| Factor Information | |
|---|---|
| Data ID | 1831 |
| Factor | Urine output |
| Description | Urine output was a good marker of AKI on POD 1, with all patients in the non-AKI group having a urine output >1 mL/kg/hour and most patients in the AKI group <1 mL/kg/hour (P = .002) |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | compared the performance of serum cystatin C (Cys C) and serum creatinine (Cr) as early markers of renal dysfunction in infants undergoing cardiac surgery under bypass |
| p Value | 0.002 |
| Conclusion | Postoperative serum Cys C appears to be a more specific and sensitive biomarker for NGAL-positive AKI resulting from cardiopulmonary bypass surgery in infants undergoing cardiac surgery. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 148 |
| CHD Type | NA |
| CHD Subtype | NA |
| Reference | |
|---|---|
| PMID | 25727405 |
| Year | 2015 |
| Title | Serum Cystatin C as an Early Marker of Neutrophil Gelatinase-associated Lipocalin-positive Acute Kidney Injury Resulting from Cardiopulmonary Bypass in Infants with Congenital Heart Disease |
| Sample | ||
|---|---|---|
| Population | Infants | |
| Source | Serum | |
| Region | Dallas, USA | |
| Method | latex particle enhanced immunonephelometry using BN II System | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | cardiac surgery under cardiopulmonary bypass | |
| Group | infants with AKI(Treatment) | non-AKI infants(Control) |
| Number | 5 | 12 |
| Age | 5(4,16) days | 99 (5, 272) days |
| Gender (Male: Female) | 7:5 | 4:1 |
| Marker Level | urine output<1 mL/kg/hour | urine output >1 mL/kg/hour |
