The search result for the key word "NA"

A total of 107 results found based on your keywords
Recommendation ID Data Information Model Information Application Information Reference
Rank Total_Score Model_ID Dataset_Name Element_type Data_features Model_name Algorithm_name Prediction_type Code_source Study_types Disease_name Target_name Drug_name Interaction_type Recommended_Number PMID Journal Publication_Year
1 91.9 2042 NA Drug, Disease, Target Drug: SMILES, Target: the amino acid sequences VGAEDTI Random Forest (RF),Variational Graph AutoEncoder (VGAE),Graph AutoEncoder (GAE) Drug Target Interaction (DTI) https://github.com/FengYinFei/VGAEDTI Case studies NA NA NA Drug target interaction Top 15 drugs 37415176 BMC Bioinformatics 2023
2 85.4 815 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Levodopa NA Top 5 diseases 31869322 PLoS Comput Biol 2019
2 85.4 815 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Doxorubicin NA Top 5 diseases 31869322 PLoS Comput Biol 2019
2 85.4 815 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH OMC Overlap Matrix Completion Drug Disease Association (DDA) https://github.com/BioinformaticsCSU/OMC Case studies NA NA Flecainide NA Top 5 diseases 31869322 PLoS Comput Biol 2019
3 84.3 1807 NA Drug, Disease Drug: SMILES, Disease: Mesh semantic GCMM (Graph convolution network based on a multimodal attention mechanism) Convolutional Neural Network (CNN) Drug Disease Association (DDA) https://github.com/FanZhang0820/GCMM Case studies Alzheimer's Disease (AD) NA NA NA Top 5 drugs 36100897 BMC Bioinformatics 2022
4 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Chloroquine NA Top 10 diseases 34850815 Brief Bioinform 2022
4 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Flurbiprofen NA Top 10 diseases 34850815 Brief Bioinform 2022
4 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Metoprolol NA Top 10 diseases 34850815 Brief Bioinform 2022
4 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Propranolol NA Top 10 diseases 34850815 Brief Bioinform 2022
4 83 1613 NA Drug, Disease Drug: Chemical substructures, the target domains and the gene ontology annotations of target target, Disease: MeSH CTST Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies NA NA Aripiprazole NA Top 10 diseases 34850815 Brief Bioinform 2022
5 82.7 1848 NA Drug, Disease, Target, Gene, Pathway Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies Breast neoplasms NA NA NA Top 10 drugs 36182762 Comput Biol Med 2022
5 82.7 1848 NA Drug, Disease, Target, Gene, Pathway Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies Brain neoplasms NA NA NA Top 10 drugs 36182762 Comput Biol Med 2022
5 82.7 1848 NA Drug, Disease, Target, Gene, Pathway Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies NA NA Dexamethasone NA Top 10 diseases 36182762 Comput Biol Med 2022
5 82.7 1848 NA Drug, Disease, Target, Gene, Pathway Drug: SMILES, Disease: MeSH REDDA (Relations-Enhanced Drug-Disease Association prediction) Heterogeneous Graph Convolutional Network (HGCN) Drug Disease Association (DDA) https://github.com/gu-yaowen/REDDA Case studies NA NA Ifosfamide NA Top 10 diseases 36182762 Comput Biol Med 2022
6 81 2099 NA Drug, Disease, Target, Side-effect Drug: SMILES, Target: the amino acid sequences MOVE Multi Layer Perception (MLP) Drug Target Interaction (DTI) https://github.com/scu-kdde/Bioinfo-MOVE2.0 Case studies COVID-19 Peroxisome proliferator-activated receptor gamma(P37231), Peroxisome proliferator-activated receptor alpha(Q07869), Apoptosis regulator Bcl-2(P10415), Angiotensin-converting enzyme 2(Q9BYF1), Cystic fibrosis transmembrane conductance regulator(P13569), Nuclear receptor subfamily 1 group I member 2(O75469), Annexin A1(P04083) NA NA Top 7 drugs 37586602 Methods 2023
7 80.5 393 NA Drug, Disease, Target , Side-effect Drug: chmical structure, Target: genome sequences DTINet Random Walk with Restart (RWR) Drug Target Interaction (DTI) https://github.com/luoyunan/DTINet Case studies NA COX proteins NA NA 3 drugs 28924171 Nat Commun 2017
8 78.3 1615 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH HINGRL Random Forest (RF) Drug Disease Association (DDA) https://github.com/stevejobws/HINGRL Case studies NA Clozapine NA NA Top 10 diseases 34891172 Brief Bioinform 2022
8 78.3 1615 NA Drug, Disease, Target Drug: SMILES, Disease: MeSH HINGRL Random Forest (RF) Drug Disease Association (DDA) https://github.com/stevejobws/HINGRL Case studies Breast neoplasms NA NA NA Top 10 drugs 34891172 Brief Bioinform 2022
9 77.875 509 NA Drug, Disease Drug: substructures, Disease: MeSH NTSIM (Network Topological Similarity-based Inference Method) Label Propagation Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 10 diseases 29879508 Methods 2018
10 77.3 957 NA Drug, Disease, Target NA BiFusion (Bipartite graph convolution network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/zcwang0702/BiFusion Case studies Parkinson’s Disease (PD) NA NA NA Top 10 drugs 32657387 Bioinformatics 2020
10 77.3 957 NA Drug, Disease, Target NA BiFusion (Bipartite graph convolution network) Graph Convolutional Network (GCN) Drug Disease Association (DDA) https://github.com/zcwang0702/BiFusion Case studies Breast carcinoma NA NA NA Top 5 drugs 32657387 Bioinformatics 2020
11 77.2 949 NA Drug, Disease, Target Drug: SMILES, Target: target sequence data in FASTA format Disease: MeSH TS-SVD Random Forest (RF) Drug Disease Association (DDA) NA Case studies Non-Small Cell Lung Cancer (NSCLC) NA NA NA Top 10 drugs 32340956 IEEE Trans Nanobioscience 2020
12 76.6 1691 NA Drug, Target Drug: SMILES, Target: amino-acid sequences NA Convolutional Neural Network (CNN),Deep Neural Network (DNN),Random Forest (RF) Drug Target Interaction (DTI) https://github.com/Shkev/Sars-CoV-2-NSP-Predictions Case studies NA NA NA Drug target interaction 13 predictions 35468672 Front Biosci (Landmark Ed) 2022
13 76.1 1487 NA Drug, Gene NA GraphRepur Graph Neural Network (GNN) Drug Disease Association (DDA) https://github.com/cckamy/GraphRepur Case studies Breast cancer NA NA NA Top 30 drugs 33739367 Bioinformatics 2021
13 76.1 298 NA Compound, Target Compound: SMILES, Target: Sequence REMAP Dual Regularized One-Class Collaborative Filtering Compound Protein Interaction (CPI) https://github.com/hansaimlim/REMAP Case studies Many types of cancer NA NA NA Top 7 drugs 27716836 PLoS Comput Biol 2016
14 76 1578 NA Drug, Target Drug: chemical structures, Target: primary sequence GANDTI Generative Adversarial Network (GAN),Graph convolutional autoencoder Drug Target Interaction (DTI) NA Case studies NA NA Olanzapine NA Top 10 targets 32750854 IEEE/ACM Trans Comput Biol Bioinform 2022
14 76 1578 NA Drug, Target Drug: chemical structures, Target: primary sequence GANDTI Generative Adversarial Network (GAN),Graph convolutional autoencoder Drug Target Interaction (DTI) NA Case studies NA NA Aripiprnazole NA Top 10 targets 32750854 IEEE/ACM Trans Comput Biol Bioinform 2022
14 76 1578 NA Drug, Target Drug: chemical structures, Target: primary sequence GANDTI Generative Adversarial Network (GAN),Graph convolutional autoencoder Drug Target Interaction (DTI) NA Case studies NA NA Ziprasidone NA Top 10 targets 32750854 IEEE/ACM Trans Comput Biol Bioinform 2022
14 76 1578 NA Drug, Target Drug: chemical structures, Target: primary sequence GANDTI Generative Adversarial Network (GAN),Graph convolutional autoencoder Drug Target Interaction (DTI) NA Case studies NA NA Quetiapine NA Top 10 targets 32750854 IEEE/ACM Trans Comput Biol Bioinform 2022
14 76 1578 NA Drug, Target Drug: chemical structures, Target: primary sequence GANDTI Generative Adversarial Network (GAN),Graph convolutional autoencoder Drug Target Interaction (DTI) NA Case studies NA NA Clozapine NA Top 10 targets 32750854 IEEE/ACM Trans Comput Biol Bioinform 2022
15 74.9 1623 NA Drug Drug: chemical structures, Target: protein sequence DOTA (Drug repositioning approach using Optimal Transport for Alzheimer's disease) Deep Autoencoder (Multi-modal,Wasserstein variational) Drug Disease Association (DDA) https://github.com/fawer/DOTA Special studies Alzheimer's Disease (AD) NA NA NA Top 20 drugs 35204697 Biomolecules 2022
16 74.3 694 NA Drug, Target Drug: Chemical structure, Target: target sequence LASSO Deep Neural Network (DNN) Drug Target Interaction (DTI) NA Case studies Breast Cancer NA NA NA Top 5 drugs 30939415 Comput Biol Chem 2019
17 73.7 1366 NA Drug, Target Molecular descriptors NA Random Forest (RF) Drug Disease Association (DDA) https://github.com/sblab/DTN Special studies Hyperlipidemia NA NA NA Top 9 drugs 34030115 Comput Biol Chem 2021
18 72.95 2134 NA Drug Drug: SMILES NA Graph Attention Network (GAT),Graph Isomorphism Network (GIN) Drug Target binding Affinity (DTA) NA Special studies COVID-19 SARS-CoV-2 main protease (Mpro) NA NA Top 10 drugs 37960886 J Chem Inf Model 2023
19 72.5 741 NA Drug, Target Drug: structure, Target: sequence NA Low Rank Embedding (LRE) Drug Target Interaction (DTI) NA Case studies NA NA NA Drug target interaction Top 30 predictions 28541222 IEEE/ACM Trans Comput Biol Bioinform 2019
19 72.5 764 NA Drug, Target Drug: structure, Target: sequence MCM Matrix Completion Drug Target Interaction (DTI) NA Case studies NA NA NA Drug target interaction Top 26 predictions 31538961 IET Syst Biol 2019
20 72.35 812 NA Drug, Disease, Target , Side-effect NA deepDR Multimodal deep autoencoder (MDA),Collective variational autoencoder (cVAE),Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/ChengF-Lab/deepDR Case studies Alzheimer's Disease (AD) NA NA NA Top 20 drugs 31116390 Bioinformatics 2019
20 72.35 812 NA Drug, Disease, Target , Side-effect NA deepDR Multimodal deep autoencoder (MDA),Collective variational autoencoder (cVAE),Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/ChengF-Lab/deepDR Case studies Parkinson’s Disease (PD) NA NA NA Top 20 drugs 31116390 Bioinformatics 2019
21 72.3 125 NA Drug, Disease Drug: structure chemical, target, side-effect; Diseases: disease phenotypes, disease ontology, disease genes DDR Block Coordinate Descent (BCD) Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 25954437 AMIA Annu Symp Proc 2014
21 72.3 125 NA Drug, Disease Drug: structure chemical, target, side-effect; Diseases: disease phenotypes, disease ontology, disease genes DDR Block Coordinate Descent (BCD) Drug Disease Association (DDA) NA Case studies Systemic Lupus Erythematosus (SLE) NA NA NA Top 10 drugs 25954437 AMIA Annu Symp Proc 2014
22 72.15 2125 NA Drug, Target, Pathway, Phenotype NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Rheumatoid arthritis NA NA NA Top 2 drugs 37925215 Artif Intell Med 2023
22 72.15 2125 NA Drug, Target, Pathway, Phenotype NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Left ventricular hypertrophy NA NA NA Top 1 drug 37925215 Artif Intell Med 2023
22 72.15 2125 NA Drug, Target, Pathway, Phenotype NA BEHOR Graph Neural Network (GNN) Drug Disease Association (DDA) https://zenodo.org/record/8402843 Case studies Congestive heart failure NA NA NA Top 2 drugs 37925215 Artif Intell Med 2023
23 72.1 1244 NA Drug, Disease Drug: chemical structural, CMLDR Collaborative metric learning algorithm Drug Disease Association (DDA) NA Case studies NA NA Risperidone NA Top 20 diseases 31283509 IEEE/ACM Trans Comput Biol Bioinform 2021
23 72.1 1244 NA Drug, Disease Drug: chemical structural, CMLDR Collaborative metric learning algorithm Drug Disease Association (DDA) NA Case studies NA NA Cyclophosphamide NA Top 20 diseases 31283509 IEEE/ACM Trans Comput Biol Bioinform 2021
24 71.75 424 NA Drug, Disease, Gene Drug: SMILES, Disease: MeSH SSGC (Semi-Supervised Graph Cut) Semi-supervised graph cut Drug Disease Association (DDA) NA Case studies Non-Small Cell Lung Cancer (NSCLC) NA NA NA Top 20 drugs 29297383 BMC Med Genomics 2017
24 71.75 424 NA Drug, Disease, Gene Drug: SMILES, Disease: MeSH SSGC (Semi-Supervised Graph Cut) Semi-supervised graph cut Drug Disease Association (DDA) NA Case studies Alcohol dependence NA NA NA Top 20 drugs 29297383 BMC Med Genomics 2017
24 71.75 424 NA Drug, Disease, Gene Drug: SMILES, Disease: MeSH SSGC (Semi-Supervised Graph Cut) Semi-supervised graph cut Drug Disease Association (DDA) NA Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 20 drugs 29297383 BMC Med Genomics 2017
24 71.75 424 NA Drug, Disease, Gene Drug: SMILES, Disease: MeSH SSGC (Semi-Supervised Graph Cut) Semi-supervised graph cut Drug Disease Association (DDA) NA Case studies Huntington Disease (HD) NA NA NA Top 20 drugs 29297383 BMC Med Genomics 2017
25 71.2 997 NA Drug Drug: structure, distance, target CATNIP XGBoost Drug Drug Interaction (DDI) https://github.com/coryandar/CATNIP Case studies Parkinson’s Disease (PD) NA NA NA 2 drugs 32764756 PLoS Comput Biol 2020
25 71.2 997 NA Drug Drug: structure, distance, target CATNIP XGBoost Drug Drug Interaction (DDI) https://github.com/coryandar/CATNIP Case studies Type 2 Diabetes Mellitus (T2DM) NA NA NA 1 drug 32764756 PLoS Comput Biol 2020
26 70.1 789 NA Drug, Disease Drug: SMILES, Diseases: MeSH terms NA Non-linear computational approach Drug Disease Association (DDA) http://bioinformatics.aut.ac.ir/drug-disc/ (Data) Case studies NA NA NA Drug disease interaction Top 16 predictions 31726977 BMC Bioinformatics 2019
27 69.4 1769 NA Drug, Target, Pathway NA MSDF-CNN Graph Convolutional Network (GCN) Drug Target Interaction (DTI) https://github.com/lemonfino/MSDF-CNN Special studies Parkinson’s Disease (PD) HTR2A NA NA Top 10 drugs 35897954 Molecules 2022
28 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Small Cell Lung Cancer (SCLC) NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
28 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Polysubstance abuse NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
28 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Huntington Disease (HD) NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
28 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Non-Small Cell Lung Cancer (NSCLC) NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
28 69.38 122 NA Drug, Disease, Target Drug: SMILES, Target: target sequence, Disease: MeSH terms TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) Heterogeneous Graph Based Inference (HGBI) Drug Disease Association (DDA) NA Case studies Alcohol dependence NA NA NA Top 10 drugs 24974205 Bioinformatics 2014
29 68.9 2098 NA Drug, Disease, Target, miRNA NA MTLDR (Multi-task learning framework for drug repurposing) Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies Tourette's Syndrome NA NA NA Top 10 drugs 37516260 Methods 2023
29 68.9 2098 NA Drug, Disease, Target, miRNA NA MTLDR (Multi-task learning framework for drug repurposing) Graph Convolutional Network (GCN) Drug Disease Association (DDA) NA Case studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 37516260 Methods 2023
30 68.5 1768 NA Drug, Disease, Target NA NTD-DR Nonnegative tensor decomposition Drug Disease Association (DDA) https://github.com/AliJam82/NTD-DR Case studies Breast ductal carcinoma, Prostate cancer, Pancreatic neoplasms, Colorectal neoplasms, Small cell lung carcinoma NA NA NA Top 50 drugs 35862409 PLoS One 2022
30 68.5 672 NA Gene, Celllines NA NA Deep neural Network (DNN),Support Vector Machine (SVM),Random Forest (RF),Gradient Boosted Machine with trees (GBM),logistic regression with elastic net regularization (EN) Drug Disease Association (DDA) NA Special studies Depressive Disorder NA NA NA Top 8 drugs 30010603 IEEE J Biomed Health Inform 2019
30 68.5 672 NA Gene, Celllines NA NA Deep neural Network (DNN),Support Vector Machine (SVM),Random Forest (RF),Gradient Boosted Machine with trees (GBM),logistic regression with elastic net regularization (EN) Drug Disease Association (DDA) NA Special studies Schizophrenia NA NA NA Top 8 drugs 30010603 IEEE J Biomed Health Inform 2019
31 68.2 192 NA Drug, Disease Disease: Phenotypic terms PhenoPredict The iterative network-based ranking algorithm Drug Disease Association (DDA) NA Special studies Schizophrenia NA NA NA Top 20 drugs 26151312 J Biomed Inform 2015
32 68.1 467 NA Drug, Target, Side-effect Drug: chemical properties, target targets, side-effect NA Pareto dominance,Collaborative filtering Drug Disease Association (DDA) NA NA NA NA NA Drug disease interaction Top 20 predictions 29649971 BMC Bioinformatics 2018
33 67.8 2015 NA Drug, Gene NA DTSEA (Drug Target Set Enrichment Analysis) Random Walk with Restart (RWR) Drug Disease Association (DDA) https://github.com/hanjunwei-lab/DTSEAData Special studies COVID-19 NA NA NA Top 10 drugs 37105108 Comput Biol Med 2023
34 67.3 1836 NA Drug, Target Drug: Fingerprint, KUALA (Kinase drUgs mAchine Learning frAmework) Naïve Bayes (NB),Logistic regression (LR),Support Vector Machine (SVM),Decision Tree (DT),Random Forest (RF),Neural Network (NNet),eXtreme Gradient Boosting (XGBoost),K-Nearest Neighbour (K-NN),Classification and Regression Tree (CART),Least Absolute Shrinkage and Selection Operator (LASSO),Ridge Regression (RIDGE),Elastic net regression (ELNET) Drug Target Interaction (DTI) https://github.com/molinfrimed/multi-kinases Case studies NA Kinases NA Drug target interaction 5 pedictions 36284125 Sci Rep 2022
35 67 1021 NA Drug, Disease, miRNA Drug: chemical structure, side-effect, functional consistency; miRNA: target genes, disease targets; Disease: MeSH BIMC Bilateral-inductive matrix completion (BIMC) Drug Disease Association (DDA) https://github.com/Deepthi-K523/BIMC Case studies NA NA Aminolevulinic acid NA Top 10 diseases 32583015 Mol Genet Genomics 2020
35 67 1021 NA Drug, Disease, miRNA Drug: chemical structure, side-effect, functional consistency; miRNA: target genes, disease targets; Disease: MeSH BIMC Bilateral-inductive matrix completion (BIMC) Drug Disease Association (DDA) https://github.com/Deepthi-K523/BIMC Case studies NA NA Almitrine NA Top 10 diseases 32583015 Mol Genet Genomics 2020
36 65.5 2087 NA Drug, Disease, Target, Side-effect Drug: SMILES, Target: the amino acid sequences BG-DTI Convolutional Neural Network (CNN),Graph Neural Network (GNN),Graph Attention Network (GAT),Support Vector Machine (SVM) Drug Target Interaction (DTI) https://github.com/wyx2012/BG-DTI NA NA NA NA NA NA 37764321 Molecules 2023
37 64.9 1306 NA Drug, Virus Drug: chemical structure, Virus: d2* dissimilarity/distance (at k=6) between the viral genome sequences DVA (Drug Virus Association) Matrix Completion Drug Virus Association (DVA) www.github.com/AanchalMongia/DVA Case studies COVID-19 SARS-CoV-2 NA NA Top 6 drugs 33907209 Sci Rep 2021
38 64.8 1814 NA Drug, chemical NA NA Knowledge Graph Embedding Drug Disease Association (DDA) NA Special studies Alzheimer's Disease (AD) NA NA NA Top 10 drugs 36180861 BMC Bioinformatics 2022
39 64.6 2116 NA Drug Drug: SMILES NA Graph Convolutional Network (GCN),XGBoost Drug Target Interaction (DTI) NA Special studies Parkinson’s Disease (PD) PINK1 (Phosphatase and Tensin homologue-induced kinase 1) NA NA Top 22 drugs 37544165 Comput Methods Programs Biomed 2023
40 63.7 1856 NA Drug, Disease, Target, Side-effect NA DTI-GTN Graph Transformer Network Drug Target Interaction (DTI) https://github.com/q498756498/DTI-GTN Case studies NA HTR1A NA NA Top 4 drugs 36329406 BMC Bioinformatics 2022
40 63.7 1856 NA Drug, Disease, Target, Side-effect NA DTI-GTN Graph Transformer Network Drug Target Interaction (DTI) https://github.com/q498756498/DTI-GTN Case studies NA CHRM3 NA NA Top 2 drugs 36329406 BMC Bioinformatics 2022
41 63.2 356 NA Drug, Disease, Target NA Heter-LP Heterogeneous label propagation Drug Target Interaction (DTI),Drug Disease Association (DDA) NA Case studies Osteoarthritis with mild chondrodysplasia NA NA NA 2 drugs 28300647 J Biomed Inform 2017
42 62.9 36 NA Drug, Disease, Target, Gene, Pathway NA CauseNet Computing transition weights Drug Disease Association (DDA) NA Case studies Crohn's disease (CD) NA NA NA Top 5 drugs 24564553 BMC Bioinformatics 2013
43 62.5 1072 NA Drug, Disease, Target, Pathway, Therapeutic classes NA NMTF (Non-negative Matrix Tri-Factorization) Matrix Factorization Drug Target Interaction (DTI) https://github.com/DEIB-GECO/NMTF-DrugRepositioning Case studies NA NA NA Drug disease interaction Top 5 predictions 32365039 IEEE J Biomed Health Inform 2020
44 61.8 1096 NA Drug, Target Drug: SMILES, Target: sequence DLDTI Representation learning,Convolutional Neural Network (CNN) Drug Target Interaction (DTI) https://github.com/CUMTzackGit/DLDTI Case studies Atherosclerosis NA Tetramethylpyrazine NA 288 targets 33187537 J Transl Med 2020
45 60.1 1867 NA Drug, Target Drug: SMILES, Disease: MeSH, Target: sequence MHADTI (Multiview heterogeneous information network embedding with Hierarchical Attention mechanisms to discover potential Drug–Target Interaction) Multi Layer Perception (MLP) Drug Target Interaction (DTI) https://github.com/pxystudy/MHADTI Case studies NA NA Pregabalin,Oxycodone,Sunitinib,Acetaminophen,Gefitinib NA NA 36242566 Brief Bioinform 2022
46 59.9 1060 NA Drug, Disease, Target, Gene NA RepCOOL Random Forest (RF) Drug Disease Association (DDA) NA Case studies Breast cancer stage II NA NA NA Top 4 drugs 33008415 J Transl Med 2020
47 59.7 1140 NA Chemical molecules, Gene, Gene expression profiles NA MNBDR (Module Network Ba​​sed Drug Repositioning）LINC1000,Cmap Random Walk Drug Disease Association (DDA) https://github.com/nbnbhwyy/MNBDR Case studies Breast cancer NA NA NA NA 33375395 Genes (Basel) 2020
48 58.9 1260 NA Subject, object, predicate NA LBD Knowledge Graph Completion Drug Disease Association (DDA) https://github.com/kilicogluh/lbd-covid Special studies COVID-19 NA NA NA 5 drugs 33571675 J Biomed Inform 2021
49 58.7 725 NA Drug, Disease, Target Drug: drug-target target NA CLASH (Complementary Linkage with Anchoring and Scoring),Graph-based Semi-Supervised Learning (SSL) Drug Drug Interaction (DDI) NA Case studies Vascular dementia NA NA NA Top 11 drug 31337333 BMC Bioinformatics 2019
50 58.5 1322 NA Drug, Gene NA NA Deep Autoencoder,XGBoost Drug Target Interaction (DTI) https://github.com/tsjshg/ai-drug-dev Special studies Alzheimer's Disease (AD) NA NA NA Top 20 drugs 33941241 Alzheimers Res Ther 2021
51 56.6 380 NA Drug, Gene Drug: UniProt ID, PD-MRW Random Walk Drug Gene Association (DGA) NA Case studies Hepatocellular Carcinoma NA NA NA Top 20 drugs 27076463 IEEE/ACM Trans Comput Biol Bioinform 2017
52 56.5 1546 NA Drug, Disease, Gene NA GCAN (GRU-Cooperation-Attention-Network) GRU-Cooperation-Attention-Network (GCAN),RNN,Biased random walk Drug Disease Association (DDA) NA Case studies type I Gaucher disease NA NA NA Top 2 drugs 34789254 BMC Med Inform Decis Mak 2021
53 55.5 816 NA Drug, Target Drug: chemical structure, Target: GO terms OCSVM (One-class Support Vector Machine) Support Vector Machine (SVM) Drug Target Interaction (DTI) Additional file 4 NA NA NA NA NA NA 31881829 BMC Bioinformatics 2019
54 55.4 1915 NA Drug, Gene NA NA Random Walk with Restart (RWR) Drug Disease Association (DDA) NA Special studies Non-Small Cell Lung Cancer (NSCLC) NA NA NA Top 11 drugs 36768566 Int J Mol Sci 2023
54 55.4 1915 NA Drug, Gene NA NA Random Walk with Restart (RWR) Drug Disease Association (DDA) NA Special studies Colorectal Cancer NA NA NA Top 9 drugs 36768566 Int J Mol Sci 2023
55 53.5 586 NA Drug, Disease Drug: PubChem fingerprints, Disease: MeSH DrPOCS (projection onto convex sets) Matrix Completion Drug Disease Association (DDA) NA NA NA NA NA NA NA 29993698 IEEE/ACM Trans Comput Biol Bioinform 2019
56 51.4 1056 NA Drug, Target Drug: chemical structure PIMD Similarity Network Fusion (SNF) Drug Drug Interaction (DDI) https://github.com/Sepstar/PIMD/ Case studies NA NA NA NA NA 33075523 Genomics Proteomics Bioinformatics 2020
57 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Dysmenorrhea NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
57 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Psoriasis NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
57 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Urticaria NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
57 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Osteoarthritis NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
57 50.5 794 NA Drug, Target Drug: SMILES, Proten: the amino acid sequence BANDIT Bayesian Drug Target Interaction (DTI) Select pieces of custom code can be made available upon request. NA NA NA NA NA NA 31745082 Nat Commun 2019
57 50.5 2000 NA Drug, Disease, Target Drug: SMILES, Target: the amino acid sequences DT2Vec+ XGBoost Drug Target Interaction (DTI) https://github.com/elmira-amiri/DT2VecPlus NA NA NA NA NA NA 37193964 BMC Bioinformatics 2023
57 50.5 569 NA Drug, Disease, Target NA NA Random Forest (RF),Neural network Drug Disease Association (DDA) NA Case studies Chronic lymphocytic leukemia NA NA NA Candidate drugs with the mean AUC>0.9 30463505 BMC Bioinformatics 2018
58 49.5 1203 NA Drug, Virus NA IRNMF (Indicator Regularized non-negative Matrix Factorization) Non-negative Matrix Factorization (NMF) Drug Virus Association (DVA) https://github.com/dukebai/IRNMF NA NA NA NA NA NA 33584672 Front Immunol 2021
59 47.5 1795 NA Drug, Disease, Target, Side-effect, Substructure NA MGATRx Graph Neural Network (GNN) Drug Disease Association (DDA) https://github.com/yellajaswanth/MGATRx NA NA NA NA NA NA 34014830 IEEE/ACM Trans Comput Biol Bioinform 2022
60 45 1220 NA Drug, Disease, Gene NA SAveRUNNER (Searching off-lAbel dRUg aNd NEtwoRk) Bi-Random walk-based algorithm Drug Disease Association (DDA) NA NA NA NA NA NA NA 33544720 PLoS Comput Biol 2021
61 42.4 465 NA Drug, Target, Gene, Side-effect Drug: Chemical structure, target, Gene, side-effect NA Growing Self Organizing Map (GSOM) Drug Drug Interaction (DDI) https://github.com/fathimanush786/two_tiered_clustrering_data NA NA NA NA NA NA 29642848 BMC Bioinformatics 2018
62 40.7 1307 NA Drug, Target Drug: 2-D structural representations, CSConv2d Convolutional Block Attention Module (CBAM) Drug Target Interaction (DTI) NA NA NA NA NA NA NA 33925310 Biomolecules 2021
63 40.5 142 NA Drug, Disease, Gene NA NA Matrix Factorization Drug Disease Association (DDA) NA NA NA NA NA NA NA 26078775 Comput Math Methods Med 2015
64 39.2 154 NA Drug Drug: chemical structure NA Markov Clustering Drug Drug Interaction (DDI) NA NA NA NA NA NA NA 24934184 Chem Biol Drug Des 2015
65 27.6 1110 NA Drug, Disease, Gene, Pathway, Side-effect NA NA Support Vector Machine (SVM),Decision Tree (DT),Random Forest (RF) Drug Disease Association (DDA) NA NA NA NA NA NA NA 32674665 Health Informatics J 2020
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