| Factor Information | |
|---|---|
| Data ID | 1649 |
| Factor | Brain cortical development--Left cingulate fissure depth/BPD |
| Description | Results of magnetic resonance imaging (MRI) of brain at term in fetuses with CHD and controls |
| Biomarker | NA |
| Classification | A6 (clinical factor - other) |
| Association | |
|---|---|
| Application | prognosis and diagnosis |
| Objective | Our aim was to evaluate whether brain development in late pregnancy can be predicted by fetal brain Doppler, head biometry and the clinical form of CHD at the time of diagnosis. |
| p Value | <0.01 |
| Conclusion | Furthermore, when we evaluated cortical sulcation, CHD fetuses presented significantly decreased depths for left and right parietoccipital, cingulate and calcarine fissures compared to those of controls. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 547 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | AVSD/TOF/TGV/TA/HLHS/AOS/HAA/TA/EA/PS, PA/NA |
| Reference | |
|---|---|
| PMID | 26053596 |
| Year | 2016 |
| Title | Mid-gestation brain Doppler and head biometry in fetuses with congenital heart disease predict abnormal brain development at birth. |
| Sample | ||
|---|---|---|
| Population | Fetuses | |
| Source | CHD fetus | |
| Region | Barcelona, Spain | |
| Method | a prospective cohort study | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | CHD fetuses(Treatment) | control fetuses(Control) |
| Number | 58 | 58 |
| Age | 37.2±0.4 weeks (GA at MRI) | 37.3±0.4 weeks (GA at MRI) |
| Gender (Male: Female) | 37:21 | 29:29 |
| Marker Level | 0.061±0.009 | 0.093±0.015 |
