| Factor Information | |
|---|---|
| Data ID | 1548 |
| Factor | P-selectin candidate gene SNPs---827T/C:CT |
| Description | Compared with the patients with TT genotype, the risk of PAH-CHD was decreased by 47% in subjects with CT genotypes (OR=0.43, 95% CI=0.22-0.96). |
| Biomarker | NA |
| Classification | D1 (molecular factor - DNA) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | Relationship between P-selectin gene polymorphism and PAH-CHD |
| p Value | 0.027 |
| Conclusion | Compared with the patients with TT genotype, the risk of PAH-CHD was decreased by 47% in subjects with CT genotypes (OR=0.43, 95% CI=0.22-0.96). |
| Risk Factor | protective factor |
| CHD Type | |
|---|---|
| ID | 539 |
| CHD Type | isolated CHD |
| CHD Subtype | ASD/PDA/VSD |
| Reference | |
|---|---|
| PMID | 26261613 |
| Year | 2015 |
| Title | P-selectin gene polymorphism associates with pulmonary hypertension in congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | adolescents and adults | |
| Source | blood | |
| Region | Nantong, China | |
| Method | case-control correlation analysis | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | PAH-CHD patients(P-selectin gene 826CT)(Treatment) | controls(P-selectin gene 826CT)(Control) |
| Number | 7 | 55 |
| Age | 31 (17.66) years | 33 (16.3) years |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 7 (12.07%) | 55 (26.83%) |
