| Factor Information | |
|---|---|
| Data ID | 1710 |
| Factor | correlations: Acylated ghrelin--PADP |
| Description | PASP, PADP, RVSP, mPAP, RVDT, and PAD were positively correlated with plasma-acylated ghrelin levels. |
| Biomarker | YES |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | This study aims to estimate plasma levels of acylated ghrelin in children with pulmonary hypertension (PH) associated with congenital heart disease (CHD) and to correlate the levels of acylated ghrelin with endothelin-1 (ET-1), nitric oxide (NO), and clinical hemodynamic parameters. |
| p Value | 0.004 |
| Conclusion | Increased acylated ghrelin levels correlated positively with ET-1, NO, PASP, PADP, RVSP, mPAP, RVD, and PAD. Acylated ghrelin may be a new biomarker of PH-CHD. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 548 |
| CHD Type | isolated CHD |
| CHD Subtype | VSD/ASD/PDA/other |
| Reference | |
|---|---|
| PMID | 25981561 |
| Year | 2015 |
| Title | Plasma Levels of Acylated Ghrelin in Children with Pulmonary Hypertension Associated with Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Luzhou, China | |
| Method | N/A | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | right heart catheterization | |
| Group | CHD-PAH children(Treatment) | N/A(Control) |
| Number | N/A | N/A |
| Age | 35.9 ± 20.9 months | N/A |
| Gender (Male: Female) | 13:7 | N/A |
| Marker Level | r=0.613 | N/A |
