| Factor Information | |
|---|---|
| Data ID | 1552 |
| Factor | P-selectin candidate gene SNPs---827T/C:CT+CC |
| Description | P-selectin candidate gene SNPs was not correlated with the susceptibility of PAH-CHD (P>0.05). In addition, performing the analysis in patients with CHD and PAH-CHD, no significant correlation was observed in SNPs and disease susceptibility as well. |
| Biomarker | NA |
| Classification | D1 (molecular factor - DNA) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | Relationship between P-selectin gene polymorphism and PAH-CHD |
| p Value | 0.024 |
| OR | 0.36 |
| Conclusion | P-selectin candidate gene SNPs was not correlated with the susceptibility of PAH-CHD (P>0.05). In addition, performing the analysis in patients with CHD and PAH-CHD, no significant correlation was observed in SNPs and disease susceptibility as well. |
| Risk Factor | protective factor |
| CHD Type | |
|---|---|
| ID | 539 |
| CHD Type | isolated CHD |
| CHD Subtype | ASD/PDA/VSD |
| Reference | |
|---|---|
| PMID | 26261613 |
| Year | 2015 |
| Title | P-selectin gene polymorphism associates with pulmonary hypertension in congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | adolescents and adults | |
| Source | blood | |
| Region | Nantong, China | |
| Method | case-control correlation analysis | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | PAH-CHD patients(Treatment) | CHD patients(Control) |
| Number | 7 | 13 |
| Age | 31 (17.66) years | 32 (18.91) years |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 7 (12.07%) | 13 (30.23%) |
