| Factor Information | |
|---|---|
| Data ID | 1926 |
| Factor | the history of aorto-pulmonary shunt |
| Description | Forty-four patients (44.4%) demonstrated high radial augmentation index (>1 SD of age- and gender matched control) and the determinants of the elevated radial augmentation index were the history of aorto-pulmonary shunt (odds ratio, 21.32; 95%CI, 5.47–83.14; p < 0.0001) and the direct aortic surgery (4.18; 1.38–12.72; p = 0.012). |
| Biomarker | YES |
| Classification | A3 (clinical factor - disease & symptom) |
| Association | |
|---|---|
| Application | risk assessment |
| Objective | to elucidate the risk factors of the enhanced pressure wave reflection in adult patients with congenital heart disease. |
| p Value | <0.0001 |
| OR | 21.32 |
| Conclusion | The history of aortic surgeries enhances aortic pressure wave reflection in adult patients with congenital heart disease. The enhanced aortic pressurewave reflection is one of the risk factors for cardiovascular diseases. |
| Risk Factor | risk factor |
| CHD Type | |
|---|---|
| ID | 566 |
| CHD Type | isolated CHD |
| CHD Subtype | TOF/SV/AC/IAA/VSD/ASD/TGA/EA/ccTGA/TA/other |
| Reference | |
|---|---|
| PMID | 25012495 |
| Year | 2014 |
| Title | Aortic surgery is one of the risk factors for enhancement of pressure wave reflection in adult patients with congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | Adults | |
| Source | N/A | |
| Region | Chiba, Japan | |
| Method | N/A | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | Aortic surgery:Direct aortic surgery, Aorto-pulmonary shun; Medication:ACEI/ARB, Diuretics, Beta blockers | |
| Group | >1 SD(Treatment) | <1 SD(Control) |
| Number | 20 (total: 44) | 3 (total:55) |
| Age | 31.5 ± 13.9 years | 39.7 ± 14.2 years |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | 20 (45.5%) | 3 (5.5%) |
