| Factor Information | |
|---|---|
| Data ID | 1413 |
| Factor | change in apparent diffusion coefficient(ADC) of grey matter |
| Description | The prenatal diagnosis group had a faster rate of decrease in ADC as compared with the postnatal diagnosis group (0.6% increase in the dif- ference with each week of increase in age; 95% CI, 0.1%-1.2%; P=0.02) |
| Biomarker | NA |
| Classification | A6 (clinical factor - other) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | neonate with CHD |
| p Value | 0.02 |
| Conclusion | Patients with prenatal diagnose demonstrated faster brain development in gray matter apparent diffusion coefficient. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 525 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TGA/TGA, VSD/AAO/PO |
| Reference | |
|---|---|
| PMID | 26902528 |
| Year | 2016 |
| Title | Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury. |
| Sample | ||
|---|---|---|
| Population | neonates | |
| Source | data | |
| Region | Canda,British Columbia | |
| Method | Linear regression analysis | |
| Race | American | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | prenatal diagnosis(Treatment) | postnatal diagnosis(Control) |
| Number | 67 | 86 |
| Age | N/A | N/A |
| Gender (Male: Female) | 44:23 | 58:28 |
| Marker Level | 0.6% (0.6% increase in the dif- ference with each week of increase in age) | N/A |
