| Factor Information | |
|---|---|
| Data ID | 163 |
| Factor | normal placenta |
| Description | Normal placentas with aortic obstruction cases appear to be smaller than those with no aortic obstruction cases. |
| Biomarker | NA |
| Classification | E11 (physiological factor - physical sign) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | abnormal placental pathology |
| Conclusion | Pregnancies complicated by CHD with aortic obstruction were signicantly more likely than those with no obstruction to have abnormal placental pathology (83% vs. 42%). The odds of abnormal placental pathology were 6.79 times higher among pregnancies com- plicated by CHD with aortic obstruction compared to those without |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 421 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TGA, IVS/TGA, VSD/TOF/TOF, PA/TA/TAPVC/EA/VSD, IAA/CoA, HAA/other/PA, IVS/HLHS/DORV/CoA |
| Reference | |
|---|---|
| PMID | 30858514 |
| Year | 2019 |
| Title | Placental Pathology and Neuroimaging Correlates in Neonates with Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | Neonates | |
| Source | recruited cases and controls; placenta | |
| Region | Washington, USA | |
| Method | a single-center, prospective, observational study | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | aortic obstruction cases(Treatment) | no aortic obstruction cases(Control) |
| Number | 3 | 19 |
| Age | Gestational age (median): 38.7 months | Gestational age (median): 38.7 months |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 0.17 | 0.58 |
