Factor Information
Data ID 1328
Factor QRS duration
Description In both SCD cases and controls, QRS duration increased significantly over time: 1.6±0.5 ms/year in SCD cases and 0.5±0.2 ms/year in controls (P = 0.011, see Supplementary material online, Figure S1).
Biomarker NA
Classification E4 (physiological factor - cardiac function parameter)
Association
Application prognosis
Objective The purpose of the current study was to investigate whether changes over time in electrocardiographic and echocardiographic parameters may enhance prediction of SCD
p Value 0.011
Conclusion In adults with CHD, QRS duration and ventricular dysfunction progress over time. Progression of QRS duration and the rate of impairment of ventricular function served to identify those at increased risk of SCD.
Risk Factor unknown
CHD Type
ID 518
CHD Type isolated CHD
CHD Subtype ES/TGA/TOF/LSOD/ASD/VSD/AVSD/Cyanotic non-ES/EA/other
Reference
PMID 27247006
Year 2016
Title Sudden cardiac death in adult congenital heart disease: can the unpredictable be foreseen?
Sample
Population Adults
Source three databases
Region Amsterdam & Utrecht, Netherlands
Method Sequential measurements were performed on electrocardiograms and echocardiograms.
Race Europe
Disease History N/A
Treatment History N/A
Group Sudden cardiac death (SCD) cases(Treatment) control cases(Control)
Number 131 260
Age mean age: 36+14 years mean age: 37+13 years
Gender (Male: Female) 88:43 165:95
Marker Level QRS: 1.6±0.5 ms/year QRS: 0.5±0.2 ms/year