| Factor Information | |
|---|---|
| Data ID | 1323 |
| Factor | hippocampal volumes |
| Description | hippocampal volumes were significantly different between CHD patients(6.6 ml SD 0.7) and controls (7.3 ml SD 0.8) within this subgroup (P=0.003) |
| Biomarker | NA |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | lower total hippocampal volumes |
| p Value | 0.003 |
| Conclusion | Hippocampal volumes were significantly different between CHD patients with or without lesions and control.Adolescents with CHD had 10% lower total hippocampal volumes compared with controls. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 517 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD, VSD/non C-CHD/TGA/other |
| Reference | |
|---|---|
| PMID | 27356084 |
| Year | 2016 |
| Title | Hippocampal volume reduction is associated with intellectual functions in adolescents with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Adolescents | |
| Source | N/A | |
| Region | Zurich, Switzerland | |
| Method | neurocognitive testing and cerebral magnetic resonance imaging | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | early cardiopulmonary bypass surgery | |
| Group | Adolescents with CHD without lesions(Treatment) | controls(Control) |
| Number | 39 | 32 |
| Age | mean age: 13.8 years | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 6.6±0.7ml | 7.3±0.8ml |
