Factor Information
Data ID 165
Factor moderate/severe brain leision
Description There was a trend towards more severe brain lesions in patients with abnormal placenta (55% moderate/severe with placental abnormality compared to 11% moderate/severe without placental abnormality).
Biomarker NA
Classification A3 (clinical factor - disease & symptom)
Association
Application prognosis
Objective moderate/severe brain leision
p Value <0.05
OR 9.61
Conclusion There was a trend towards more severe brain lesions in patients with abnormal placenta (55% moderate/severe with placental abnormality compared to 11% moderate/severe without placental abnormality).
Risk Factor risk factor
CHD Type
ID 421
CHD Type isolated CHD/non-isolated CHD
CHD Subtype TGA, IVS/TGA, VSD/TOF/TOF, PA/TA/TAPVC/EA/VSD, IAA/CoA, HAA/other/PA, IVS/HLHS/DORV/CoA
Reference
PMID 30858514
Year 2019
Title Placental Pathology and Neuroimaging Correlates in Neonates with Congenital Heart Disease
Sample
Population Neonates
Source recruited cases and controls; placenta
Region Washington, USA
Method a single-center, prospective, observational study
Race North America
Disease History N/A
Treatment History N/A
Group placental abnormality(Treatment) without placental abnormality(Control)
Number 16 2
Age Gestational age (median): 38.7 months Gestational age (median): 38.9 months
Gender (Male: Female) N/A N/A
Marker Level 0.55 0.11