| Factor Information | |
|---|---|
| Data ID | 1827 |
| Factor | cardiopulmonary bypass (CPB) time (minutes) |
| Description | AKI group had longer durations of CPB (130 vs. 84 minutes, P = .01) |
| Biomarker | NA |
| Classification | A12 (clinical factor - treatment) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | compared the performance of serum cystatin C (Cys C) and serum creatinine (Cr) as early markers of renal dysfunction in infants undergoing cardiac surgery under bypass |
| p Value | 0.01 |
| Conclusion | Postoperative serum Cys C appears to be a more specific and sensitive biomarker for NGAL-positive AKI resulting from cardiopulmonary bypass surgery in infants undergoing cardiac surgery. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 25727405 |
| Year | 2015 |
| Title | Serum Cystatin C as an Early Marker of Neutrophil Gelatinase-associated Lipocalin-positive Acute Kidney Injury Resulting from Cardiopulmonary Bypass in Infants with Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | Infants | |
| Source | Serum | |
| Region | Dallas, USA | |
| Method | latex particle enhanced immunonephelometry using BN II System | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | cardiac surgery under cardiopulmonary bypass | |
| Group | infants with AKI(Treatment) | non-AKI infants(Control) |
| Number | 5 | 12 |
| Age | 5(4,16) days | 99 (5, 272) days |
| Gender (Male: Female) | Male 75% | Male 60% |
| Marker Level | 130(115,157) minutes | 84 (21,163)minutes |
