| Factor Information | |
|---|---|
| Data ID | 1275 |
| Factor | reintervention age |
| Description | Reintervention occurred in 6.7% of patients (41/633) and was higher in children than adults (hazard ratio, 4.8). Bioprosthetic pulmonary valve replacement in patients with congenital heart disease has excellent short-term outcomes, but children have an approximately 5-fold greater risk of reintervention than adults |
| Biomarker | NA |
| Classification | E1 (physiological factor - age) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | Reintervention |
| p Value | <0.001 |
| OR | 4.85 |
| Conclusion | Bioprosthetic pulmonary valve replacement in patients with congenital heart disease has excellent short-term outcomes, but children have an approximately 5-fold greater risk of reintervention than adults. Independently of age, reintervention rates vary by valve type. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 511 |
| CHD Type | isolated CHD |
| CHD Subtype | TOF/CAVC/PS/PA |
| Reference | |
|---|---|
| PMID | 27637422 |
| Year | 2016 |
| Title | Outcome and performance of bioprosthetic pulmonary valve replacement in patients with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | children and adults | |
| Source | Data | |
| Region | Boston, United States | |
| Method | Kaplan–Meier estimation and Cox proportional hazards regression methodologies | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | surgical bioprosthetic pulmonary valve replacement | |
| Group | Children(Treatment) | Adults(Control) |
| Number | 307 | 304 |
| Age | ＜18 year | > 18 year |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | Reintervention (surgical or catheter-based Melody valve placement), no. : 32/307 (10.4%) | Reintervention (surgical or catheter-based Melody valve placement), no. : 9/304 (3.0%) |
