Data information
Dataset Name:	Please Select: Bdataset BindingDB BIOSNAP Cdataset Davis DNdataset DTINet Fdataset Gdataset Gottlieb dataset Hetero HGBI KIBA Ldataset LRSSL Luo's dataset MATADOR NeoDTI OpenBioLink RepoDB Yamanishi Other	Data Source:	Please Select: ChEMBL ClinicalTrials.gov CMap Comparative Toxicogenomics Database (CTD) DisGeNET DrugBank DrugCentral GEO HPRD KEGG Matador MeSH OMIM Pathway Commons PDB PubChem SIDER STRING TCGA Therapeutics Data Commons (TDC) TTD Unified Medical Language System (UMLS) Uniprot Other
Data Type:	Please Select: Tabular Graph Other	Element type:	Please Select: Anatomies Atc Celllines Cellular Component Chemical Chemical molecules Clinical Trial Compound Disease Drug Gene Gene expression profiles miRNA Pathway Side-effect Substructure Symptom Target Therapeutic classes Other
Model information
Model name:	Please Select: AdaDR (Adaptive Graph Convolutional Networks for Drug Repositioning) Affinity2Vec ANMF ANTENNA Anti-Biofilm Anti-Dengue AOPEDF (Arbitrary-Order Proximity Embedded Deep Forest) AttentionSiteDTI BANDIT BEHOR BG-DTI BGMSDDA BiFusion (Bipartite graph convolution network) BIMC BindingSite-AugmentedDTA BNNR (Bounded Nuclear Norm Regularization) BRDTI CATNIP CauseNet CBPred CMLDR CSConv2d CTST DAMT-Model DDAGDL DDAPRED DDIPred DDR DDTE DEDTI-IEDTI deepDR DeepFusion DeepLPI DGCL (Dynamic hyperGraph Contrastive Learning) DGDTA DisDrugPred DLDTI DNDTI DOTA (Drug repositioning approach using Optimal Transport for Alzheimer's disease) DR2DI DRAGNN DRDA DRDSA (Drug Repositioning Deep Sparse Autoencoder) DREAMwalk DRHGCN (Drug Repositioning based on the Heterogeneous information fusion Graph Convolutional Network) DRIMC (Drug repositioning approach by using Bayesian inductive matrix completion) DRONet DrPOCS (projection onto convex sets) DRRS (Drug Repositioning Recommendation System) DrugRep-HeSiaGraph DrugRep-KG DRWBNCF DT2Vec DT2Vec+ DTI-End-to-End-DL DTI-GTN DTI-HeNE (DTI based on Heterogeneous Network Embedding) DTI-HETA DTI-MLCD DTINet DTIP_MDHN dtipred DTI-SNNFRA DTSEA (Drug Target Set Enrichment Analysis) DVA (Drug Virus Association) EMPHCN (Enhanced Message Passing and Hypergraph Convolutional Networks) GANDTI GCAN (GRU-Cooperation-Attention-Network) GCMM (Graph convolution network based on a multimodal attention mechanism) GCNMK GDRnet GEFA (Graph Early Fusion Affinity) geNnius (Graph Embedding Neural Network Interaction Uncovering System) GIFDTI GIPAE (Gaussian interaction profile kernel and autoencoder) GLGMPNN GraphDTA GraphPK (Graph-based Prior Knowledge) GraphRepur HAMN (Hybrid Attentional Memory Network) Heter-LP HINGRL HMLKGAT HNet-DNN ICAN (Interpretable Cross-Attention Network) IDDI-DNN iDrug IMCHGAN (Inductive Matrix Completion with Heterogeneous Graph Attention Network) IntegratedSim IRNMF (Indicator Regularized non-negative Matrix Factorization) KGE_NFM KUALA (Kinase drUgs mAchine Learning frAmework) LASSO LBD LMFDA LRSSL (Laplacian regularized sparse subspace learning) LUNAR MBiRW MccDTI MCM MdDTI MDTips MGATRx MHADTI MHGNN MHSADTI MLAN MLMC MNBDR MOVE MPTN MSBMF MSDF-CNN MSGNN-DTA MTLDR (Multi-task learning framework for drug repurposing) MULGA (Multi-view Learning and Graph Autoencoder framework) MultiDTI (Multi-modal DTI) NEDD NEDNBI NeoDTI (NEural integration of neighbOr information for DTI prediction) NerLTR-DTA NetPro NMFDR (Neural Metric Factorization model for computational Drug Repositioning) NMF-DR (Non-negative Matrix Factorization Drug Repurposing) NMTF (Non-negative Matrix Tri-Factorization) NTD-DR NTSIM (Network Topological Similarity-based Inference Method) OCSVM (One-class Support Vector Machine) OMC PD-MRW PhenoPredict PIMD PPAEDTI PREDICT (PREdicting Drug IndiCaTions) PreDR (Predict Drug Repositioning) PSGCN (Partner-specific drug repositioning approach based on graph convolutional network) PUDTI PUON RBM model REDDA (Relations-Enhanced Drug-Disease Association prediction) REMAP RepCOOL RLSDR (Regularized Least Square for Drug Repositioning) Ro-DNILMF RWHNDR (Random Walk on a Heterogeneous Network for Drug Repositioning) SATS SAveRUNNER (Searching off-lAbel dRUg aNd NEtwoRk) SDTNBI (Substructure–drug–target network-based inference) SHGCL-DTI SiSGC (Simplifying Graph Convolution) SKCNN SNF-NN (Similarity network fusion and neural networks) SPLCMF (Self-paced learning with collaborative matrix factorization) SPLNMTF (Self-Paced Non-negative Matrix Tri-Factorization) springD²A SSGC (Semi-Supervised Graph Cut) SSLDR TeM-DTBA (Time-efficient Multimodal Drug Target Binding Affinity) TL_HGBI (Triple Layer Heterogeneous Graph Based Inference) TNA-DR (Tail-Node Augmentation for Drug Repositioning) TP-NRWRH TransRGNN TransVAE-DTA (Transformer and Variational Autoencoder network for Drug-Target binding Affinity) TS-SVD VGAEDTI WES WMAGT Other	Evaluation method:	Please Select: 10-fold cross validation 3-fold cross validation 5-fold cross validation Few-shot link prediction evaluation Holdout k-fold cross validation Leave-One-Out cross validation Multiple resampling-based Nested cross validation Stratified cross validation Time slicing approach Other
Algorithm type:	Please Select: Classical Machine Learning Deep Learning Network-based propagation Recommendation system	Evaluation metrics:	Please Select: Accuracy (Ac) (ACC) Area Under Curve (AUC) (AUC-PR) (PR-AUC) (AUPR) (AUROC) (AUC-ROC) Balanced Accuracy (Ba) Brier Score (BS) Concordance Index (CI) F1-measure (F1) Hits Matthews Correlation Coefficient (MCC) Mean Rank (MR) Mean Reciprocal Rank (MRR) Mean Square Error (MSE) Negative Predictive Value (NPV) Pearson Correlation Coefficient (PCC) Positive Predictive Value (PPV) Precision (Pr) Recall (Re) Receiver Operation Characteristic (ROC) Regression toward the mean (r²m) Regression toward the Mean index (rm²) Root Mean Square Error (RMSE) Sensitivity (Sen) Specificity (Sp) (Spe) Standardized Mutual Information (SMI) The absolute value of relative error (ARE) The mean absolute error (MAE) The square determination coefficient (R²) Other
Algorithm name:	Please Select: Bayesian Bidirectional Long Short-Term Memory (Bi-LSTM) CatBoost Collaborative Filtering Collaborative metric learning algorithm Collective variational autoencoder (cVAE) Convolutional Neural Network (CNN) Decision Tree (DT) Deep Autoencoder Deep Forest Classifier Deep Neural Network (DNN) Deep sparse autoencoder Elastic net regression (ELNET) Extra tree classifier (ETC) eXtreme Gradient Boosting (XGBoost) Gated Fusion Mechanism Generative Adversarial Network (GAN) Geometric Deep Learning (GDL) Graph Attention Network (GAT) Graph Autoencoder (GAE) Graph convolutional autoencoder Graph Convolutional Network (GCN) Graph Embedding Algorithm Graph Isomorphism Network (GIN) Graph Neural Network (GNN) Graph Transformer Network Heterogeneous label propagation K-Nearest Neighbour (K-NN) Knowledge Graph Completion Knowledge Graph Embedding Label Propagation Logistic regression (LR) Markov Clustering Matrix Completion Matrix Factorization Message Passing Neural Network (MPNN) Multi-head self-attention mechanism Multilayer Perceptron Naïve Bayes (NB) Network embedding (NE) Neural Factorization Machine (NFM) Neural Network (NNet) Random Forest (RF) Random Walk Regularized Kernel Classifier Regularized Least Square Restricted Boltzmann Machine Ridge Regression (RIDGE) RNN Siamese Neural Network (SNN) Similarity Network Fusion (SNF) Singular Value Thresholding (SVT) Support Vector Machine (SVM) Transformer Other	Optimizer:	Please Select: Adam ADMM Other
Prediction type:	Please Select: Compound Protein Interaction (CPI) Drug Disease Association (DDA) Drug Disease Target associations Drug Drug Interaction (DDI) Drug Gene Association (DGA) Drug Gene Interaction (DGI) Drug Target binding Affinity (DTA) Drug Target Interaction (DTI) Drug Virus Association (DVA) Other	Ablation:	Please Select: Yes Other
Task type:	Please Select: Classification Clustering Ranking Regression Other	Code permission:	Please Select: 403 Forbidden 404 Page not found No code With code Disease Gene miRNA Pathway Target Side-effect Target Other
Application information
Disease study types:	Please Select: Case studies Special studies Other	Disease type:	Please Select: Autoimmune Diseases Bacterial infection Brain Diseases, Metabolic, Inborn Cancer Cardiovascular Diseases Central Nervous System Diseases Cerebrovascular Disorders Digestive System Diseases Infectious Diseases Joint Diseases Mental Disorder Metabolic Diseases Musculoskeletal Diseases Neurovascular Disease Nurodegenerative Diseases Nutrition Disorders Pain Respiratory Diseases Respiratory Tract Diseases Skin Diseases Substance-Related Disorders Virus Diseases Other
Target name:	Please Select: 3C-like protease 5-hydroxytryptamine receptors Accessory Sec system protein translocase subunit SecY2 ACE2 ADRA1B Adrenergic receptor Angiotensin-converting enzyme 2 Annexin A1 Apoptosis regulator Bcl-2 Calcium voltage-gated channel subunit alpha CHRM Clozapine COX proteins Cystic fibrosis transmembrane conductance regulator Dopamine receptor Dipeptidyl Peptidase 4 (DPP-4) DNA topoisomerase 2-alpha DNA-directed RNA polymerase subunit Elongation factor G Epidermal Growth Factor Receptor (EGFR) GABRA4 G-protein-coupled receptors (GPCRs) Helicase HMOX1 HTR Kinases Nterleukin-l beta Nuclear receptor subfamily 1 group I member 2 OPRD1 Peroxisome proliferator-activated receptor PINK1 (Phosphatase and Tensin homologue-induced kinase 1) Potassium voltage-gated channel subfamily H member 2 Receptor Tyrosine Kinases (RTKs) Ribosomal protein RNA-dependent RNA polymerase (RdRp) SARS-CoV-2 SLC6A4 Spike glycoprotein Tumor necrosis factor Other/option>	Disease name:	Please Select: Alcohol dependence Alzheimer's Disease (AD) Antimicrobial resistance Asthma Atherosclerosis Atopic Eczema Brain neoplasms (Carcinoma/Cancer) Breast Cancer (Carcinoma/Neoplasms) Breast ductal carcinoma Chronic lymphocytic leukemia Colorectal Cancer (Carcinoma/Neoplasms) Congestive heart failure Contact Dermatitis COVID-19 Crohn's disease (CD) Dengue Depressive Disorder Diabetes Dysmenorrhea Hepatocellular Carcinoma (Cancer/Neoplasms) Huntington Disease (HD) Hyperlipidemia Ischemic stroke Left ventricular hypertrophy Lung cancer (Carcinoma/Neoplasms) Methicillin-resistant Staphylococcus aureus Migrane Non-papillary renal cell cancer (Carcinoma/Neoplasms) Non-Small Cell Lung Cancer (NSCLC) (Carcinoma/Neoplasms) Obesity Osteoarthritis Pancreatic neoplasms (Carcinoma/Neoplasms) Parkinson's Disease (PD) Polysubstance abuse Prostate cancer (Carcinoma/Neoplasms) Psoriasis Rheumatoid Arthritis Schizophrenia Small Cell Lung Cancer (SCLC) (Carcinoma/Neoplasms) Substance abuse disorder Systemic Lupus Erythematosus (SLE) Tourette's Syndrome Type 2 Diabetes Mellitus (T2DM) Type I Gaucher disease Urticaria Vascular dementia Other
Interaction type:	Please Select: Drug disease interactio Drug target interaction Other	Drug name:	Please Select: Acetaminophen Almitrine Amantadine Aminolevulinic acid Amitriptyline Ampicillin Aripiprazole Asenapine Aspirin Astemizole Cabergoline Cefotaxime Ceftriaxone Chloroquine Ciprofloxacin Citalopram Clonidine Clozapine Cortisol Cyclophosphamide Dexamethasone Dextromethorphan Diltiazem Doxorubicin Enalapril Ephedrine Etoposide Felodipine Fenoldopam Fenoprofen Flecainide Fluconazole Flurazepam Flurbiprofen Frovatriptan Gabapentin Gefitinib Gemcitabine Ifosfamide Imatinib Indomethacin Irinotecan Leucovorin Levodopa Levofloxacin Loteprednol Melphalan Methotrexate Metoprolol Nimodipine Nisoldipine NSAIDs Ofloxacin Olanzapine Oxycodone Paclitaxel Podophyllotoxin Prednisolone Pregabalin Progesterone Propranolol Quetiapine Risperidone Salicylic acid Sparfloxacin Sunitinib Tacrolimus Tamoxifen Testosterone Tetramethylpyrazine Thiopental Tolmetin Triamcinolone Vincristine Warfarin Yohimbine Ziprasidone Zoledronic acid Other