| Factor Information | |
|---|---|
| Data ID | 161 |
| Factor | Head circumference |
| Description | When groups were subdivided into cohorts based upon type of placental pathology, signfcantly higher infant head circumference was noted in the group with histologic chorioamnionitis compared to no placental abnormalities. |
| Biomarker | NA |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | abnormal placental pathology |
| p Value | 0.04 |
| Conclusion | These data suggest that placental abnormalities are common in CHD and may have a compounding effect on brain lesions in this high-risk population. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 421 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TGA, IVS/TGA, VSD/TOF/TOF, PA/TA/TAPVC/EA/VSD, IAA/CoA, HAA/other/PA, IVS/HLHS/DORV/CoA |
| Reference | |
|---|---|
| PMID | 30858514 |
| Year | 2019 |
| Title | Placental Pathology and Neuroimaging Correlates in Neonates with Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | Neonates | |
| Source | recruited cases and controls; placenta | |
| Region | Washington, USA | |
| Method | a single-center, prospective, observational study | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | placental abnormality of histologic chorioamnionitis(Treatment) | no placental abnormalities(Control) |
| Number | 29 (Placental pathology: Abnormal 57%) | 22 (Placental pathology: Normal 43%) |
| Age | Gestational age (median): 38.7 months | Gestational age (median): 38.9 months |
| Gender (Male: Female) | 19:10 | 13:9 |
| Marker Level | 36 | 33.9 |
