| Factor Information | |
|---|---|
| Data ID | 1325 |
| Factor | total IQ in CHD patients |
| Description | After controlling for total brain volume, total hippocampal volume correlated with total IQ, with working memory, and verbal comprehension in CHD patients, but not in controls. |
| Biomarker | NA |
| Classification | F5 (psychosocial factor - intelligence) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | total hippocampal volume |
| p Value | 0.003 |
| Conclusion | In adolescent survivors of cardiopulmonary bypass surgery for CHD, specific brain regions such as the hippocampus may show long-term persistent alteration and correlate with intellectual deficits, particularly with verbal and memory functions. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 517 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD, VSD/non C-CHD/TGA/other |
| Reference | |
|---|---|
| PMID | 27356084 |
| Year | 2016 |
| Title | Hippocampal volume reduction is associated with intellectual functions in adolescents with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Adolescents | |
| Source | N/A | |
| Region | Zurich, Switzerland | |
| Method | neurocognitive testing and cerebral magnetic resonance imaging | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | early cardiopulmonary bypass surgery | |
| Group | CHD without lesions(Treatment) | controls(Control) |
| Number | 39 | 32 |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | N/A | N/A |
