| Factor Information | |
|---|---|
| Data ID | 1287 |
| Factor | prevalence of severe CHD(mothers with congenital heart defects) |
| Description | The same pattern held for mild forms of congenital heart disease. A higher prevalence of severe congenital heart disease was seen only among offspring of mothers with congenital heart defects or type 2 diabetes. |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | A higher prevalence of severe congenital heart disease was seen only among offspring |
| OR | 6.72 |
| Conclusion | The children of women with several kinds of chronic disease appear to be at risk for congenital heart disease. Preconception counselling and optimum treatment of pregnant women with chronic disease would seem prudent. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 512 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD/PDA/VSD/PS/CoA/ECD/AS/EA/other/TOF/TGA/DORV/TAPVR/Common ventricle/HLHS/Common truncus/TA/ccTGA |
| Reference | |
|---|---|
| PMID | 27729382 |
| Year | 2016 |
| Title | Association of maternal chronic disease with risk of congenital heart disease in offspring |
| Sample | ||
|---|---|---|
| Population | Mothers | |
| Source | Taiwan Maternal and Child Health Database | |
| Region | Taiwan, China | |
| Method | multivariable logistic regression analysis | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | mothers with Congenital heart defects(Treatment) | mothers without Congenital heart defects(Control) |
| Number | N/A | N/A |
| Age | N/A | N/A |
| Gender (Male: Female) | Femal | N/A |
| Marker Level | Prevalence per 1000 live births (95% CI) =9.0 (5.3–14.5) | Prevalence per 1000 live births (95% CI) =1.3 (1.2–1.4) |
