The PRNP gene homepage

General information
Gene symbol PRNP
Gene name prion protein
Chromosome 20
Chromosomal band p13
Imprinted Unknown
Genomic reference NG_009087.1
Transcript reference NM_000311.3
Associated with diseases AD, CJD, DLB, FFI, FTLD, GSS, HSAN, KURU, PD
Citation reference(s) -
Curators (1) Y Yang
Total number of public variants reported 120
Unique public DNA variants reported 43
Individuals with public variants 119
Hidden variants -
Date created December 16, 2014
Date last updated November 18, 2017
Version PRNP:171118

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
HGNC 9449
Entrez Gene 5621
PubMed articles PRNP
OMIM - Gene 176640
OMIM - Diseases AD (Alzheimer Disease)
CJD (Creutzfeldt-Jakob disease)
DLB (Lewy Body Dementia)
FFI (Fatal Familial Insomnia)
FTLD (Frontotemporal Lobar Degeneration)
GSS (Gerstmann-Straussler-Scheinker Disease)
HSAN (Hereditary Sensory and Autonomic Neuropathy)
KURU (Kuru)
PD (Parkinson Disease)
HGMD PRNP
GeneCards PRNP
GeneTests PRNP


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00000040 20 transcript variant 1 NM_000311.3 NP_000302.1 120


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