| Factor Information | |
|---|---|
| Data ID | 1515 |
| Factor | GDF-15 level in different NYHA functional class |
| Description | N/A |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | diagnosis and prognosis |
| Objective | Correlations between GDF-15 and other biomarkers in CHD |
| p Value | <0.001 |
| Conclusion | Higher GDF-15 was associated with worsening NYHA functional class. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 537 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | AS/AC/TOF/TGA/ccTGA/NA/PAH/TGA, VSD, DORV |
| Reference | |
|---|---|
| PMID | 26402453 |
| Year | 2016 |
| Title | Release of growth-differentiation factor 15 and associations with cardiac function in adult patients with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | adult | |
| Source | blood | |
| Region | Netherlands,Rotterdam | |
| Method | χ2-test or Fisher’s exact test | |
| Race | European | |
| Disease History | N/A | |
| Treatment History | cardiac surgery | |
| Group | NYHA II; NYHA III(Treatment) | NYHA I(Control) |
| Number | N/A | N/A |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 864(614-1697)ng/L(NYHA II); 2533(2161-3951)ng/L(NYHA III) | 601(479-810)ng/L |
