| Factor Information | |
|---|---|
| Data ID | 1688 |
| Factor | relationship between in matching pair mother and chlidren:rs 1801131 AA(mother) |
| Description | hereditary analysis |
| Biomarker | NA |
| Classification | D1 (molecular factor - DNA) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | The aim of this study is to evaluate the relevant risk-factors of children with CHD and their mothers. |
| p Value | <0.001 |
| Conclusion | It was observed that the five SNPs in mothers were significantly associated with the SNPs in their offspring (P < 0.001) |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 26035828 |
| Year | 2015 |
| Title | Study on Environmental Causes and SNPs of MTHFR, MS and CBS Genes Related to Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | mothers | |
| Source | questionnaire | |
| Region | Nanjing, China | |
| Method | hereditary analysis | |
| Race | Asian | |
| Disease History | History of CHD/abortion/adverse pregnancy | |
| Treatment History | N/A | |
| Group | offspring with genotype of 1801131 AA(Treatment) | offspring with genotype of 1801131 AC+CC(Control) |
| Number | 188 | 48 |
| Age | N/A | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 188(78.66%) | 48(21.34%) |
