| Factor Information | |
|---|---|
| Data ID | 1902 |
| Factor | correlation between Citrulline and larger arteriovenous oxygen saturation difference |
| Description | Citrulline was associated with larger (AVDO2) arteriovenous oxygen saturation difference (p = 0.04) and had a complex relationship with vasoactive-inotrope score. |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | prognosis and risk assessment |
| Objective | larger arteriovenous oxygen saturation difference |
| p Value | 0.04 |
| Conclusion | Children undergoing cardiopulmonary bypass for repair or palliation of congenital heart disease are at risk for intestinal injury and often present with evidence for loss of intestinal epithelial integrity preoperatively. Greater severity of illness requiring increased cardiopulmonary support rather than the inflammatory response to cardiopulmonary bypass seems to mediate late postoperative intestinal epithelial barrier function |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 563 |
| CHD Type | isolated CHD/non-isolated CHD |
| CHD Subtype | TOF/SD/AVC/AS/SS/CoA, HAA/MV/TAPVR/PS/PA/PI/DORV/EA |
| Reference | |
|---|---|
| PMID | 25162512 |
| Year | 2015 |
| Title | Clinical characteristics associated with postoperative intestinal epithelial barrier dysfunction in children with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood, urine | |
| Region | Tucson, USA | |
| Method | ELISA, triple-quadrupole mass spectrometer, Cytokine concentrations were evaluated using an xMAP assay and Luminex 100 platform, HPLC | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | repair or palliation of congenital heart disease with cardiopulmonary bypass. | |
| Group | N/A(Treatment) | N/A(Control) |
| Number | 20 | N/A |
| Age | 17 (3.1–76.9) months | N/A |
| Gender (Male: Female) | 14:20 | N/A |
| Marker Level | N/A | N/A |
