| Factor Information | |
|---|---|
| Data ID | 1557 |
| Factor | P-selectin expression in different SNPs in controls |
| Description | plasma P-selectin level was markedly higher in healthy subjects with -825T/C TT genotype than the patients with TC+CC genotype (15.07±0.47 ng/ml vs. 20.30±3.48 ng/ml). |
| Biomarker | NA |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | Relationship between P-selectin gene polymorphism and PAH-CHD |
| p Value | 0.0003 |
| Conclusion | Plasma P-selectin level was markedly higher in healthy subjects with -825T/C TT genotype than the patients with TC+CC genotype (15.07±0.47 ng/ml vs. 20.30±3.48 ng/ml). |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 539 |
| CHD Type | isolated CHD |
| CHD Subtype | ASD/PDA/VSD |
| Reference | |
|---|---|
| PMID | 26261613 |
| Year | 2015 |
| Title | P-selectin gene polymorphism associates with pulmonary hypertension in congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | adolescents and adults | |
| Source | blood | |
| Region | Nantong, China | |
| Method | case-control correlation analysis | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | control(P-selectin gene 826TT)(Treatment) | control(P-selectin gene 826TC+CC)(Control) |
| Number | 35 | 35 |
| Age | 33 (16.3) years | 33 (16.3) years |
| Gender (Male: Female) | 102:103 | 102:103 |
| Marker Level | TT: 15.07±0.47ng/ml | TC+CC: 20.30±3.48 ng/ml |
