NA NA Top 20 drugs 29297383 BMC Med Genomics 2017
46 71.75 424 NA Drug, Disease, Gene Drug: SMILES, Disease: MeSH SSGC (Semi-Supervised Graph Cut) Semi-supervised graph cut Drug Disease Association (DDA) NA Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 20 drugs 29297383 BMC Med Genomics 2017
47 71.7 771 Fdataset Drug, Disease Drug: SMILES, Proten: the amino acid sequence, Diseases: MeSH terms RWHNDR (Random Walk on a Heterogeneous Network for Drug Repositioning) Random Walk Drug Disease Association (DDA) NA Case studies Breast cancer NA NA NA Top 5 drugs 29994051 IEEE/ACM Trans Comput Biol Bioinform 2019
47 71.7 771 Fdataset Drug, Disease Drug: SMILES, Proten: the amino acid sequence, Diseases: MeSH terms RWHNDR (Random Walk on a Heterogeneous Network for Drug Repositioning) Random Walk Drug Disease Association (DDA) NA Case studies Lung cancer NA NA NA Top 5 drugs 29994051 IEEE/ACM Trans Comput Biol Bioinform 2019
47 71.7 771 Fdataset Drug, Disease Drug: SMILES, Proten: the amino acid sequence, Diseases: MeSH terms RWHNDR (Random Walk on a Heterogeneous Network for Drug Repositioning) Random Walk Drug Disease Association (DDA) NA Case studies Huntington Disease (HD) NA NA NA Top 5 drugs 29994051 IEEE/ACM Trans Comput Biol Bioinform 2019
47 71.7 771 Fdataset Drug, Disease Drug: SMILES, Proten: the amino acid sequence, Diseases: MeSH terms RWHNDR (Random Walk on a Heterogeneous Network for Drug Repositioning) Random Walk Drug Disease Association (DDA) NA Case studies Parkinson’s Disease (PD) NA NA NA Top 5 drugs 29994051 IEEE/ACM Trans Comput Biol Bioinform 2019
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Yohimbine NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Thiopental NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Tacrolimus NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Tolmetin NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Ziprasidone NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Fenoprofen NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Nimodipine NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Citalopram NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Progesterone NA Top 5 diseases 28096083 Bioinformatics 2017
48 71.04 361 LRSSL Drug, Disease Drug: chemical fingerprints, target target domain, target gene ontology annotation; Disease: MeSH LRSSL (Laplacian regularized sparse subspace learning) Laplacian regularized sparse subspace learning Drug Disease Association (DDA) https://github.com/LiangXujun/LRSSL Case studies NA NA Dextromethorphan NA Top 5 diseases 28096083 Bioinformatics 2017
49 70.9 1796 Zhang's dataset Drug, Disease Drug: SMILES, Disease: Mesh semantic GraphPK (Graph-based Prior Knowledge) Multimodal neural network Drug Disease Association (DDA) NA Case studies NA NA NA Drug disease interaction Top 10 predictions 34375284 IEEE/ACM Trans Comput Biol Bioinform 2022
49 70.9 1796 Zhang's dataset Drug, Disease Drug: SMILES, Disease: Mesh semantic GraphPK (Graph-based Prior Knowledge) Multimodal neural network Drug Disease Association (DDA) NA Case studies NA NA NA Drug disease interaction Top 10 predictions 34375284 IEEE/ACM Trans Comput Biol Bioinform 2022
49 70.9 1796 Amazon's dataset Drug, Disease Drug: SMILES, Disease: Mesh semantic GraphPK (Graph-based Prior Knowledge) Multimodal neural network Drug Disease Association (DDA) NA Case studies NA NA NA Drug disease interaction Top 10 predictions 34375284 IEEE/ACM Trans Comput Biol Bioinform 2022
50 70.85 1798 dataset 1 Drug, Disease, Gene NA NEDNBI Network-Based Inference Drug Disease Association (DDA) https://github.com/Qli97/NEDNBI Case studies COVID-19 NA NA NA Top 20 drugs 35338586 Mol Inform 2022
50 70.85 1798 dataset 2 Drug, Disease, Gene NA NEDNBI Network-Based Inference Drug Disease Association (DDA) https://github.com/Qli97/NEDNBI Case studies COVID-19 NA NA NA Top 20 drugs 35338586 Mol Inform 2022
51 70.8 1516 Zhang's book Drug, Disease Drug: chemical structure, side-effect; Disease: UMLS DRDA Deep Autoencoder,Adaptive Fusion Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 34717542 BMC Bioinformatics 2021
51 70.8 1516 Zhang's book Drug, Target Drug: chemical structure, side-effect; Disease: UMLS DRDA Deep Autoencoder,Adaptive Fusion Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 34717542 BMC Bioinformatics 2021
51 70.8 1516 Zhang's book Side-effect Drug: chemical structure, side-effect; Disease: UMLS DRDA Deep Autoencoder,Adaptive Fusion Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 34717542 BMC Bioinformatics 2021
52 70.4 1866 Fdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH, Target: sequence DDAGDL Geometric Deep Learning (GDL),XGBoost Drug Disease Association (DDA) https://github.com/stevejobws/DDAGDL Case studies Breast cancer NA NA NA Top 10 drugs 36125202 Brief Bioinform 2022
52 70.4 1866 Bdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH, Target: sequence DDAGDL Geometric Deep Learning (GDL),XGBoost Drug Disease Association (DDA) https://github.com/stevejobws/DDAGDL Case studies Breast cancer NA NA NA Top 10 drugs 36125202 Brief Bioinform 2022
52 70.4 1866 Cdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH, Target: sequence DDAGDL Geometric Deep Learning (GDL),XGBoost Drug Disease Association (DDA) https://github.com/stevejobws/DDAGDL Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 36125202 Brief Bioinform 2022
52 70.4 1866 Cdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH, Target: sequence DDAGDL Geometric Deep Learning (GDL),XGBoost Drug Disease Association (DDA) https://github.com/stevejobws/DDAGDL Case studies Breast cancer NA NA NA Top 10 drugs 36125202 Brief Bioinform 2022
52 70.4 1866 Fdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH, Target: sequence DDAGDL Geometric Deep Learning (GDL),XGBoost Drug Disease Association (DDA) https://github.com/stevejobws/DDAGDL Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 36125202 Brief Bioinform 2022
52 70.4 1866 Bdataset Drug, Disease, Target Drug: SMILES, Disease: MeSH, Target: sequence DDAGDL Geometric Deep Learning (GDL),XGBoost Drug Disease Association (DDA) https://github.com/stevejobws/DDAGDL Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 36125202 Brief Bioinform 2022
53 70.1 789 NA Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Non-linear computational approach Drug Disease Association (DDA) http://bioinformatics.aut.ac.ir/drug-disc/ (Data) Case studies NA NA NA Drug disease interaction Top 16 predictions 31726977 BMC Bioinformatics 2019
54 70 14 Fdataset Drug, Disease Drug: SMILES, Gene sequence , GO, side-effect, PPI network; Diseases: MeSH, Genetic PREDICT (PREdicting Drug IndiCaTions) Logistic Regression Drug Disease Association (DDA) NA Case studies Migrane NA NA NA 1 drug 21654673 Mol Syst Biol 2011
54 70 14 Fdataset Drug, Disease Drug: SMILES, Gene sequence , GO, side-effect, PPI network; Diseases: MeSH, Genetic PREDICT (PREdicting Drug IndiCaTions) Logistic Regression Drug Disease Association (DDA) NA Case studies Non-papillary renal cell cancer NA NA NA 1 drug 21654673 Mol Syst Biol 2011
55 69.8 2160 DrugRepV Drug Drug: SMILES, Anti-Dengue Support Vector Machine (SVM),Artificial Neural Network (ANN),k-Nearest Neighbor (kNN),Random Forest (RF) Drug Disease Association (DDA) NA Special studies Dengue NA NA NA Top 25 drugs 38257744 Viruses 2023
56 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Polysubstance abuse NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
56 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Huntington Disease (HD) NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
56 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Non-Small Cell Lung Cancer (NSCLC) NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
56 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Alcohol dependence NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
56 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
57 69.1 1913 drug ECR Drug, Disease NA DRONet Network embedding (NE) Drug Disease Association (DDA) https://github.com/yangkuoone/DRONet Case studies Diabetes NA NA NA Top 10 drugs 36562715 Brief Bioinform 2023
58 68.9 2098 NA Drug, Disease, Target, miRNA NA MTLDR (Multi-task learning framework for drug repurposing) Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 37516260 Methods 2023
58 68.9 2098 NA Drug, Disease, Target, miRNA NA MTLDR (Multi-task learning framework for drug repurposing) Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies Tourette's Syndrome NA NA NA Top 10 drugs 37516260 Methods 2023
59 68.8 2167 OpenBioLink Drug, Disease, Target NA MPTN CompGCN,Transformer,InteractE Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 38043469 Comput Biol Med 2024
59 68.8 2167 GP-KG Drug, Disease, Gene NA MPTN CompGCN,Transformer,InteractE Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 38043469 Comput Biol Med 2024
60 68.5 672 NA Gene, Celllines NA NA Deep neural Network (DNN),Support Vector Machine (SVM),Random Forest (RF),Gradient Boosted Machine with trees (GBM),logistic regression with elastic net regularization (EN) Drug Disease Association (DDA) NA Special studies Depressive Disorder NA NA NA Top 8 drugs 30010603 IEEE J Biomed Health Inform 2019
60 68.5 1768 NA Drug, Disease, Target NA NTD-DR Nonnegative tensor decomposition Drug Disease Association (DDA) https://github.com/AliJam82/NTD-DR Case studies Breast ductal carcinoma, Prostate cancer, Pancreatic neoplasms, Colorectal neoplasms, Small cell lung carcinoma NA NA NA Top 50 drugs 35862409 PLoS One 2022
60 68.5 672 NA Gene, Celllines NA NA Deep neural Network (DNN),Support Vector Machine (SVM),Random Forest (RF),Gradient Boosted Machine with trees (GBM),logistic regression with elastic net regularization (EN) Drug Disease Association (DDA) NA Special studies Schizophrenia NA NA NA Top 8 drugs 30010603 IEEE J Biomed Health Inform 2019
61 68.2 192 NA Drug, Disease Disease: Phenotypic terms PhenoPredict The iterative network-based ranking algorithm Drug Disease Association (DDA) NA Special studies Schizophrenia NA NA NA Top 20 drugs 26151312 J Biomed Inform 2015
62 68.1 467 NA Drug, Target, Side-effect Drug: chemical properties, target targets, side-effect NA Pareto dominance,Collaborative filtering Drug Disease Association (DDA) NA NA NA NA NA Drug disease interaction Top 20 predictions 29649971 BMC Bioinformatics 2018
63 67.8 2015 NA Drug, Gene NA DTSEA (Drug Target Set Enrichment Analysis) Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/hanjunwei-lab/DTSEAData Special studies COVID-19 NA NA NA Top 10 drugs 37105108 Comput Biol Med 2023
64 67 1937 Gottlieb dataset (Fdataset) Drug, Disease Drug: SMILES, Disease: the medical description PUON Matrix Factorization Drug Disease Association (DDA) NA Case studies NA Doxorubicin, Gemcitabine, Vincristine, Methotrexate, Risperidone NA NA Top 5 diseases 36197871 IEEE/ACM Trans Comput Biol Bioinform 2023
64 67 1021 NA Drug, Disease, miRNA Drug: chemical structure, side-effect, functional consistency; miRNA: target genes, disease targets; Disease: MeSH BIMC Bilateral-inductive matrix completion (BIMC) Drug Disease Association (DDA) https://github.com/Deepthi-K523/BIMC Case studies NA NA Almitrine NA Top 10 diseases 32583015 Mol Genet Genomics 2020
64 67 1937 Cdataset Drug, Disease Drug: SMILES, Disease: the medical description PUON Matrix Factorization Drug Disease Association (DDA) NA Case studies NA Doxorubicin, Gemcitabine, Vincristine, Methotrexate, Risperidone NA NA Top 5 diseases 36197871 IEEE/ACM Trans Comput Biol Bioinform 2023
64 67 1021 NA Drug, Disease, miRNA Drug: chemical structure, side-effect, functional consistency; miRNA: target genes, disease targets; Disease: MeSH BIMC Bilateral-inductive matrix completion (BIMC) Drug Disease Association (DDA) https://github.com/Deepthi-K523/BIMC Case studies NA NA Aminolevulinic acid NA Top 10 diseases 32583015 Mol Genet Genomics 2020
64 67 1937 DNdataset Drug, Disease Drug: SMILES, Disease: the medical description PUON Matrix Factorization Drug Disease Association (DDA) NA Case studies NA Doxorubicin, Gemcitabine, Vincristine, Methotrexate, Risperidone NA NA Top 5 diseases 36197871 IEEE/ACM Trans Comput Biol Bioinform 2023
64 67 1937 Ldataset Drug, Disease Drug: SMILES, Disease: the medical description PUON Matrix Factorization Drug Disease Association (DDA) NA Case studies NA Doxorubicin, Gemcitabine, Vincristine, Methotrexate, Risperidone NA NA Top 5 diseases 36197871 IEEE/ACM Trans Comput Biol Bioinform 2023
65 66.65 1973 RepoDB Drug, Disease NA DrugRep-KG Logistic Regression Drug Disease Association (DDA) https://github.com/CBRC-lab/DrugRep-KG Case studies COVID-19 NA NA NA Top 6 drugs 37023229 J Chem Inf Model 2023
65 66.65 1973 Negative set Drug, Disease NA DrugRep-KG Logistic Regression Drug Disease Association (DDA) https://github.com/CBRC-lab/DrugRep-KG Case studies Atopic Eczema NA NA NA Top 4 drugs 37023229 J Chem Inf Model 2023
65 66.65 1973 Negative set Drug, Disease NA DrugRep-KG Logistic Regression Drug Disease Association (DDA) https://github.com/CBRC-lab/DrugRep-KG Case studies Contact Dermatitis NA NA NA Top 2 drugs 37023229 J Chem Inf Model 2023
65 66.65 1973 RepoDB Drug, Disease NA DrugRep-KG Logistic Regression Drug Disease Association (DDA) https://github.com/CBRC-lab/DrugRep-KG Case studies Atopic Eczema NA NA NA Top 4 drugs 37023229 J Chem Inf Model 2023
65 66.65 1973 RepoDB Drug, Disease NA DrugRep-KG Logistic Regression Drug Disease Association (DDA) https://github.com/CBRC-lab/DrugRep-KG Case studies Contact Dermatitis NA NA NA Top 2 drugs 37023229 J Chem Inf Model 2023
65 66.65 1973 Negative set Drug, Disease NA DrugRep-KG Logistic Regression Drug Disease Association (DDA) https://github.com/CBRC-lab/DrugRep-KG Case studies COVID-19 NA NA NA Top 6 drugs 37023229 J Chem Inf Model 2023
66 66.4 1990 PREDICT (Fdataset) Drug, Disease NA NetPro Label Propagation Drug Disease Association (DDA) https://github.com/hyr0771/NetPro Case studies NA NA Levodopa, Flecainide, Doxorubicin NA Top 5 diseases 37018341 IEEE/ACM Trans Comput Biol Bioinform 2023
66 66.4 1990 Cdataset Drug, Disease NA NetPro Label Propagation Drug Disease Association (DDA) https://github.com/hyr0771/NetPro Case studies NA NA Levodopa, Flecainide, Doxorubicin NA Top 5 diseases 37018341 IEEE/ACM Trans Comput Biol Bioinform 2023
66 66.4 1990 LRSSL Drug, Disease NA NetPro Label Propagation Drug Disease Association (DDA) https://github.com/hyr0771/NetPro Case studies NA NA Levodopa, Flecainide, Doxorubicin NA Top 5 diseases 37018341 IEEE/ACM Trans Comput Biol Bioinform 2023
67 65.6 573 Fdataset Drug, Disease Drug: chemical substructures, Disease: MeSH RLSDR (Regularized Least Square for Drug Repositioning) Regularized Least Square Drug Disease Association (DDA) NA Case studies NA NA NA Drug disease interaction Top 19 predictions 29700660 Acta Biotheor 2018
67 65.6 573 Fdataset Drug, Disease Drug: chemical substructures, Disease: MeSH RLSDR (Regularized Least Square for Drug Repositioning) Regularized Least Square Drug Disease Association (DDA) NA Case studies NA NA NA Drug disease interaction Top 19 predictions 29700660 Acta Biotheor 2018
67 65.6 573 DNdataset Drug, Disease NA RLSDR (Regularized Least Square for Drug Repositioning) Regularized Least Square Drug Disease Association (DDA) NA Case studies NA NA NA Drug disease interaction Top 19 predictions 29700660 Acta Biotheor 2018
68 64.8 1814 NA Drug, chemical NA NA Knowledge Graph Embedding Drug Disease Association (DDA) NA Special studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 36180861 BMC Bioinformatics 2022
69 63.2 356 Yamanishi_NR Drug, Target Drug: chemical sturcture, Target: target sequence Heter-LP Heterogeneous label propagation Drug Target Interaction (DTI),Drug Disease Association (DDA) NA Case studies Osteoarthritis with mild chondrodysplasia NA NA NA 2 drugs 28300647 J Biomed Inform 2017
69 63.2 356 NA Drug, Disease, Target NA Heter-LP Heterogeneous label propagation Drug Target Interaction (DTI),Drug Disease Association (DDA) NA Case studies Osteoarthritis with mild chondrodysplasia NA NA NA 2 drugs 28300647 J Biomed Inform 2017
69 63.2 356 Yamanishi_E Drug, Target Drug: chemical sturcture, Target: target sequence Heter-LP Heterogeneous label propagation Drug Target Interaction (DTI),Drug Disease Association (DDA) NA Case studies Osteoarthritis with mild chondrodysplasia NA NA NA 2 drugs 28300647 J Biomed Inform 2017
69 63.2 356 Yamanishi_IC Drug, Target Drug: chemical sturcture, Target: target sequence Heter-LP Heterogeneous label propagation Drug Target Interaction (DTI),Drug Disease Association (DDA) NA Case studies Osteoarthritis with mild chondrodysplasia NA NA NA 2 drugs 28300647 J Biomed Inform 2017
69 63.2 356 Yamanishi_GPCR Drug, Target Drug: chemical sturcture, Target: target sequence Heter-LP Heterogeneous label propagation Drug Target Interaction (DTI),Drug Disease Association (DDA) NA Case studies Osteoarthritis with mild chondrodysplasia NA NA NA 2 drugs 28300647 J Biomed Inform 2017
70 62.9 36 NA Drug, Disease, Target, Gene, Pathway NA CauseNet Computing transition weights Drug Disease Association (DDA) NA Case studies Crohn's disease (CD) NA NA NA Top 5 drugs 24564553 BMC Bioinformatics 2013
71 62.5 736 Cdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms ANMF Additional Neural Matrix Factorization Drug Disease Association (DDA) https://github.com/MortySn/ANMF NA NA NA NA NA NA 31412762 BMC Bioinformatics 2019
71 62.5 736 Fdataset Drug, Disease Drug: SMILES, Diseases: MeSH terms ANMF Additional Neural Matrix Factorization Drug Disease Association (DDA) https://github.com/MortySn/ANMF NA NA NA NA NA NA 31412762 BMC Bioinformatics 2019
72 60.6 2208 NELL-One NA NA MLAN (Multi-Level Attention Network) Gated Mechanism,Attention Mechanism,MTransD,Commonality Relation Learner (CRL) Drug Disease Association (DDA) NA Case studies COVID-19 NA NA NA Top 5 drugs 38244473 Comput Biol Med 2024
72 60.6 2208 BIOKG-One Drug, Disease, Target, Side-effect, NA MLAN (Multi-Level Attention Network) Gated Mechanism,Attention Mechanism,MTransD,Commonality Relation Learner (CRL) Drug Disease Association (DDA) NA Case studies COVID-19 NA NA NA Top 5 drugs 38244473 Comput Biol Med 2024
72 60.6 2208 COVID19-One NA NA MLAN (Multi-Level Attention Network) Gated Mechanism,Attention Mechanism,MTransD,Commonality Relation Learner (CRL) Drug Disease Association (DDA) NA Case studies COVID-19 NA NA NA Top 5 drugs 38244473 Comput Biol Med 2024
73 60.5 1980 Ovarian Cancer Dataset Drug, Gene NA SPLNMTF (Self-Paced Non-negative Matrix Tri-Factorization) Matrix Factorization Drug Disease Association (DDA) https://github.com/qi0906/SPLNMTF NA NA NA NA NA NA 36445996 IEEE/ACM Trans Comput Biol Bioinform 2023
73 60.5 1980 Acute myeloid leukemia (AML) dataset Drug, Gene NA SPLNMTF (Self-Paced Non-negative Matrix Tri-Factorization) Matrix Factorization Drug Disease Association (DDA) https://github.com/qi0906/SPLNMTF NA NA NA NA NA NA 36445996 IEEE/ACM Trans Comput Biol Bioinform 2023
74 59.9 1060 NA Drug, Disease, Target, Gene NA RepCOOL Random Forest (RF) Drug Disease Association (DDA) NA Case studies Breast cancer stage II NA NA NA Top 4 drugs 33008415 J Transl Med 2020
75 59.7 1140 NA Chemical molecules, Gene, Gene expression profiles NA MNBDR (Module Network Ba​​sed Drug Repositioning）LINC1000,Cmap Random Walk Drug Disease Association (DDA) https://github.com/nbnbhwyy/MNBDR Case studies Breast cancer NA NA NA NA 33375395 Genes (Basel) 2020
75 59.7 1140 Golden standard Drug, Disease NA MNBDR (Module Network Ba​​sed Drug Repositioning）LINC1000,Cmap Random Walk Drug Disease Association (DDA) https://github.com/nbnbhwyy/MNBDR Case studies Breast cancer NA NA NA NA 33375395 Genes (Basel) 2020
76 59.2 140 Fdataset Drug, Disease NA NA ProbS and HeatS Drug Disease Association (DDA) NA Case studies NA NA Aspirin NA Top 10 diseases 25969690 Comput Math Methods Med 2015
76 59.2 140 Fdataset Drug, Disease NA NA ProbS and HeatS Drug Disease Association (DDA) NA Case studies NA NA Tamoxifen NA Top 10 diseases 25969690 Comput Math Methods Med 2015
76 59.2 140 Fdataset Drug, Disease NA NA ProbS and HeatS Drug Disease Association (DDA) NA Case studies NA NA Felodipine NA Top 10 diseases 25969690 Comput Math Methods Med 2015
77 58.9 1260 NA Subject, object, predicate NA LBD Knowledge Graph Completion Drug Disease Association (DDA) https://github.com/kilicogluh/lbd-covid Special studies COVID-19 NA NA NA 5 drugs 33571675 J Biomed Inform 2021
78 58.5 1132 Fdataset Drug, Disease Drug: SMILES, Disease: medical description data HAMN (Hybrid Attentional Memory Network) Collaborative Filtering,Autoencoder Drug Disease Association (DDA) NA NA NA NA NA NA NA 33297947 BMC Bioinformatics 2020
78 58.5 1132 Cdataset Drug, Disease Drug: SMILES, Disease: medical description data HAMN (Hybrid Attentional Memory Network) Collaborative Filtering,Autoencoder Drug Disease Association (DDA) NA NA NA NA NA NA NA 33297947 BMC Bioinformatics 2020
79 56.5 1546 NA Drug, Disease, Gene NA GCAN (GRU-Cooperation-Attention-Network) GRU-Cooperation-Attention-Network (GCAN),RNN,Biased random walk Drug Disease Association (DDA) NA Case studies type I Gaucher disease NA NA NA Top 2 drugs 34789254 BMC Med Inform Decis Mak 2021
80 55.4 1915 NA Drug, Gene NA NA Random Walk with Restart (RWR) Drug Disease Association (DDA) NA Special studies Colorectal Cancer NA NA NA Top 9 drugs 36768566 Int J Mol Sci 2023
80 55.4 1915 NA Drug, Gene NA NA Random Walk with Restart (RWR) Drug Disease Association (DDA) NA Special studies Non-Small Cell Lung Cancer (NSCLC) NA NA NA Top 11 drugs 36768566 Int J Mol Sci 2023
81 53.5 475 Dataset 1 Drug, Disease Drug: drug substructures, target target functional domain and GO annotations, Diseases: MeSH terms DR2DI Regularized Kernel Classifier Drug Disease Association (DDA) https://github.com/huayu1111/DR2DI NA NA NA NA NA NA 29687309 J Comput Aided Mol Des 2018
81 53.5 586 NA Drug, Disease Drug: PubChem fingerprints, Disease: MeSH DrPOCS (projection onto convex sets) Matrix Completion Drug Disease Association (DDA) NA NA NA NA NA NA NA 29993698 IEEE/ACM Trans Comput Biol Bioinform 2019
81 53.5 2169 DRKG Drug, Disease, Gene, Pathway, Side-effect, Compound, Anatomy, Tax, Molecular Function, Symptom, Biological Process, Cellular Component, Atc, PharmacologicClass NA TransRGNN Graph Neural Network (GNN) Drug Disease Association (DDA) NA Case studies COVID-19 NA NA NA Top 30 drugs 38104883 Methods 2024
82 53 856 LRSSL Drug, Disease Drug: chemical structure, drug target domain, drug target gene ontology (GO); Disease: semantic DDAPRED Logistic Matrix Factorization Drug Disease Association (DDA) https://github.com/nongdaxiaofeng/DDAPRED NA NA NA NA NA NA 32062701 J Mol Model 2020
83 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Chronic lymphocytic leukemia NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
83 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Dysmenorrhea NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
83 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Psoriasis NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
83 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Urticaria NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
83 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Osteoarthritis NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
84 49 559 MULAN Drug, Disease, Gene Chemical: Extended Connectivity Fingerprint (ECFP), Gene: amino acid sequence ANTENNA Dual-regularized weighted,Imputed One Class Collaborative Filtering (OCCF) algorithm,Random Walk Restart Drug Disease Association (DDA) NA NA NA NA NA NA NA 29993812 IEEE/ACM Trans Comput Biol Bioinform 2018
84 49 64 Fdataset Drug, Disease Drug: structure chemical, target, side-effect, Diseases: MeSH terms PreDR (Predict Drug Repositioning) Support Vector Machine (SVM) Drug Disease Association (DDA) NA NA NA NA NA NA NA 24244318 PLoS One 2013
85 47.5 1795 NA Drug, Disease, Target, Side-effect, Substructure NA MGATRx Graph Neural Network (GNN) Drug Disease Association (DDA) https://github.com/yellajaswanth/MGATRx NA NA NA NA NA NA 34014830 IEEE/ACM Trans Comput Biol Bioinform 2022
86 46.75 2132 Fdataset Drug, Disease NA IDDI-DNN Convolutional Neural Network (CNN) Drug Disease Association (DDA) NA NA NA NA NA NA NA 37993777 BMC Bioinformatics 2023
86 46.75 2132 DNdataset Drug, Disease NA IDDI-DNN Convolutional Neural Network (CNN) Drug Disease Association (DDA) NA NA NA NA NA NA NA 37993777 BMC Bioinformatics 2023
87 45 1220 NA Drug, Disease, Gene NA SAveRUNNER (Searching off-lAbel dRUg aNd NEtwoRk) Bi-Random walk-based algorithm Drug Disease Association (DDA) NA NA NA NA NA NA NA 33544720 PLoS Comput Biol 2021
88 44.5 1851 DRKG Drug, Disease, Gene, Anatomies NA GDRnet Graph Neural Network (GNN) Drug Disease Association (DDA) https://github.com/siddhant-doshi/GDRnet Case studies NA NA NA NA NA 36228466 Comput Biol Med 2022
89 44 1886 Cdataset Drug, Disease NA NMFDR (Neural Metric Factorization model for computational Drug Repositioning) Matrix Factorization Drug Disease Association (DDA) NA NA NA NA NA NA NA 35061591 IEEE/ACM Trans Comput Biol Bioinform 2023
89 44 1886 DNdataset Drug, Disease NA NMFDR (Neural Metric Factorization model for computational Drug Repositioning) Matrix Factorization Drug Disease Association (DDA) NA NA NA NA NA NA NA 35061591 IEEE/ACM Trans Comput Biol Bioinform 2023
89 44 1886 Fdataset Drug, Disease NA NMFDR (Neural Metric Factorization model for computational Drug Repositioning) Matrix Factorization Drug Disease Association (DDA) NA NA NA NA NA NA NA 35061591 IEEE/ACM Trans Comput Biol Bioinform 2023
90 42.5 1935 RepoDB (RDB) Drug, Disease, Gene NA NA Biased random walks Drug Disease Association (DDA) NA Case studies Rheumatoid Arthritis NA NA NA 1 drug 35839194 IEEE/ACM Trans Comput Biol Bioinform 2023
90 42.5 1935 DrugBank Drug, Disease, Gene NA NA Biased random walks Drug Disease Association (DDA) NA Case studies Rheumatoid Arthritis NA NA NA 1 drug 35839194 IEEE/ACM Trans Comput Biol Bioinform 2023
90 42.5 1935 iDrug (ID) Drug, Disease, Gene NA NA Biased random walks Drug Disease Association (DDA) NA Case studies Rheumatoid Arthritis NA NA NA 1 drug 35839194 IEEE/ACM Trans Comput Biol Bioinform 2023
90 42.5 1935 DisGeNET (DGN) Drug, Disease, Gene NA NA Biased random walks Drug Disease Association (DDA) NA Case studies Rheumatoid Arthritis NA NA NA 1 drug 35839194 IEEE/ACM Trans Comput Biol Bioinform 2023
90 42.5 1935 LL Drug, Disease, Gene NA NA Biased random walks Drug Disease Association (DDA) NA Case studies Rheumatoid Arthritis NA NA NA 1 drug 35839194 IEEE/ACM Trans Comput Biol Bioinform 2023
90 42.5 1935 SLAMS Drug, Disease, Gene NA NA Biased random walks Drug Disease Association (DDA) NA Case studies Rheumatoid Arthritis NA NA NA 1 drug 35839194 IEEE/ACM Trans Comput Biol Bioinform 2023
90 42.5 1935 MalaCards (MC) Drug, Disease, Gene NA NA Biased random walks Drug Disease Association (DDA) NA Case studies Rheumatoid Arthritis NA NA NA 1 drug 35839194 IEEE/ACM Trans Comput Biol Bioinform 2023
91 40.5 142 NA Drug, Disease, Gene NA NA Matrix Factorization Drug Disease Association (DDA) NA NA NA NA NA NA NA 26078775 Comput Math Methods Med 2015
92 38.4 1444 CAS Biomedical Knowledge Graph(COVID-19) Disease, Gene, Pathway, Virus, Side-effect, Clinical Trial, Small molecule, Molecular Function NA NA A computer algorithm-driven drug-ranking method Drug Disease Association (DDA) NA Special studies COVID-19 NA NA NA Top 50 drugs 34297570 J Chem Inf Model 2021
93 37.65 896 FD dataset Drug Drug: drug perturbation gene expression level, structural fingerprint and physicochemical property DAMT-Model Convolutional Neural Network (CNN),Domain-adversarial learning,Bidirectional LSTM (Bi-LSTM) Drug Disease Association (DDA) https://github.com/JohnnyY8/DAMT-Model NA NA NA NA NA NA 31999334 Bioinformatics 2020
93 37.65 896 SMDC Drug Drug: drug perturbation gene expression level, structural fingerprint and physicochemical property DAMT-Model Convolutional Neural Network (CNN),Domain-adversarial learning,Bidirectional LSTM (Bi-LSTM) Drug Disease Association (DDA) https://github.com/JohnnyY8/DAMT-Model NA NA NA NA NA NA 31999334 Bioinformatics 2020
94 30.5 604 Yamanishi Drug, Disease, Target NA Heter-LP Label Propagation Drug Target Interaction (DTI),Drug Disease Association (DDA) NA NA NA NA NA NA NA 30547450 Methods Mol Biol 2019
95 27.6 1110 NA Drug, Disease, Gene, Pathway, Side-effect NA NA Support Vector Machine (SVM),Decision Tree (DT),Random Forest (RF) Drug Disease Association (DDA) NA NA NA NA NA NA NA 32674665 Health Informatics J 2020
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