Factor Information
Data ID 1794
Factor the peak velocity of tricuspid regurgitation, TRV (m/s)
Description The main pulmonary artery diameter and the peak velocity of tricuspid regurgitation were higher in CHD patients with severe PAH than in controls and CHD patients without PAH (P<0.05).
Biomarker NA
Classification E10 (physiological factor - other)
Association
Application diagnosis
Objective we investigated whether ADMA could help specifically identify the disease in a relatively large sample size of CHD patients.
p Value <0.05
Conclusion The main pulmonary artery diameter and the peak velocity of tricuspid regurgitation were higher in CHD patients with severe PAH than in controls and CHD patients without PAH (P<0.05).
Risk Factor unknown
CHD Type
ID 390
CHD Type isolated CHD
CHD Subtype VSD/ASD/PDA
Reference
PMID 25737007
Year 2015
Title Asymmetric Dimethyl-L-Arginine is a Biomarker for Disease Stage and Follow-Up of Pulmonary Hypertension Associated with Congenital Heart Disease.
Sample
Population PAH-CHD patients
Source a single-center prospective observational study
Region Changsha, China
Method Plasma ADMA levels were measured by enzyme-linked immunosorbent assay.
Race Asian
Disease History N/A
Treatment History N/A
Group Group B:CHD with mild-to-moderate PAH)(Treatment) HCG:healthy control group(Control)
Number 20 20
Age 31.36 ± 10.5 years 31.3 ± 6.5 years
Gender (Male: Female) 3:17 5:15
Marker Level 3.00 ± 1.3 m/s 2.6 ± 0.5 m/s