| Factor Information | |
|---|---|
| Data ID | 120 |
| Factor | LCS at 12 months of age |
| Description | Whole-brain explorative analysis revealed that the brain growth rate of the left posterior perisylvian region was significantly positively correlated with the LCS at 12 months of age with no other clusters of correlation surviving the statistical significance threshold. |
| Biomarker | NA |
| Classification | F6 (psychosocial factor - other) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | brain growth rate of the left posterior perisylvian region |
| p Value | 0.0094 |
| Conclusion | Early importance of left-dominant perisylvian regions in language development before the lasting exposure to native language. Interindividual variability of regional brain growth rates in this area was found to be linked to variability in language performance at 12 months of age. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 415 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | D-TGA/IAA/CoA/TAAH/U-AVSD/VSD/PA, VSD |
| Reference | |
|---|---|
| PMID | 30957841 |
| Year | 2019 |
| Title | Left temporal plane growth predicts language development in newborns with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | newborns | |
| Source | cerebrum | |
| Region | Zurich, Switzerland | |
| Method | pre- and postoperative cerebral MRI | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | corrective or palliative cardiovascular bypass surgery; dextro-transposition of the great arteries (n = 33) planned for biventricular repair, and non-transposition of the great arteries pathologies consisting of a single ventricle undergoing staged palliation until Fontan procedure (n = 5) | |
| Group | a circumscribed region in one cluster(Treatment) | N/A(Control) |
| Number | 44 | N/A |
| Age | 12 months | N/A |
| Gender (Male: Female) | 34:10 | N/A |
| Marker Level | 1597 voxels (1.013 cm3) | N/A |
