Factor Information
Data ID 1825
Factor Age
Description Children in the AKI group were younger compared with non- AKI group (median age 5 vs. 99 days, P = .007).
Biomarker NA
Classification E1 (physiological factor - age)
Association
Application prognosis
Objective compared the performance of serum cystatin C (Cys C) and serum creatinine (Cr) as early markers of renal dysfunction in infants undergoing cardiac surgery under bypass
p Value 0.007
Conclusion Postoperative serum Cys C appears to be a more specific and sensitive biomarker for NGAL-positive AKI resulting from cardiopulmonary bypass surgery in infants undergoing cardiac surgery.
Risk Factor unknown
CHD Type
ID 148
CHD Type NA
CHD Subtype NA
Reference
PMID 25727405
Year 2015
Title Serum Cystatin C as an Early Marker of Neutrophil Gelatinase-associated Lipocalin-positive Acute Kidney Injury Resulting from Cardiopulmonary Bypass in Infants with Congenital Heart Disease
Sample
Population Infants
Source Serum
Region Dallas, USA
Method latex particle enhanced immunonephelometry using BN II System
Race North America
Disease History N/A
Treatment History cardiac surgery under cardiopulmonary bypass
Group infants with AKI(Treatment) non-AKI infants(Control)
Number 5 12
Age 5(4,16) days 99 (5, 272) days
Gender (Male: Female) Male 75% Male 60%
Marker Level meadian: 5 days meadian: 99 days