| Factor Information | |
|---|---|
| Data ID | 1833 |
| Factor | troponin T (TnT) |
| Description | The preoperative concentration of high-sensitivity troponin T in children of the first year of life with congenital heart disease can be regarded as a predictor of postoperative complications. |
| Biomarker | YES |
| Classification | E2 (physiological factor - biochemical index) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | predictor of postoperative complication |
| p Value | <0.0001 |
| Conclusion | The diagnosis of myocardial ischemia using biochemical markers in the postoperative period is possible only by dynamic monitoring of the cardiac marker level. The preoperative concentration of high-sensitivity troponin T in children of the first year of life with congenital heart disease can be regarded as a predictor of postoperative complications. Highly sensitive TnT exceeding the level of 0.068 ng/ml can be regarded as a marker for postoperative complications in children of the first year of life before surgery. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 552 |
| CHD Type | isolated CHD |
| CHD Subtype | TOF/CAVC/TGA/VSD/TAPVR/ASD |
| Reference | |
|---|---|
| PMID | 25711661 |
| Year | 2015 |
| Title | Markers of myocardial damage in children of the first year of life with congenital heart disease in the early period after surgery with cardioplegic anoxia. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | plasma | |
| Region | Moscow, Russia | |
| Method | immunochemiluminescence method | |
| Race | Europe | |
| Disease History | N/A | |
| Treatment History | surgery with cardioplegic anoxia | |
| Group | all patients with peak excretion in 3-24 h postoperatively(Treatment) | Before surgery(Control) |
| Number | 45 | N/A |
| Age | mean age: 4.6 (2.2; 7.8) months | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 3.32 ng/ml (2.32; 4.78) | 0.03 ng/ml (0.0158; 0.067) |
