| Factor Information | |
|---|---|
| Data ID | 1269 |
| Factor | Return to SWC (Sleep-wake cycle) |
| Description | After we controlled for surgical and postoperative risk factors, abnormal postoperative background pattern and lack of return to sleep-wake cycles (SWCs) independently predicted poorer intelligence quotient at 4 years (P = .03 and P = .04 respectively) but was not related to motor outcome. |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | intelligence quotient at 4 years |
| p Value | <0.05 |
| Conclusion | aEEG is a useful bedside tool that helps to predict outcome in infants undergoing open-heart surgery for CHD. Abnormal postoperative background pattern and lack of return to SWCs are markers for subsequent impaired cognitive development. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 27453368 |
| Year | 2016 |
| Title | Postoperative Amplitude-Integrated Electroencephalography Predicts Four-Year Neurodevelopmental Outcome in Children with Complex Congenital Heart Disease. |
| Sample | ||
|---|---|---|
| Population | infants | |
| Source | amplitude-integrated electroencephalography (aEEG) | |
| Region | Zurich, Switzerland | |
| Method | amplitude-integrated electroencephalography (aEEG) | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | cardiac surgery with cardiopulmonary bypass | |
| Group | No return to SWC(Treatment) | Return to SWC(Control) |
| Number | 14 | 34 |
| Age | 39.45 (30.6-41.9) weeks | 39.45 (30.6-41.9) weeks |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | Total IQ: 88.5 (56-114) | Total IQ: 101 (74-135) |
