| Factor Information | |
|---|---|
| Data ID | 1555 |
| Factor | P-selectin expression in different SNPs in PAH-CHD |
| Description | plasma P-selectin level was markedly higher in PAH-CHD patients with -825T/C TT genotype than the patients with TC+CC genotype (19.75±1.02 ng/ml vs. 14.53±1.48 ng/ml). The similar results were also found in CHD patients and healthy subjects. |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | Relationship between P-selectin gene polymorphism and PAH-CHD |
| p Value | 0.0011 |
| Conclusion | Plasma P-selectin level was markedly higher in PAH-CHD patients with -825T/C TT genotype than the patients with TC+CC genotype (19.75±1.02 ng/ml vs. 14.53±1.48 ng/ml). The similar results were also found in CHD patients and healthy subjects. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 539 |
| CHD Type | isolated CHD |
| CHD Subtype | ASD/PDA/VSD |
| Reference | |
|---|---|
| PMID | 26261613 |
| Year | 2015 |
| Title | P-selectin gene polymorphism associates with pulmonary hypertension in congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | adolescents and adults | |
| Source | blood | |
| Region | Nantong, China | |
| Method | case-control correlation analysis | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | PAH-CHD patients(P-selectin gene 826TT)(Treatment) | PAH-CHD patients(P-selectin gene 826TC+CC)(Control) |
| Number | 37 | 37 |
| Age | 31 (17.66) years | 31 (17.66) years |
| Gender (Male: Female) | 26:32 | 26:32 |
| Marker Level | TT: 19.75±1.02 ng/ml | TC+CC: 14.53±1.48 ng/ml |
