| Factor Information | |
|---|---|
| Data ID | 1684 |
| Factor | SNPs in mothers: MTHFR gene rs1801131:AA |
| Description | Logistic regression analyses adjusted for gender of children, occupation of mothers, family history with CHD, history of abortion, history of adverse pregnancy, early pregnancy health, fetus during pregnancy, pesticide exposure and drug exposure |
| Biomarker | NA |
| Classification | D1 (molecular factor - DNA) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | The aim of this study is to evaluate the relevant risk-factors of children with CHD and their mothers. |
| OR | 1 |
| Conclusion | N/A |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 26035828 |
| Year | 2015 |
| Title | Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | mothers | |
| Source | questionnaire | |
| Region | Nanjing, China | |
| Method | Logistic regression analyses | |
| Race | Asian | |
| Disease History | History of CHD/abortion/adverse pregnancy | |
| Treatment History | N/A | |
| Group | mother of CHD children(Treatment) | mother of control children(Control) |
| Number | 95 | 157 |
| Age | 26.16±4.69 years | 25.39±3.28 years |
| Gender (Male: Female) | 0:95 | 0:157 |
| Marker Level | 95(62.09%) | 157(72.68%) |
