CHDRFKB

Factor Information
Data ID	1676
Factor	Occupation
Description	There were significant differences in the gender of children, occupation of the mothers, family history with CHD, history of abortion, history of adverse pregnancy, early pregnancy health, fetus during pregnancy, pesticide exposure and drug exposure in two groups (P < 0.05 for both comparisons).
Biomarker	NA
Classification	F6 (psychosocial factor - other)

Association
Application	risk assessment
Objective	The aim of this study is to evaluate the relevant risk-factors of children with CHD and their mothers.
p Value	<0.001
Conclusion	There were significant differences in the gender of children, occupation of the mothers, family history with CHD, history of abortion, history of adverse pregnancy, early pregnancy health, fetus during pregnancy, pesticide exposure and drug exposure in two groups (P < 0.05 for both comparisons).
Risk Factor	unknown

Reference
PMID	26035828
Year	2015
Title	Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease

Sample
Population	mothers
Source	questionnaire
Region	Nanjing, China
Method	relevant risk-factors of children with CHD and their mothers
Race	Asian
Disease History	History of CHD/abortion/adverse pregnancy
Treatment History	N/A
Group	mother of CHD children(Treatment)	mother of control children(Control)
Number	Farmer 34 ;Worker 36; Server 17 ; Businessman 12;Government worker 3 ;Others 55	Farme92 ;Worker 27 ; Server ; Businessman14; Government worker 3; Others 37
Age	26.16±4.69 years	25.39±3.28 years
Gender (Male: Female)	0:100%	0:100%
Marker Level	Farmer34 (21.66%) ;Worker36 (22.93%); Server 17 (10.83%); Businessman 12(7.64%) ;Government worker 3(1.91%) ;Others 55 (35.03%)	Farme92 (51.99%) ;Worker 27 (15.25%); Server 4(2.26%); Businessman14(7.91%); Government worker 3(1.69%); Others 37(20.90%)