| Factor Information | |
|---|---|
| Data ID | 2168 |
| Factor | association between preoperative MRSI measures of NAA/choline and preoperative brain injury score ( coefficients) |
| Description | An increasing preoperative brain injury score was associated with lower white matter FA (ratio was 3.0% lower for each point increase in injury score, p = 0.005) and lower NAA/choline (1.2% lower for each point increase in injury score, p = 0.01) |
| Biomarker | NA |
| Classification | Z (combined factor - combined factor) |
| Association | |
|---|---|
| Application | prognosis |
| Objective | To determine the relationship between radiologically identifiable brain injuries and delayed brain development as reflected by brain metabolic and microstructural integrity. |
| p Value | 0.01 |
| Conclusion | An increasing preoperative brain injury score was associated with lower white matter FA (ratio was 3.0% lower for each point increase in injury score, p = 0.005) and lower NAA/choline (1.2% lower for each point increase in injury score, p = 0.01) |
| Risk Factor | unknown |
| CHD Type | |
|---|---|
| ID | 587 |
| CHD Type | isolated CHD |
| CHD Subtype | TGA/SV/AC/PA/TOF/TA/TAPVC |
| Reference | |
|---|---|
| PMID | 23771484 |
| Year | 2013 |
| Title | Brain injury and development in newborns with critical congenital heart disease. |
| Sample | ||
|---|---|---|
| Population | neonates | |
| Source | a dual-center prospective cohort study | |
| Region | Vancouver, Canada | |
| Method | Cross-sectional analyses | |
| Race | North America | |
| Disease History | N/A | |
| Treatment History | N/A | |
| Group | Preoperative brain injury score(Treatment) | N/A(Control) |
| Number | 120 | N/A |
| Age | 5 days (range 1–43) | N/A |
| Gender (Male: Female) | N/A | N/A |
| Marker Level | -0.012(coefficients) | N/A |
