| Factor Information | |
|---|---|
| Data ID | 1546 |
| Factor | survival propability |
| Description | Uni- and multivariate predictors of the need for anti-depressant drugs on logistic regression analysis |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To examine the number of ACHD patients treated with antidepressant drugs (ADDs) at a tertiary centre, identify predictors of ADD use and test the hypothesis that severe depression requiring ADD therapy is directly or indirectly related to a worse outcome in this growing population. |
| p Value | 0.002 |
| HR | 1.44 |
| Conclusion | The results of the bootstrap analyses showed that even after accounting for differences in baseline characteristics, males had an HR of death of 1.44 (95% CI 1.17–1.84) compared with men not requiring ADD. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 538 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | ASD/VSD/AVSD/CoA/TOF/TGA/ccTGA/EA/ES/other |
| Reference | |
|---|---|
| PMID | 26314687 |
| Year | 2016 |
| Title | Depression requiring anti-depressant drug therapy in adult congenital heart disease: prevalence, risk factors, and prognostic value. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | a retrospective study | |
| Region | London, UK | |
| Method | univariate analysis; multivariate analysis | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | ADD therapy | |
| Group | Group A: patients on antidepressant drugs, ADDs(Treatment) | Group B: patients not on antidepressant drugs, ADDs(Control) |
| Number | 204 | 5958 |
| Age | 36.1±15.5 years | 30.2±16.4 years |
| Gender (Male: Female) | 136:68 | 2943:3015 |
| Marker Level | N/A | N/A |
