| Factor Information | |
|---|---|
| Data ID | 1869 |
| Factor | diagnosis of single-ventricle heart defect |
| Description | Risk factors associated with a significant increased odds of NEC (necrotizing enterocolitis) included a diagnosis of single-ventricle heart defect (OR 2.82; 95% CI 1.23, 6.49), although the overall risk in this population remained low (8/1,631, 0.5%). |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | odds of NEC |
| OR | >2.0 |
| Conclusion | The incidence of NEC in our cohort of infants with ductal-dependent CHD on PGE therapy was low and did not increase with enteral feeding |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 558 |
| CHD Type | isolated CHD |
| CHD Subtype | HLHS/TA/HRV/other/PS/CoA/TOF/IAA/PA/TGA/TA/AVS/EA/DORV |
| Reference | |
|---|---|
| PMID | 25486286 |
| Year | 2015 |
| Title | Necrotizing enterocolitis in infants with ductal-dependent congenital heart disease |
| Sample | ||
|---|---|---|
| Population | infants | |
| Source | N/A | |
| Region | Durham, USA | |
| Method | N/A | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | receiving prostaglandins | |
| Group | NEC(Treatment) | no NEC(Control) |
| Number | 8 (total: 21) | 1623 (total: 6689) |
| Age | < 28: 3 (14%); 28–34: 8 (38%); 35–36: 1 (5%); > 36: 9 (43%) | < 28: 80 (1%); 28–34: 696 (11%); 35–36: 799 (12%); > 36: 5,098 (76%) |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 8/21 (38%) | 1,623 (24%) |
