| Factor Information | |
|---|---|
| Data ID | 160 |
| Factor | Pregnancies complicated by CHD with aortic obstruction (AO) |
| Description | Pregnancies complicated by CHD with aortic obstruction (AO) were significantly more likely than those with no obstruction to have abnormal placental pathology (79% vs. 44%). |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | abnormal placental pathology |
| p Value | 0.007 |
| OR | 6.79 |
| Conclusion | These data suggest that placental abnormalities are common in CHD and may have a compounding effect on brain lesions in this high-risk population. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 417 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | DIVM/DIVM, other |
| Reference | |
|---|---|
| PMID | 30858514 |
| Year | 2019 |
| Title | Placental Pathology and Neuroimaging Correlates in Neonates with Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | Neonates | |
| Source | recruited cases and controls; placenta | |
| Region | Washington, USA | |
| Method | a single-center, prospective, observational study | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Aortic obstruction(Treatment) | No aortic obstruction(Control) |
| Number | 18 | 33 |
| Age | Gestational age (median): 38.7 months | Gestational age (median): 38.7 months |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 0.79 | 0.44 |
