| Factor Information | |
|---|---|
| Data ID | 1331 |
| Factor | Change from any baseline systemic ventricular function to severe ventricular dysfunction over time |
| Description | To access wether change from any baseline systemic ventricular function (normal, mild, or moderately impaired) to severe ventricular dysfunction over time was associated with the highest risk of SCD |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | Change from any baseline systemic ventricular function (normal, mild, or moderately impaired) to severe ventricular dysfunction over time was associated with the highest risk of SCD |
| p Value | 0.008 |
| OR | 16.9 |
| Conclusion | In adults with CHD, QRS duration and ventricular dysfunction progress over time. Progression of QRS duration and the rate of impairment of ventricular function served to identify those at increased risk of SCD. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 518 |
| CHD Type | isolated CHD |
| CHD Subtype | ES/TGA/TOF/LSOD/ASD/VSD/AVSD/Cyanotic non-ES/EA/other |
| Reference | |
|---|---|
| PMID | 27247006 |
| Year | 2016 |
| Title | Sudden cardiac death in adult congenital heart disease: can the unpredictable be foreseen? |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | three databases | |
| Region | Amsterdam & Utrecht, Netherlands | |
| Method | Sequential measurements were performed on electrocardiograms and echocardiograms. | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Sudden cardiac death (SCD) cases(Treatment) | control cases(Control) |
| Number | 131 | 260 |
| Age | mean age: 36+14 years | mean age: 37+13 years |
| Gender (Male: Female) | 88:43 | 165:95 |
| Marker Level | 0.099 | 0.005 |
