| Factor Information | |
|---|---|
| Data ID | 1260 |
| Factor | preoperative digoxin exposure |
| Description | In multivariate analysis, preoperative digoxin exposure (OR 2.4 95%CI 1.3-4.4) was independently associated with postoperative Complete heart block (CHB) |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | postoperative CHB |
| p Value | <0.01 |
| OR | 2.4 |
| Conclusion | Preoperative factors, including a missense polymorphism in GJA5, are independently associated with increased risk for CHB. JA and intermittent conduction may prove useful in predicting recovery of AV conduction among patients with CHB following congenital heart surgery. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 509 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF/VSD/HLHS/ASD/CAVC |
| Reference | |
|---|---|
| PMID | 27826129 |
| Year | 2016 |
| Title | Genotypic and phenotypic predictors of complete heart block and recovery of conduction after surgical repair of congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Infants | |
| Source | N/A | |
| Region | Vanderbilt, USA | |
| Method | Daily rhythm assessment | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | congenital heart surgery, pacemaker (PM) implantation | |
| Group | 3rd degree block(Treatment) | No 3rd degree block(Control) |
| Number | 19(taotal:56) | 161(total:1143) |
| Age | 4 (1, 8.3) months | 6.1 (1.0, 46) months |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 19 (34%) | 161 (14%) |
