| Factor Information | |
|---|---|
| Data ID | 1556 |
| Factor | P-selectin expression in different SNPs in CHD |
| Description | plasma P-selectin level was markedly higher in CHD patients with -825T/C TT genotype than the patients with TC+CC genotype (15.46±0.58 ng/ml vs. 11.45±0.95 ng/ml). |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | Relationship between P-selectin gene polymorphism and PAH-CHD |
| p Value | 0.0079 |
| Conclusion | Plasma P-selectin level was markedly higher in CHD patients with -825T/C TT genotype than the patients with TC+CC genotype (15.46±0.58 ng/ml vs. 11.45±0.95 ng/ml). |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 539 |
| CHD Type | isolated CHD |
| CHD Subtype | ASD/PDA/VSD |
| Reference | |
|---|---|
| PMID | 26261613 |
| Year | 2015 |
| Title | P-selectin gene polymorphism associates with pulmonary hypertension in congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | adolescents and adults | |
| Source | blood | |
| Region | Nantong, China | |
| Method | case-control correlation analysis | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | CHD patients(P-selectin gene 826TT)(Treatment) | CHD patients(P-selectin gene 826TC+CC)(Control) |
| Number | 26 | 26 |
| Age | 32 (18.91) years | 32 (18.91) years |
| Gender (Male: Female) | 20:23 | 20:23 |
| Marker Level | TT: 15.46±0.58ng/ml | TC+CC: 11.45±0.95 ng/ml |
