| Factor Information | |
|---|---|
| Data ID | 1803 |
| Factor | MPAP (mmHg) |
| Description | The measurements for pulmonary artery systolic pressure, pulmonary artery diastolic pressure, pulmonary artery pressure, right atrial pressure, and right ventricular pressure were significantly higher in CHD patients with severe PAH and CHD patients with mild-to-moderate PAH than in CHD patients without PAH (P<0.05). |
| Biomarker | NA |
| Classification | E9 (physiological factor - hemodynamic parameter) |
| Association | |
|---|---|
| Application | diagnosis |
| Objective | we investigated whether ADMA could help specifically identify the disease in a relatively large sample size of CHD patients. |
| p Value | <0.001 |
| Conclusion | The measurements for pulmonary artery systolic pressure, pulmonary artery diastolic pressure, pulmonary artery pressure, right atrial pressure, and right ventricular pressure were significantly higher in CHD patients with severe PAH and CHD patients with mild-to-moderate PAH than in CHD patients without PAH (P<0.05). |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 390 |
| CHD Type | isolated CHD |
| CHD Subtype | VSD/ASD/PDA |
| Reference | |
|---|---|
| PMID | 25737007 |
| Year | 2015 |
| Title | Asymmetric Dimethyl-L-Arginine is a Biomarker for Disease Stage and Follow-Up of Pulmonary Hypertension Associated with Congenital Heart Disease. |
| Sample | ||
|---|---|---|
| Population | PAH-CHD patients | |
| Source | a single-center prospective observational study | |
| Region | Changsha, China | |
| Method | Plasma ADMA levels were measured by enzyme-linked immunosorbent assay. | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Group A:CHD without PAH(Treatment) | Group C:CHD with severe PAH(Control) |
| Number | 20 | 40 |
| Age | 34.0 ± 12.7 years | 27.5 ± 9.1 years |
| Gender (Male: Female) | 4:16 | 11:29 |
| Marker Level | 21.5 (18.75, 23.00)mmHg | 72.00 (58.00, 84.25)mmHg |
