| Recommendation |
ID |
Data Information |
Model Information |
Application Information |
Reference |
| Rank |
Total_Score |
Model_ID |
Dataset_Name |
Element_type |
Data_features |
Model_name |
Algorithm_name |
Prediction_type |
Code_source |
Study_types |
Disease_name |
Target_name |
Drug_name |
Interaction_type |
Recommended_Number |
PMID |
Journal |
Publication_Year |
| 1 |
82.1 |
1842 |
Gdataset |
Drug, Disease |
Drug: SMILES, Disease: MeSH |
PSGCN (Partner-specific drug repositioning approach based on graph convolutional network) |
Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) |
Drug Disease Association (DDA) |
https://github.com/xinliangSun/PSGCN |
Case studies |
Breast Cancer |
NA |
NA |
NA |
Top 10 drugs |
35921345 |
IEEE J Biomed Health Inform |
2022 |
| 1 |
82.1 |
1842 |
Cdataset |
Drug, Disease |
Drug: SMILES, Disease: MeSH |
PSGCN (Partner-specific drug repositioning approach based on graph convolutional network) |
Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) |
Drug Disease Association (DDA) |
https://github.com/xinliangSun/PSGCN |
Case studies |
Breast Cancer |
NA |
NA |
NA |
Top 10 drugs |
35921345 |
IEEE J Biomed Health Inform |
2022 |
| 1 |
82.1 |
1842 |
LRSSL |
Drug, Disease |
Drug: SMILES, Disease: MeSH |
PSGCN (Partner-specific drug repositioning approach based on graph convolutional network) |
Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) |
Drug Disease Association (DDA) |
https://github.com/xinliangSun/PSGCN |
Case studies |
Breast Cancer |
NA |
NA |
NA |
Top 10 drugs |
35921345 |
IEEE J Biomed Health Inform |
2022 |
| 2 |
80.4 |
1670 |
Fdataset |
Drug, Disease |
Drug: SMILES, Disease: MeSH |
DRWBNCF |
Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) |
Drug Disease Association (DDA) |
https://github.com/luckymengmeng/DRWBNCF |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
35039838 |
Brief Bioinform |
2022 |
| 2 |
80.4 |
1670 |
Cdataset |
Drug, Disease |
Drug: SMILES, Disease: MeSH |
DRWBNCF |
Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) |
Drug Disease Association (DDA) |
https://github.com/luckymengmeng/DRWBNCF |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
35039838 |
Brief Bioinform |
2022 |
| 2 |
80.4 |
1670 |
LRSSL |
Drug, Disease |
Drug: SMILES, Disease: MeSH |
DRWBNCF |
Graph Convolutional Network (GCN),Multi Layer Perceptron (MLP) |
Drug Disease Association (DDA) |
https://github.com/luckymengmeng/DRWBNCF |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
35039838 |
Brief Bioinform |
2022 |
| 3 |
78 |
1644 |
Cdataset |
Drug, Disease |
Drug: Chemical structure, Disease: MeSH |
NMF-DR (Non-negative Matrix Factorization Drug Repurposing) |
Non-negative Matrix Factorization (NMF) |
Drug Disease Association (DDA) |
https://github.com/sshaghayeghs/NMF-DR |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 5 drugs |
34875000 |
Bioinformatics |
2022 |
| 3 |
78 |
1644 |
Fdataset |
Drug, Disease |
Drug: Chemical structure, Disease: MeSH |
NMF-DR (Non-negative Matrix Factorization Drug Repurposing) |
Non-negative Matrix Factorization (NMF) |
Drug Disease Association (DDA) |
https://github.com/sshaghayeghs/NMF-DR |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 5 drugs |
34875000 |
Bioinformatics |
2022 |
| 3 |
78 |
1644 |
TL-HBGI |
Drug, Disease |
Drug: Chemical structure, Disease: MeSH |
NMF-DR (Non-negative Matrix Factorization Drug Repurposing) |
Non-negative Matrix Factorization (NMF) |
Drug Disease Association (DDA) |
https://github.com/sshaghayeghs/NMF-DR |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 5 drugs |
34875000 |
Bioinformatics |
2022 |
| 3 |
78 |
1644 |
DrugNet |
Drug, Disease |
Drug: Chemical structure, Disease: MeSH |
NMF-DR (Non-negative Matrix Factorization Drug Repurposing) |
Non-negative Matrix Factorization (NMF) |
Drug Disease Association (DDA) |
https://github.com/sshaghayeghs/NMF-DR |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 5 drugs |
34875000 |
Bioinformatics |
2022 |
| 4 |
77.7 |
2133 |
Fdataset |
Drug, Disease |
NA |
DRAGNN |
Multi Layer Perception (MLP) |
Drug Disease Association (DDA) |
https://github.com/1yiw/DRAGNN |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
38019732 |
Brief Bioinform |
2023 |
| 4 |
77.7 |
2133 |
Cdataset |
Drug, Disease |
NA |
DRAGNN |
Multi Layer Perception (MLP) |
Drug Disease Association (DDA) |
https://github.com/1yiw/DRAGNN |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
38019732 |
Brief Bioinform |
2023 |
| 4 |
77.7 |
2133 |
LRSSL |
Drug, Disease |
NA |
DRAGNN |
Multi Layer Perception (MLP) |
Drug Disease Association (DDA) |
https://github.com/1yiw/DRAGNN |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
38019732 |
Brief Bioinform |
2023 |
| 5 |
76.1 |
1487 |
NA |
Drug, Gene |
NA |
GraphRepur |
Graph Neural Network (GNN) |
Drug Disease Association (DDA) |
https://github.com/cckamy/GraphRepur |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 30 drugs |
33739367 |
Bioinformatics |
2021 |
| 6 |
74.3 |
694 |
NA |
Drug, Target |
Drug: Chemical structure, Target: target sequence |
LASSO |
Deep Neural Network (DNN) |
Drug Target Interaction (DTI) |
NA |
Case studies |
Breast Cancer |
NA |
NA |
NA |
Top 5 drugs |
30939415 |
Comput Biol Chem |
2019 |
| 7 |
72.1 |
2022 |
KEGG |
Drug, Disease, Gene, Pathway |
Drug: ATC, Disease: MeSH |
DREAMwalk |
Multi-layer random walk |
Drug Disease Association (DDA) |
https://github.com/eugenebang/DREAMwalk |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
37322032 |
Nat Commun |
2023 |
| 7 |
72.1 |
2022 |
Multi-scale interactome (MSI) network |
Drug, Disease, Gene |
Drug: ATC, Disease: MeSH |
DREAMwalk |
Multi-layer random walk |
Drug Disease Association (DDA) |
https://github.com/eugenebang/DREAMwalk |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
37322032 |
Nat Commun |
2023 |
| 7 |
72.1 |
2022 |
HetioNet |
Drug, Disease, Gene, Pathway |
Drug: ATC, Disease: MeSH |
DREAMwalk |
Multi-layer random walk |
Drug Disease Association (DDA) |
https://github.com/eugenebang/DREAMwalk |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
37322032 |
Nat Commun |
2023 |
| 8 |
71.7 |
771 |
Fdataset |
Drug, Disease |
Drug: SMILES, Proten: the amino acid sequence, Diseases: MeSH terms |
RWHNDR (Random Walk on a Heterogeneous Network for Drug Repositioning) |
Random Walk |
Drug Disease Association (DDA) |
NA |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 5 drugs |
29994051 |
IEEE/ACM Trans Comput Biol Bioinform |
2019 |
| 9 |
70.4 |
1866 |
Cdataset |
Drug, Disease, Target |
Drug: SMILES, Disease: MeSH, Target: sequence |
DDAGDL |
Geometric Deep Learning (GDL),XGBoost |
Drug Disease Association (DDA) |
https://github.com/stevejobws/DDAGDL |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
36125202 |
Brief Bioinform |
2022 |
| 9 |
70.4 |
1866 |
Fdataset |
Drug, Disease, Target |
Drug: SMILES, Disease: MeSH, Target: sequence |
DDAGDL |
Geometric Deep Learning (GDL),XGBoost |
Drug Disease Association (DDA) |
https://github.com/stevejobws/DDAGDL |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
36125202 |
Brief Bioinform |
2022 |
| 9 |
70.4 |
1866 |
Bdataset |
Drug, Disease, Target |
Drug: SMILES, Disease: MeSH, Target: sequence |
DDAGDL |
Geometric Deep Learning (GDL),XGBoost |
Drug Disease Association (DDA) |
https://github.com/stevejobws/DDAGDL |
Case studies |
Breast cancer |
NA |
NA |
NA |
Top 10 drugs |
36125202 |
Brief Bioinform |
2022 |
| 10 |
59.7 |
1140 |
NA |
Chemical molecules, Gene, Gene expression profiles |
NA |
MNBDR (Module Network Based Drug Repositioning)LINC1000,Cmap |
Random Walk |
Drug Disease Association (DDA) |
https://github.com/nbnbhwyy/MNBDR |
Case studies |
Breast cancer |
NA |
NA |
NA |
NA |
33375395 |
Genes (Basel) |
2020 |
| 10 |
59.7 |
1140 |
Golden standard |
Drug, Disease |
NA |
MNBDR (Module Network Based Drug Repositioning)LINC1000,Cmap |
Random Walk |
Drug Disease Association (DDA) |
https://github.com/nbnbhwyy/MNBDR |
Case studies |
Breast cancer |
NA |
NA |
NA |
NA |
33375395 |
Genes (Basel) |
2020 |