| Factor Information | |
|---|---|
| Data ID | 1533 |
| Factor | Medication--b-Blockers |
| Description | baseline demographic data, information on disease complexity, underlying cardiac diagnosis, NYHA functional class, cardiac medication as well as selected ECG parameters for the overall population and the two subgroups of patients on ADDs (Group A) and not on ADDs (Group B). |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To examine the number of ACHD patients treated with antidepressant drugs (ADDs) at a tertiary centre, identify predictors of ADD use and test the hypothesis that severe depression requiring ADD therapy is directly or indirectly related to a worse outcome in this growing population. |
| p Value | 0.0001 |
| Conclusion | It provides baseline demographic data, information on disease complexity, underlying cardiac diagnosis, NYHA functional class, cardiac medication as well as selected ECG parameters for the overall population and the two subgroups of patients on ADDs (Group A) and not on ADDs (Group B). |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 538 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD/VSD/AVSD/CoA/TOF/TGA/ccTGA/EA/ES/other |
| Reference | |
|---|---|
| PMID | 26314687 |
| Year | 2016 |
| Title | Depression requiring anti-depressant drug therapy in adult congenital heart disease: prevalence, risk factors, and prognostic value. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | a retrospective study | |
| Region | London, UK | |
| Method | The entire ACHD cohort under active follow-up at the Royal Brompton Hospital between 2000 and 2011 was identified based on an electronic database search and was included in the analysis. | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | ADD therapy | |
| Group | Group A: patients on antidepressant drugs, ADDs(Treatment) | Group B: patients not on antidepressant drugs, ADDs(Control) |
| Number | 26 | 375 |
| Age | 36.1±15.5 years | 30.2±16.4 years |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 0.127 | 0.063 |
