| Factor Information | |
|---|---|
| Data ID | 117 |
| Factor | the growth rate of the Heschl’s gyrus |
| Description | An explorative, whole-brain, thresholdfree cluster enhancement analysis revealed strong correlation between the growth rate of the Heschl’s gyrus, anterior planum temporale and language score at 12 months of age, corrected for demographic variables. |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | language score |
| p Value | 0.018 |
| Conclusion | Our longitudinal cohort study provides evidence for the early importance of left-dominant perisylvian regions in auditory and language development before direct postnatal exposure to native language. In congenital heart disease patients, the perioperative period results in a critical variability of brain growth rate in this region, which is a reliable neural correlate of language development at 1 year of age. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 415 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | D-TGA/IAA/CoA/TAAH/U-AVSD/VSD/PA, VSD |
| Reference | |
|---|---|
| PMID | 30957841 |
| Year | 2019 |
| Title | Left temporal plane growth predicts language development in newborns with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | newborns | |
| Source | cerebrum | |
| Region | Zurich, Switzerland | |
| Method | pre- and postoperative cerebral MRI | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | corrective or palliative cardiovascular bypass surgery; dextro-transposition of the great arteries (n = 33) planned for biventricular repair, and non-transposition of the great arteries pathologies consisting of a single ventricle undergoing staged palliation until Fontan procedure (n = 5) | |
| Group | N/A(Treatment) | N/A(Control) |
| Number | 44 | N/A |
| Age | 12 months | N/A |
| Gender (Male: Female) | 34:10 | N/A |
| Marker Level | N/A | N/A |
