| Factor Information | |
|---|---|
| Data ID | 1264 |
| Factor | Junctional acceleration (JA) |
| Description | Junctional acceleration (JA) (OR 4.0 95%CI 1.1-15.1) and intermittent conduction noted during complete AV block (OR 9.1, 95%CI 1.0-80) were independently associated with 1:1 AV conduction recovery |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | 1:1 AV conduction recovery following incidence of postoperative 3rd degree AV block. |
| p Value | <0.05 |
| OR | 4 |
| Conclusion | Preoperative factors, including a missense polymorphism in GJA5, are independently associated with increased risk for CHB. JA and intermittent conduction may prove useful in predicting recovery of AV conduction among patients with CHB following congenital heart surgery. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 509 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF/VSD/HLHS/ASD/CAVC |
| Reference | |
|---|---|
| PMID | 27826129 |
| Year | 2016 |
| Title | Genotypic and phenotypic predictors of complete heart block and recovery of conduction after surgical repair of congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Infants | |
| Source | N/A | |
| Region | Vanderbilt, USA | |
| Method | Daily rhythm assessment | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | congenital heart surgery, pacemaker (PM) implantation | |
| Group | conduction recovery following incidence of postoperative 3rd degree AV block(Treatment) | no recovery following incidence of postoperative 3rd degree AV block(Control) |
| Number | 19(total:35) | 4(total:21) |
| Age | 100 (29, 229) days | 127 (26, 305) days |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 19 (54%) | 4 (19%) |
