| Factor Information | |
|---|---|
| Data ID | 1823 |
| Factor | ADMA (umol/L) |
| Description | Comparisons among the subgroups of CHD patients with severe PAH showed that ADMA level was significantly higher in ES patients than in low PVR patients. |
| Biomarker | YES |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | diagnosis |
| Objective | we investigated whether ADMA could help specifically identify the disease in a relatively large sample size of CHD patients. |
| p Value | <0.001 |
| Conclusion | Comparisons among the subgroups of CHD patients with severe PAH showed that ADMA level was significantly higher in ES patients than in low PVR patients. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 390 |
| CHD Type | isolated CHD |
| CHD Subtype | VSD/ASD/PDA |
| Reference | |
|---|---|
| PMID | 25737007 |
| Year | 2015 |
| Title | Asymmetric Dimethyl-L-Arginine is a Biomarker for Disease Stage and Follow-Up of Pulmonary Hypertension Associated with Congenital Heart Disease. |
| Sample | ||
|---|---|---|
| Population | PAH-CHD patients | |
| Source | a single-center prospective observational study | |
| Region | Changsha, China | |
| Method | Plasma ADMA levels were measured by enzyme-linked immunosorbent assay. | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Low PVR(Treatment) | ES group(Control) |
| Number | 12 | 14 |
| Age | 27.67 ± 7.88 years | 27.50 ± 9.13 years |
| Gender (Male: Female) | 5:7 | 7:7 |
| Marker Level | 0.63 ± 0.18 umol/L | 0.87 ± 0.24 umol/L |
