| Factor Information | |
|---|---|
| Data ID | 189 |
| Factor | number of Cardiovascular Risk factors(Low<2) |
| Description | There was significant residual risk of adverse cardiovascular events associated with ACHD after adjusting for conventional cardiovascular risk factors. |
| Biomarker | NA |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | Cardiovascular Risk factors |
| p Value | <0.001 |
| HR | 15.9 |
| Conclusion | In this analysis of ~500,000 British individuals from the UKB, we found a substantially higher burden of cardiovascular risk factors and disease incidence in individuals with lower complexity ACHD than in the general population. Furthermore, we estimated significant residual risk of adverse cardiovascular events associated with ACHD after adjusting for conventional cardiovascular risk factors. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 424 |
| CHD Type | isolated CHD |
| CHD Subtype | IAVD |
| Reference | |
|---|---|
| PMID | 30813762 |
| Year | 2019 |
| Title | Substantial Cardiovascular Morbidity in Adults With Lower-Complexity Congenital Heart Disease. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | data | |
| Region | San Francisco, USA | |
| Method | retrospectively and prospectively | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Isolated AoV defects(Treatment) | No ACHD(Control) |
| Number | 53 | 4739 |
| Age | median [IQR]: 59 [53,64] years | median [IQR]: 58 [50,63] years |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 53/159 | 4739/183464 |
