| Factor Information | |
|---|---|
| Data ID | 1901 |
| Factor | correlation between intestinal fatty acid–binding protein and VIS |
| Description | intestinal fatty acid–binding protein was positively associated with VIS (vasoactive-inotrope score) (p = 0.04). |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | vasoactive-inotrope score |
| p Value | 0.04 |
| Conclusion | Children undergoing cardiopulmonary bypass for repair or palliation of congenital heart disease are at risk for intestinal injury and often present with evidence for loss of intestinal epithelial integrity preoperatively. Greater severity of illness requiring increased cardiopulmonary support rather than the inflammatory response to cardiopulmonary bypass seems to mediate late postoperative intestinal epithelial barrier function |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 563 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF/SD/AVC/AS/SS/CoA, HAA/MV/TAPVR/PS/PA/PI/DORV/EA |
| Reference | |
|---|---|
| PMID | 25162512 |
| Year | 2015 |
| Title | Clinical characteristics associated with postoperative intestinal epithelial barrier dysfunction in children with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood, urine | |
| Region | Tucson, USA | |
| Method | ELISA, triple-quadrupole mass spectrometer, Cytokine concentrations were evaluated using an xMAP assay and Luminex 100 platform, HPLC | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | repair or palliation of congenital heart disease with cardiopulmonary bypass. | |
| Group | N/A(Treatment) | N/A(Control) |
| Number | 20 | N/A |
| Age | 17 (3.1–76.9) months | N/A |
| Gender (Male: Female) | 14:20 | N/A |
| Marker Level | N/A | N/A |
