| Factor Information | |
|---|---|
| Data ID | 2018 |
| Factor | MTHFR expression |
| Description | N/A |
| Biomarker | NA |
| Classification | D2 (molecular factor - gene expression) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | children with PH |
| p Value | 0.02 |
| Conclusion | The OD value of MTHFR was statistically different between the PH and control groups. |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 577 |
| CHD Type | isolated CHD |
| CHD Subtype | ASD/VSD/PDA/ES/PAH |
| Reference | |
|---|---|
| PMID | 24571884 |
| Year | 2014 |
| Title | Potential biomarkers predicting risk of pulmonary hypertension in congenital heart disease: the role of homocysteine and hydrogen sulfide. |
| Sample | ||
|---|---|---|
| Population | children | |
| Source | blood | |
| Region | Guangzhou,China | |
| Method | univariate analysis | |
| Race | Asian | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | children with PH(Treatment) | children without PH(control)(Control) |
| Number | 77 | 81 |
| Age | 3.90±6.02 years | 4.05±3.77 years |
| Gender (Male: Female) | 38:39 | 45:38 |
| Marker Level | 0.129±0.041 | 0.1618±0.076 |
