| Factor Information | |
|---|---|
| Data ID | 1267 |
| Factor | Duration of intensive care stay |
| Description | In the current study, postoperative abnormal background pattern and the lack of return to SWC during the recording phase were strongly related to poorer neurodevelopmental outcome at 4 years of age and were independent of potential confounding factors such as length of intensive care stay and mechanical ventilation as well as multiple bypass surgeries. |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To evaluate the predictive value of pre- and postoperative amplitude-integrated electroencephalography (aEEG) on neurodevelopmental outcomes in children operated for congenital heart disease (CHD). |
| p Value | 0.03 |
| Conclusion | aEEG is a useful bedside tool that helps to predict outcome in infants undergoing open-heart surgery for CHD. Abnormal postoperative background pattern and lack of return to SWCs are markers for subsequent impaired cognitive development. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 27453368 |
| Year | 2016 |
| Title | Postoperative Amplitude-Integrated Electroencephalography Predicts Four-Year Neurodevelopmental Outcome in Children with Complex Congenital Heart Disease. |
| Sample | ||
|---|---|---|
| Population | infants | |
| Source | amplitude-integrated electroencephalography (aEEG) | |
| Region | Zurich, Switzerland | |
| Method | amplitude-integrated electroencephalography (aEEG) | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | cardiac surgery with cardiopulmonary bypass | |
| Group | Amplitude-integrated electroencephalography (aEEG) abnormal (burst suppression, continuous low voltage, flat tracing)(Treatment) | aEEG normal (Continuous normal voltage, Discontinuous normal voltage)(Control) |
| Number | 7 | 53 |
| Age | 39.45 (30.6-41.9) weeks | 39.45 (30.6-41.9) weeks |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 26 (10-39) days | 11 (4-156) days |
