| Recommendation |
ID |
Data Information |
Model Information |
Application Information |
Reference |
| Rank |
Total_Score |
Model_ID |
Dataset_Name |
Element_type |
Data_features |
Model_name |
Algorithm_name |
Prediction_type |
Code_source |
Study_types |
Disease_name |
Target_name |
Drug_name |
Interaction_type |
Recommended_Number |
PMID |
Journal |
Publication_Year |
| 1 |
80.3 |
1892 |
DrugBank |
Drug, Target |
Drug: chemical structure information, Target: target sequence |
PPAEDTI |
Deep Autoencoder |
Drug Target Interaction (DTI) |
https://github.com/LiYuechao1998/PPAEDTI |
Case studies |
NA |
hsa:779 (calcium voltage-gated channel subunit alpha1 S) |
NA |
NA |
Top 20 drugs |
36301791 |
IEEE J Biomed Health Inform |
2023 |
| 1 |
80.3 |
1892 |
DrugBank |
Drug, Target |
Drug: chemical structure information, Target: target sequence |
PPAEDTI |
Deep Autoencoder |
Drug Target Interaction (DTI) |
https://github.com/LiYuechao1998/PPAEDTI |
Case studies |
NA |
NA |
Nisoldipine |
NA |
Top 20 targets |
36301791 |
IEEE J Biomed Health Inform |
2023 |
| 1 |
80.3 |
1892 |
DrugBank |
Drug, Target |
Drug: chemical structure information, Target: target sequence |
PPAEDTI |
Deep Autoencoder |
Drug Target Interaction (DTI) |
https://github.com/LiYuechao1998/PPAEDTI |
Case studies |
NA |
hsa:775 (calcium voltage-gated channel subunit alpha1 C) |
NA |
NA |
Top 20 drugs |
36301791 |
IEEE J Biomed Health Inform |
2023 |
| 2 |
73.2 |
1981 |
DrugBank |
Drug, Target |
Drug: SMILES, Target: the amino acid sequences |
GIFDTI |
Convolutional Neural Network (CNN),Transformer |
Drug Target Interaction (DTI) |
https://github.com/zhaoqichang/GIFDTI |
Case studies |
NA |
NA |
Fludiazepam |
NA |
Top 20 targets |
36445997 |
IEEE/ACM Trans Comput Biol Bioinform |
2023 |
| 2 |
73.2 |
1981 |
DrugBank |
Drug, Target |
Drug: SMILES, Target: the amino acid sequences |
GIFDTI |
Convolutional Neural Network (CNN),Transformer |
Drug Target Interaction (DTI) |
https://github.com/zhaoqichang/GIFDTI |
Case studies |
NA |
Epidermal Growth Factor Receptor (EGFR) |
NA |
NA |
Top 20 drugs |
36445997 |
IEEE/ACM Trans Comput Biol Bioinform |
2023 |
| 3 |
72.6 |
1614 |
DrugBank |
Drug |
Drug: enzymes, side effects, substructures and targets |
GCNMK |
Graph Convolutional Network with multi-kernel (GCNMK) |
Drug Drug Interaction (DDI) |
NA |
Case studies |
Breast neoplasms |
NA |
NA |
NA |
Top 10 drugs |
34864856 |
Brief Bioinform |
2022 |
| 3 |
72.6 |
1614 |
DrugBank |
Drug |
Drug: enzymes, side effects, substructures and targets |
GCNMK |
Graph Convolutional Network with multi-kernel (GCNMK) |
Drug Drug Interaction (DDI) |
NA |
Case studies |
Colorectal neoplasms |
NA |
NA |
NA |
Top 10 drugs |
34864856 |
Brief Bioinform |
2022 |
| 3 |
72.6 |
1614 |
DrugBank |
Drug |
Drug: enzymes, side effects, substructures and targets |
GCNMK |
Graph Convolutional Network with multi-kernel (GCNMK) |
Drug Drug Interaction (DDI) |
NA |
Case studies |
Lung neoplasms |
NA |
NA |
NA |
Top 10 drugs |
34864856 |
Brief Bioinform |
2022 |
| 4 |
68.7 |
2091 |
DrugBank |
Drug, Gene |
NA |
DGCL (Dynamic hyperGraph Contrastive Learning) |
Graph Neural Network (GNN),Multi Layer Perception (MLP) |
Drug Gene Interaction (DGI) |
https://github.com/wentao228/DGCL |
Case studies |
NA |
HMOX1 |
NA |
NA |
Top 10 drugs |
37864294 |
Brief Bioinform |
2023 |
| 5 |
53 |
1748 |
DrugBank |
Drug, Target |
Drug: SMILES, Target: the amino acid sequences |
MHSADTI |
Graph Attention Network (GAT),Multi-head self-attention mechanism |
Drug Target Interaction (DTI) |
NA |
NA |
NA |
NA |
NA |
NA |
NA |
33956632 |
IEEE/ACM Trans Comput Biol Bioinform |
2022 |
| 6 |
51.85 |
1518 |
DrugBank |
Drug, Target |
Drug: SMILES, Target: the amino acid sequences |
DTI-End-to-End-DL |
Convolutional Neural Network (CNN) |
Drug Target Interaction (DTI) |
https://github.com/larngroup/DTI-End-to-End-DL |
NA |
NA |
NA |
NA |
NA |
NA |
32142454 |
IEEE/ACM Trans Comput Biol Bioinform |
2021 |
| 7 |
50.3 |
1787 |
DrugBank |
Drug, Target |
Drug: chemical structure, target: protein sequence |
Ro-DNILMF |
Integrated logistic matrix factorization |
Drug Target Interaction (DTI) |
https://github.com/LJX0326/Ro-DNILMF.git |
NA |
NA |
NA |
NA |
NA |
NA |
36014371 |
Molecules |
2022 |
| 8 |
42.5 |
1935 |
DrugBank |
Drug, Disease, Gene |
NA |
NA |
Biased random walks |
Drug Disease Association (DDA) |
NA |
Case studies |
Rheumatoid Arthritis |
NA |
NA |
NA |
1 drug |
35839194 |
IEEE/ACM Trans Comput Biol Bioinform |
2023 |